Results 181 to 190 of about 62,994 (190)

Polyamines, PI(4,5)P₂, and actin polymerization

Journal of Cellular Physiology, 2006
AbstractSpermine (SPM) and spermidine (SPD) activate isolated phosphatidylinositol‐4‐phosphate 5‐kinases (PI(4)P5K), enzymes that convert phosphatidylinositol‐4‐phosphate to phosphatidylinositol 4,5‐bisphosphate (PI(4,5)P2). PI(4,5)P2 formation is known to be involved in cellular actin reorganization and motility, functions that are also influenced by ...
Ronald F, Coburn, Edward F, Labelle, Carl B, Baron   +2 more
openaire   +2 more sources

Phosphoinositide 5-phosphatase activities control cell motility in glioblastoma: Two phosphoinositides PI(4,5)P2 and PI(3,4)P2 are involved

Advances in Biological Regulation, 2018
Inositol polyphosphate 5-phosphatases or phosphoinositide 5-phosphatases (PI 5-phosphatases) are enzymes that can act on soluble inositol phosphates and/or phosphoinositides (PIs). Several PI 5-phosphatases have been linked to human genetic diseases, in particular the Lowe protein or OCRL which is mutated in the Lowe syndrome.
Ramos, Ana Raquel, Elong Edimo, William's, Erneux, Christophe   +2 more
openaire   +3 more sources

PI(4,5)P2 regulation of surface membrane traffic

Current Opinion in Cell Biology, 2001
Phosphatidylinositol 4,5-biphosphate (PI[4,5]P(2)) has emerged as an important signaling molecule in the membrane for regulating vesicle exo- and endocytosis and the accompanying actin cytoskeletal rearrangements. Localization studies with GFP-tagged binding domains and antibodies provide new views of the non-uniform, dynamic distribution of PI(4,5)P(2)
openaire   +2 more sources

Cdc42 and PI(4,5)P2‐Induced Actin Assembly in Xenopus Egg Extracts

2006
Xenopus egg cytoplasmic extracts have been used to study a variety of complex cellular processes. Given their amenability to biochemical manipulation and physiological balance of regulatory proteins, these extracts are an ideal system to dissect signal transduction pathways leading to actin assembly.
Andres M, Lebensohn, Le, Ma, Hsin-Yi Henry, Ho, Marc W, Kirschner   +3 more
openaire   +2 more sources

PI4P and PI(4,5)P2 immunofluorescence staining optimization in human platelets

2021
Background: Phosphatidylinositol-4-phosphate (PI4P) is a phosphoinositide found mostly at the Golgi apparatus and partially at the plasma membrane (PM). At the PM, PI4P can contribute to the polyanionic lipid pool or can serve for the formation of phosphatidylinositol-4, 5-bisphosphate [PI(4, 5)P2].
Bura, Ana, Đurić, Iris, Čabrijan, Sara, Jurak Begonja, Antonija   +3 more
openaire   +1 more source

Regulation of actin-binding proteins by PI(4,5)P2

Biophysical Journal, 2023
openaire   +1 more source

PI(4,5)P2 Required for Recovery

Science Signaling, 2002
openaire   +1 more source

Faculty Opinions recommendation of The PI(3,5)P2 and PI(4,5)P2 interactomes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2009
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Cholesterol and PI(4,5)P2 in Vital Biological Functions

2023
openaire   +1 more source

Ferroportin inhibition by PI(4,5)P2 and cholesterol

Biophysical Journal
Ce Liang, Yaping Pan, Arthur Laganowsky, Ming Zhou   +3 more
openaire   +1 more source