Results 71 to 80 of about 21,652 (231)
ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn +12 more
wiley +1 more source
Production of enterocin P by a bioengineered Pichia pastoris to control of pathogen bacteria [PDF]
Entrocin p has been characterized in class IIa bacteriocins and showed a broad spectrum of antimicrobial activity. In this study, the nucleotide sequence of enterocin P transformed and expressed in Pichia pastoris genomically, and antimicrobial activity ...
Abbas Tanhaeian +2 more
doaj +1 more source
The power of many: when genetics met yeasts and high‐throughput
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
Metabolism of Hydrogen Peroxide byPichia pastoris [PDF]
Hydrogen peroxide in methylotrophic yeasts can be metabolized in at least two distinct ways. Addition of exogenous hydrogen peroxide removes the dependance of catalase on endogenously-produced hydrogen peroxide resulting enhanced rates of alcohol oxidation.
DUFF, Sheldon J. B., MURRAY, William D.
openaire +2 more sources
High level production, characterization and structural analysis of neuronal calcium-activated potassium channels [PDF]
Kaliumkanäle vermitteln als reguliertes Porenprotein den selektiven Transport von Kaliumionen durch die Zellmembran. Sie sind für physiologische Prozesse wie Neurosekretion und Tonus der glatten Muskulatur von Bedeutung.
Licata, Luana, Licata, L.
core
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source
The effect of hypoxia on the lipidome of recombinant Pichia pastoris [PDF]
Cultivation of recombinant Pichia pastoris (Komagataella sp.) under hypoxic conditions has a strong positive effect on specific productivity when the glycolytic GAP promoter is used for recombinant protein expression, mainly due to upregulation of glycolytic conditions. In addition, transcriptomic analyses of hypoxic P.
Núria Adelantado +8 more
openaire +5 more sources
Expression and characterization of recombinant beta-xylosidase from Trichoderma reesei ATCC 58350 in Pichia pastoris [PDF]
B-xylosidase is one of the essential enzymes for complete breakdown of xylan since it degrades short xylo-oligosaccharides and hydrolyzed xylobiose by endoxylanases to xylose.
Muhammad Zaidi, Nor Fadzilah
core
Production of in vivo biotinylated scFv specific to almond (Prunus dulcis) proteins by recombinant Pichia pastoris [PDF]
The methylotropic yeast Pichia pastoris has demonstrated its suitability for large-scale production of recombinant proteins. As an eukaryotic organism P.
García Lacarra, Teresa +6 more
core +1 more source
Complement Factor H‐Based Therapeutics: A Comprehensive Overview
Complement factor H is a central regulator of the complement system and thus a target for therapeutic intervention. In this review, we provide an overview of past and current factor H‐based therapeutic concepts and modalities to treat complement‐mediated diseases.
Sebastiaan M. W. R. Hamers +2 more
wiley +1 more source

