Results 91 to 100 of about 36,422 (221)

ATP modulates holdase activity of fungal and human 110‐kilodalton heat shock proteins to promote protein folding

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Heat shock proteins of the 70‐kDa family (Hsp70s) are highly abundant and conserved molecular chaperones that help preserve proteostasis primarily by facilitating proper protein folding. Heat shock protein of the 110‐kDa family (Hsp110s), a specialized branch of the Hsp70/Hsp110 superfamily, function both as nucleotide exchange factor (NEF ...
Justin M. Kidd, Cancan Sun, Alissa Garay, Mitchell Keplinger, Colin Richter, Aaron E. May, Qinglian Liu   +6 more
wiley   +1 more source

A roadmap to establish a comprehensive platform for sustainable manufacturing of natural products in yeast

Nature Communications, 2023
Yeasts, Saccharomyces cerevisiae and Pichia pastoris, are promising chassis for the production of nature products (NPs). Here, the author discusses establishing a comprehensive platform for sustainable production of NPs via system-associated optimization
Gita Naseri
doaj   +1 more source

Pichia pastoris ‘just in time’ alternative respiration [PDF]

Microbiology, 2007
Alternative oxidases (Aox or Aod) are present in the mitochondria of plants, fungi and many types of yeast. These enzymes transfer electrons from the ubiquinol pool directly to oxygen without contributing to the proton transfer across the mitochondrial membrane.
Alexander, Kern, Franz S, Hartner, Maria, Freigassner, Julia, Spielhofer, Cornelia, Rumpf, Laura, Leitner, Kai-Uwe, Fröhlich, Anton, Glieder   +7 more
openaire   +2 more sources

Utilization of Fermentation Process for the Production of Novel Plant‐Based Meat Analogs: A Review of Microorganisms, Processing, and Regulations

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The production of plant‐based meat analogues from various protein sources is an emerging application worldwide, driven by growing population and health concerns. Many microorganisms during fermentation play a crucial role in fermented plant‐based meat alternatives, together with structuring and analytical approaches in terms of nutritional ...
Fatma Beyza Özpınar, Sevda Dere, Serdar Altunay, Osman Sagdic, Enes Dertli   +4 more
wiley   +1 more source

Systems-level organization of yeast methylotrophic lifestyle [PDF]

, 2015
BACKGROUND: Some yeasts have evolved a methylotrophic lifestyle enabling them to utilize the single carbon compound methanol as a carbon and energy source. Among them, Pichia pastoris (syn.
Alexandra B. Graf, Ali Al Chalabi, Brigitte Gasser, Christina Troyer, Clemens Gruber, Denise Sonntag, Diethard Mattanovich, Friedrich Altmann, Gerda Modarres, Guido Krebiehl, Gunda Koellensperger, Günther Daum, Günther Zellnig, Hannes Rußmayer, Hedda Drexler, Karlheinz Grillitsch, Kristaps Klavins, Markus Buchetics, Matthias Steiger, Michael Sauer, Minoska Valli, Raffaele Guerrasio, Stefan Neubauer, Stephan Hann   +23 more
core   +4 more sources

Tenebrio molitor‐Derived Enzyme Systems Enable Solvent‐Reduced Recovery of Intracellular Polyhydroxyalkanoates

Microbial Biotechnology, Volume 19, Issue 5, May 2026.
Multi‐enzyme systems from Tenebrio molitor enable solvent‐free recovery of microbial PHAs directly from wet biomass under mild aqueous conditions, achieving high polymer yields and integrity while reducing carbon footprint up to seven‐fold compared with conventional extraction methods.
Sanja Skaro Bogojevic, Brana Pantelic, Marijana Ponjavic, Tatjana Ilic‐Tomic, Dusan Milivojevic, Maciej Guzik, Marcin Rychwalski, Romanos Siaperas, Evangelos Topakas, Mónica Carvalheira, Filomena Freitas, Patrícia Concórdio‐Reis, Jasmina Nikodinovic‐Runic   +12 more
wiley   +1 more source

Molecular Cloning and Production of Recombinant Phytase from Bacillus subtilis ASUIA243 in Pichia pastoris

International Islamic University Malaysia Engineering Journal, 2011
Phytase gene obtained from Bacillus subtilis ASUIA243 was cloned into a medium vector and transformed into E. coli. Restriction enzyme digestion was conducted to get blunt-ended phytase gene and ligated into the Pichia expression vector, pPICZαA.
Nor Soleha Mohd Dali, Tamrin Nuge, Mohd Hafidz Mahamad Maifiah, Faridah Yusof, Anis Shobirin Meor Hussin, Abd-Elaziem Farouk, and Hamzah Mohd. Salleh   +6 more
doaj   +1 more source

Perdeuteration of cholesterol for neutron scattering applications using recombinant Pichia pastoris [PDF]

, 2018
Deuteration of biomolecules has a great impact on both quality and scope of neutron scattering experiments. Cholesterol is a major component of mammalian cells, where it plays a critical role in membrane permeability, rigidity and dynamics, and ...
Adrian R. Rennie, Appolaire, Bergner, Blakeley, Braun, Browning, Campbell, Casadei, Cuypers, Cuypers, Cuypers, de Ghellinck, de Ghellinck, Diraison, Dunne, Edlich-Muth, Foglia, Fragneto, Gerelli, Gernot A. Strohmeier, Grage, Haertlein, Hagn, Harald Pichler, Haupt, Hemming, Hirz, Howard, Ibrahim, Katherine C. Thompson, Katz, Kessner, Kwon, Lee, Leitch, Lind, Maric, Maric, Marsh, Martine Moulin, Matthäus, Melanie Hirz, Micciulla, Michael Haertlein, Nelson, Rheinstädter, Richard A. Campbell, Schirò, Selma Maric, Sheridan, Small, Stockton, Thompson, Thompson, V. Trevor Forsyth, Vijayakrishnan   +55 more
core   +2 more sources

Engineering of 10‐Deacetylbaccatin III‐10‐β‐O‐Acetyltransferase From Taxus Species for Efficient Acetylating Non‐Natural Substrates Into Taxol in Nicotiana benthamiana

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3308-3323, May 2026.
ABSTRACT 7‐β‐xylosyl‐10‐deacetyltaxol (XDT) is much more abundant than the anticancer drug Taxol in Taxus species and is usually regarded as the by‐product of Taxol. It could be enzymatically transformed into 10‐deacetyltaxol (DT), and the latter could be further converted into Taxol.
Tian‐Jiao Chen, Jing‐Jing Chen, Xiao‐Yan Sun, Ting Gong, Jin‐Ling Yang, Ping Zhu   +5 more
wiley   +1 more source

Expression, purification and application of recombinant Pediocin from Pichia pastoris X33::ped in shrimp preservation trial

Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ
Pediocin (Ped) is a 4.6kDa bacteriocin effective against Listeria monocytogenes and several Gram-positive bacteria. To produce purified Ped with high yield and apply it to food preservation, this study expresses and purifies recombinant Ped (rPed) from ...
Nguyễn Phạm Anh Thư, Đặng Thị Phương Thảo, Nguyễn Hiếu Nghĩa   +2 more
doaj   +1 more source