Results 181 to 190 of about 64,413 (204)

Quantitative FRET Microscopy Reveals a Crucial Role of Cytoskeleton in Promoting PI(4,5)P₂ Confinement. [PDF]

Int J Mol Sci, 2021
Sarmento MJ, Borges-Araújo L, Pinto SN, Bernardes N, Ricardo JC, Coutinho A, Prieto M, Fernandes F.   +7 more
europepmc   +1 more source

β-arrestin-dependent PI(4,5)P₂ synthesis boosts GPCR endocytosis. [PDF]

Proc Natl Acad Sci U S A, 2021
Jung SR, Jiang Y, Seo JB, Chiu DT, Hille B, Koh DS.   +5 more
europepmc   +1 more source

Molecular basis of product recognition during PIP5K-mediated production of PI(4,5)P₂ with positive feedback. [PDF]

J Biol Chem
Duewell BR, Faris KA, Hansen SD.
europepmc   +1 more source

BIG1 controls macrophage pro-inflammatory responses through ARF3-mediated PI(4,5)P2 synthesis. [PDF]

Cell Death Dis, 2020
Liu L, Zhang S, Wang Y, Bao W, Zhou Y, Dang W, Wang X, Li H, Cao X, You Y, Fang H, Shen X.   +11 more
europepmc   +1 more source

MARCKS and PI(4,5)P₂ reciprocally regulate actin-based dendritic spine morphology. [PDF]

Mol Biol Cell
Calabrese B, Halpain S.
europepmc   +1 more source

A distinctive PI(4,5)P₂compartment forms during entosis and related engulfment processes

Durgan J, Sloan K, Domart M, Collinson LM, Florey O.   +4 more
europepmc   +1 more source

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Disarming PI(4,5)P2 in the plasma membrane

Nature Plants, 2021
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is involved in lipid-mediated intracellular signalling and the regulation of events such as cytoskeletal reorganization and membrane trafficking. An inducible PI(4,5)P2 depletion system is now available for examining its function in plant cells.
Bo Liu, Xiaojiang Guo
openaire   +2 more sources

PI(4,5)P2 and Cholesterol: Synthesis, Regulation, and Functions

2023
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is the most abundant membrane phosphoinositide and cholesterol is an essential component of the plasma membrane (PM). Both lipids play key roles in a variety of cellular functions including as signaling molecules and major regulators of protein function.
Avia, Rosenhouse-Dantsker, Dimitris, Gazgalis, Diomedes E, Logothetis   +2 more
openaire   +2 more sources

The PI(3,5)P2 and PI(4,5)P2 Interactomes

Journal of Proteome Research, 2008
A comprehensive analysis of the phosphoinositide interactome has been performed using analogues of PI(3,5)P2 and PI(4,5)P2 phosphatidyl phospholipids which were immobilized onto Affi-10 beads or incorporated into liposomes for use as affinity absorbents with cytosolic extracts from colonic carcinoma cell lines.
Bruno, Catimel, Christine, Schieber, Melanie, Condron, Heather, Patsiouras, Lisa, Connolly, Jenny, Catimel, Edouard C, Nice, Antony W, Burgess, Andrew B, Holmes   +8 more
openaire   +2 more sources