Results 51 to 60 of about 12,411 (173)

The genomic and epidemiological investigations of enteric viruses of domestic caprine (Capra hircus) revealed the presence of multiple novel viruses related to known strains of humans and ruminant livestock species

open access: yesMicrobiology Spectrum, 2023
In this study, the enteric virome of diarrheic caprine was investigated using next-generation sequencing, reverse transcription PCR methods, and bioinformatics analyses.
Ákos Boros   +7 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

THE ENCEPHALOMYOCARDITIS VIRUS (EMCV) AND ITS ZOONOTIC POTENTIAL (A Literature Review) PART I. MODERN VIEWS ON THE EMCV STRUCTURE AND ITS VIRAL CYCLE

open access: yesКубанский научный медицинский вестник, 2019
There have been a growing number of the outbreaks of human diseases with typical zoonotic infections, which have previously occurred exclusively in veterinary practice.
Akop A. Kalajdzhjan   +3 more
doaj   +1 more source

Influence of genome-scale RNA structure disruption on the replication of murine norovirus--similar replication kinetics in cell culture but attenuation of viral fitness in vivo [PDF]

open access: yes, 2013
Mechanisms by which certain RNA viruses, such as hepatitis C virus, establish persistent infections and cause chronic disease are of fundamental importance in viral pathogenesis.
Evans, David J   +8 more
core   +1 more source

Advances and perspectives in animal models of human hepatitis A virus

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Following HAV infection, humans, non‐human primates, and Ifnar1−/− mice develop characteristic manifestations of hepatitis A, including fecal viral shedding, elevated serum ALT levels, and inflammatory cell infiltration in the liver. In contrast, HAV‐infected human liver chimeric mice exhibit fecal viral shedding but do not develop clinical features of
Jian Li   +3 more
wiley   +1 more source

Viral Infections of Humans: Epidemiology and Control [PDF]

open access: yes
Rhinoviruses belong to a large group of RNAviruses that include 169 virus types classified in three species, A, B, and C, in the Picornaviridae family and the Enterovirus genus. Rhinoviruses replicate in the nasopharynx and the resulting infections maybe
Peltola Ville, Susi Petri, Jartti Tuomas
core   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

open access: yesAnimal Research and One Health, EarlyView.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng   +7 more
wiley   +1 more source

Iflaviruses in arthropods: when small is mighty

open access: yesInsect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia   +3 more
wiley   +1 more source

Nucleosides for the treatment of respiratory RNA virus infections

open access: yes, 2018
Influenza virus, respiratory syncytial virus, human metapneumovirus, parainfluenza virus, coronaviruses, and rhinoviruses are among the most common viruses causing mild seasonal colds.
Sarah K Stevens   +2 more
core   +1 more source

Development and Large-Scale Testing of a Novel One-Step Triplex RT-qPCR Assay for Simultaneous Detection of “Neurotropic” Porcine Sapeloviruses, Teschoviruses (Picornaviridae) and Type 3 Porcine Astroviruses (Astroviridae) in Various Samples including Nasal Swabs

open access: yes, 2022
Porcine sapeloviruses, teschoviruses of family Picornaviridae and type 3 porcine astroviruses of family Astroviridae are (re-)emerging enteric pathogens that could be associated with severe, disseminated infections in swine, affecting multiple organs ...
Gábor Gáspár   +8 more
core   +1 more source

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