Results 61 to 70 of about 261,386 (249)

Corrigendum to “Symplectic and orthogonal $K$-groups of the integers”

Comptes Rendus. Mathématique
The action of the duality functor on the odd torsion of $K_n(\mathbb{Z})$ was stated incorrectly in [3], in half of the cases, and lead to incorrect formulas for the odd primary torsion of $\pi _nB\mathrm{Sp}(\mathbb{Z})^+$ and $\pi _nBO_{\infty ,\infty }
Schlichting, Marco
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Characterization of alpha-1 antitrypsin in a Pi∗ZZ patient with emphysema: a case report

Respiratory Medicine Case Reports
Background: Lung disease severity and progression vary widely among individuals with severe alpha-1 antitrypsin deficiency (AATD; Pi∗ZZ, Glu342Lys). In addition to low levels of polymerized Z mutant AAT (Z-AAT), this variability may result from other ...
Arturo Olivares Rivera, Julia Held, Julia Beimdiek, Falk F.R. Buettner, Claus P. Heußel, Sabina Janciauskiene, Franziska Trudzinski   +6 more
doaj   +1 more source

Pion and Kaon Polarizabilities at CERN COMPASS [PDF]

, 2003
The electric alpha and magnetic beta pion Compton polarizabilities characterize the pion's deformation in the electromagnetic field of the gamma during gamma-pi Compton scattering.
Moinester, Murray
core   +1 more source

On surrogate loss functions and $f$-divergences

, 2008
The goal of binary classification is to estimate a discriminant function $\gamma$ from observations of covariate vectors and corresponding binary labels.
Jordan, Michael I., Nguyen, XuanLong, Wainwright, Martin J.   +2 more
core   +4 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Prevalence of Alpha-1 Antitrypsin Deficiency Alleles in a Lithuanian Cohort of Wheezing Small Children

Advances in Respiratory Medicine
Severe inherited alpha-1 antitrypsin deficiency (AATD) is an autosomal genetic condition linked to chronic obstructive pulmonary disease (COPD). The significance of heterozygous, milder deficiency variants (PiSZ, PiMZ, PiMS) is less clear.
Edita Poluzioroviene, Joanna Chorostowska-Wynimko, Sigita Petraitiene, Arunas Strumila, Adriana Rozy, Aneta Zdral, Arunas Valiulis   +6 more
doaj   +1 more source

Зростання канонічних добутків Вейєрштрасса нульового роду з випадковими нулями

Karpatsʹkì Matematičnì Publìkacìï, 2013
Нехай $\zeta=(\zeta_n)$ - комплексна послідовність нульового роду з показником збіжності $\tau$, $N(r)$ - її усереднена лічильна функція, $\pi(z)=\prod\bigl(1-\frac{z}{\zeta_n}\bigr)$ - канонічний добуток Вейєрштрасса, а $M(r)$ - максимум модуля цього ...
Yu.B. Zakharko, P.V. Filevych
doaj   +1 more source

Optimizing expected word error rate via sampling for speech recognition

, 2017
State-level minimum Bayes risk (sMBR) training has become the de facto standard for sequence-level training of speech recognition acoustic models. It has an elegant formulation using the expectation semiring, and gives large improvements in word error ...
Shannon, Matt
core   +1 more source