Results 31 to 40 of about 4,018 (220)
Archaeological bone lipids as palaeodietary markers [PDF]
Rationale Stable isotope analysis of archaeological and fossil bone samples can provide important insights into past environments, ecologies and diets.
Alexander, Michelle Marie +7 more
core +1 more source
ω-Hydroxylation of phytanic acid in rat liver microsomes
The 3-methyl-branched fatty acid phytanic acid is degraded by the peroxisomal α-oxidation route because the 3-methyl group blocks β-oxidation. In adult Refsum disease (ARD), peroxisomal α-oxidation is defective, which is caused by mutations in the gene ...
J.C. Komen, M. Duran, R.J.A. Wanders
doaj +1 more source
Cooking fish and drinking milk? Patterns in pottery use in the southeastern Baltic, 3300–2400 cal BC [PDF]
yesA study of pottery vessel contents and use was undertaken in order to obtain information on food processed in Subneolithic and Neolithic vessels from Nida and Šventoji (3300–2400 cal BC).
Ackman +59 more
core +1 more source
ACOX2 deficiency: A disorder of bile acid synthesis with transaminase elevation, liver fibrosis, ataxia, and cognitive impairment [PDF]
Acyl CoA Oxidase 2 (ACOX2) encodes branched-chain acyl-CoA oxidase, a peroxisomal enzyme believed to be involved in the metabolism of branched-chain fatty acids and bile acid intermediates. Deficiency of this enzyme has not been described previously.
Akyol, G +10 more
core +1 more source
Pristanic acid and phytanic acid are branched-chain fatty acids, which play an important role in diseases with peroxisomal impairment, like Refsum disease (MIM 266500), Zellwegers syndrome and α-methylacyl-CoA racemase deficiency (MIM 604489).
Sabine Rönicke +3 more
doaj +1 more source
The accumulation of the two branched-chain fatty acids phytanic acid and pristanic acid is known to play an important role in several diseases with peroxisomal impairment, like Refsum disease, Zellweger syndrome and α-methylacyl-CoA racemase deficiency ...
Nicol Kruska, Georg Reiser
doaj +1 more source
Metabolism of phytol-U-14C and phytanic acid-U-14C in the rat
The metabolism of uniformly-labeled 14C-phytol, 14C-phytenic acid, and 14C-phytanic acid was studied in the rat. Conversion of both phytol and phytenic acid to phytanic acid was demonstrated.
Charles E. Mize +4 more
doaj +1 more source
Refsum disease: a defect in the alpha-oxidation of phytanic acid in peroxisomes
The oxidation of phytanic acid to pristanic acid was previously demonstrated to be deficient in monolayer cultures of skin fibroblasts (Herndon et al. 1969. J. Clin. Invest. 48: 1017-1032).
I Singh, K Pahan, AK Singh, E Barbosa
doaj +1 more source
Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults. [PDF]
Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are involved in energy metabolism and biosynthesis of nucleic acids whereas others ...
Adams +154 more
core +2 more sources
Formate Excretion in Urine of Rats Fed Dimethylaminoazobenzene-rich Diets: The Possibility of Formate Formation from D-Lactate [PDF]
This experiment was carried out to evaluate the possibility of degradation of d-lactate into formate and acetaldehyde. In order to induce hyperproduction of d-lactate in rats.
Kawase, Michi +2 more
core +1 more source

