Results 171 to 180 of about 1,063,869 (264)

Molecular Evolution and Related Defense Response of Pi-ta Gene in Wild Rice (Oryza rufipogon)

, 2013
Pi-ta為水稻抗病（R）蛋白質，可專一性的辨識稻熱病病原菌的致病因子AVRpita，啟動抗病反應。此研究分析36個亞洲野生稻O. rufipogon的Pi-ta基因序列，經排列比較的結果，可以分成兩類基因群：H1及H2；藉由與外群非洲野生稻O. barthii比較，可推論H1衍生自H2。已知Pi-ta的第918胺基酸為決定對AVRpita的辨識專一性，由最大似然樹的結果，H1與水稻的Pi-ta分在同一個支序內，在第918胺基酸同樣為具有抗病性的丙胺酸，而H2則全都為不具抗病性的絲胺酸 ...
黃俊霖, Huang, Chun-Lin
core  

Iron-Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti-Tumor Immunity in Colorectal Cancer. [PDF]

Adv Sci (Weinh)
Zhu Y, Yu X, Wang T, Liu W, Lu C, Zhong J, He Y, Li W, Zhang K, Yin P, Yuan Z.   +10 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Suppressed excitonic effects enable high mobility and high-yield photoconductivity in a pyridine-coordinated two-dimensional polymer crystal. [PDF]

Nat Commun
Fu S, Yang Y, Gao G, Zhao S, Položij M, Zhu T, Gao L, Heine T, Wang Z, Bonn M, Feng X.   +10 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Skeletal Muscle-Derived Extracellular Vesicles During Eccentric and Concentric Exercise Promote Muscle Regeneration After Injury. [PDF]

J Cachexia Sarcopenia Muscle
Zhou Y, Shao X, Zhang P, Lin J, Chen X, An X, Jiang Z, Wang H, Fang D, Xian Y, Liu B, Shen T, Chen Y, Li K, Liu H, Li Y, Jiang Q, Guo B.   +17 more
europepmc   +1 more source

Establishment and Application of Multiplex PCR System for Two Blast Resistance Genes Pi-ta and Pi-b in Rice

Acta Agronomica Sinica, 2014
Shu YAO, Yan-Qing LIU, Ya-Dong ZHANG, Zhen ZHU, Tao CHEN, Qing-Yong ZHAO, Li-Hui ZHOU, Chun-Fang ZHAO, Xin YU, Cai-Lin WANG   +9 more
openaire   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Basal Energetics and Phosphocreatine Recovery Kinetics in Ambulatory Boys With Duchenne Muscular Dystrophy. [PDF]

NMR Biomed
Awale PP, Lopez C, Taivassalo T, Vandenborne K, Walter GA, Forbes SC.   +5 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source