Results 91 to 100 of about 8,886,497 (252)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Folder 6: Model engine data sheets and operating instructions, J - N, ca. 1960, 1972, 1988
, 1960 Instructions, illustrations, and parts price list for a Dynamic Models, INC. Johnson Engines.
Dynamic Models, Inc.
core
Fitting physiological models to data
, 1984 Methods of fitting models to experimental data obtained from biological systems are reviewed. The Michaelis-Menten model is used as the working example of a familiar and well-studied biological model.
D. Garfinkel, K. A. Fegley
core +1 more source
Optimizing Emergency Stroke Transport Strategies Using Physiological Models. [PDF]
Stroke, 2021 Paydarfar DA +3 more
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
La importancia de la fisiología comparada en las titulaciones en ciencias de la salud y de la vida
Educación MédicaResumen: La fisiología comparada ofrece un enfoque integral para comprender los mecanismos fisiológicos de los seres vivos, situándolos en un contexto evolutivo y ecológico.
Daniel Cabello-Rivera +1 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
, 2005 F. OLIVA MD, U. Tarantino MD, N. Maffulli MD, MS, PhD, FRCS(Orth) . "Immunohistochemical localization of Calcitonin Gene-Related Peptide and Substance P in the rat knee cartilage at birth" Physiological Research 2005;55(5):549 ...
OLIVA F +4 more
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Frontiers in Amphibian and Reptile ScienceIntroductionSpecies distribution models (SDMs) are essential tools for assessing the conservation status of species, because they provide crucial insights into their ecological requirements and potential geographic distribution.
Hibraim Adán Pérez-Mendoza +11 more
doaj +1 more source