Results 91 to 100 of about 21,155 (219)

Cardiomyopathy in Offspring of Pregestational Diabetic Mouse Pregnancy [PDF]

, 2014
Purpose. To investigate cardiomyopathy in offspring in a mouse model of pregestational type 1 diabetic pregnancy. Methods. Pregestational diabetes was induced with STZ administration in female C57BL6/J mice that were subsequently mated with healthy ...
Baugh, John, Corrigan, Niamh, Dowling, Daniel, Downey, Paul, Horgan, Stephen, McAuliffe, Fionnuala M, Watson, Chris J   +6 more
core   +3 more sources

Liver Stiffness Characterization of OGTLKO Mouse Model of Progressive Liver Fibrosis

Journal of Ultrasound in Medicine, EarlyView.
Objectives O‐GlcNAcylation plays a key regulatory role in hepatic physiology, and its disruption leads to fibrosis in liver‐specific OGT knockout mice (OGTLKO), making this model valuable for studying advanced metabolic dysfunction‐associated steatohepatitis (MASH).
Gilles Renault, Lenin Chinchilla, Lourdes Massengo, Pierre Monbernard, Fadila Benhamed, Marion Regnier, Raphael Denis, Catherine Postic, Anthony Novell, Jean‐Luc Gennisson   +9 more
wiley   +1 more source

Colagenoma eruptivo em paciente HIV+ Eruptive collagenoma in an HIV-positive patient

Anais Brasileiros de Dermatologia, 2008
Colagenomas são hamartomas do tecido conjuntivo gerados por aumento anormal do colágeno dérmico. O colagenoma eruptivo caracteriza-se por pequenos nódulos duros, assintomáticos, sem relato de trauma ou processo inflamatório prévios.
Daniel Dal'Asta Coimbra, Joana Cabral Lustosa, Denise de Freitas Sarmento, Ricardo Barbosa Lima, Osvania M. N. Pessoa   +4 more
doaj   +1 more source

A structural approach including the behavior of collagen cross-links to model patient-specific human carotid arteries [PDF]

, 2014
The final publication is available at Springer via http://dx.doi.org/10.1007/s10439-014-0995-7The objective of this work is to develop a remodeling model for biological matter coupling two different processes in a 3D framework: reorientation of the ...
Martínez, Miguel Angel, Peña, Estefanía, Sáez Viñas, Pablo   +2 more
core   +2 more sources

Amentoflavone, a Preferentially TGF‐β Receptor 1 Inhibitor, Alleviates Cardiac Remodeling and Dysfunction Through Modulating the TGF‐β/Smad and MAPK Signaling Pathways

Phytotherapy Research, EarlyView.
Amentoflavone, a preferentially TGF‐ββ receptor 1 inhibitor, attenuates transverse aortic constriction (TAC)‐triggered cardiac hypertrophy, fibrosis, and dysfunction by suppressing downstream Smad and MAPK signaling cascades in cardiomyocytes and cardiac fibroblasts.
Jiangjiao Wu, Chengcheng Zhao, Xiaoping Li, Xinyi Guo, Wenjie Tan, Lu Zhou, Ye Zhang, Jianli Zhang, Shuo Zheng, Chunyu Zeng, Gengze Wu   +10 more
wiley   +1 more source

PICROSIRIUS RED AND MASSON'S TRICHROME STAINING TECHNIQUES AS TOOLS FOR DETECTION OF COLLAGEN FIBERS IN THE SKIN OF DOGS WITH ENDOCRINE DERMATOPATHOLOGIES

Ciência Animal Brasileira, 2019
Canine endocrinopathies, such as hypothyroidism and hyperadrenocortism,induce typical dermatological alterations. Collagen fibers are significant for the maintenance of structural integrity,as well as in the determination of tissue function.
Glícia Meneses Costa, Steffi Lima Araujo, Francisco Antônio Félix Xavier Júnior, Glayciane Bezerra de Morais, João Alison de Moraes Silveira, Daniel de Araújo Viana, Janaina Serra Azul Monteiro Evangelista   +6 more
doaj  

In Vivo Photoacoustic Ultrasound (PAUS) Assay for Monitoring Tendon Collagen Compositional Changes during Injury and Healing

Diagnostics
Tendon injury and healing involve significant changes to tissue biology and composition. Current techniques often require animal sacrifice or tissue destruction, limiting assessment of dynamic changes in tendons, including treatment response, disease ...
Joseph B. Newton, Courtney A. Nuss, Stephanie N. Weiss, Rebecca L. Betts, Chandra M. Sehgal, Louis J. Soslowsky   +5 more
doaj   +1 more source

Structure, ontogeny and evolution of the patellar tendon in emus (Dromaius novaehollandiae) and other palaeognath birds [PDF]

, 2014
The patella (kneecap) exhibits multiple evolutionary origins in birds, mammals, and lizards, and is thought to increase the mechanical advantage of the knee extensor muscles.
Alexander, Baker, Baraibar, Beale, Beale, Benjamin, Biggs, Bland, Bourdon, Bourdon, Brinkmann, Buck, Chadwick, Chiappe, Clarke, Clarke, Cooper, Cracraft, de Vriese, Deeming, Drenowatz, Dye, Fowler, Gadow, Gadow, Gagliano, Gangl, Goetz, Goonewardene, Hackett, Haines, Haines, Harshman, Hashimoto, Haughton, Hogg, Hou, Houde, Hutchinson, Johnston, Järvinen, Józsa, Kaiser, Khan, Lansdown, Lee, Livezey, Livezey, Macalister, Maddison, Maisano, Maxwell, McGowan, Mitchell, Naldo, Owen, Owen, O’Brien, Parker, Parsons, Patak, Pearson, Phillips, Picasso, Pourlis, Reese, Sales, Sarin, Schweitzer, Shanthi, Sharma, Smith, Spencer, Stannius, Stewart, Sánchez-Villagra, Thompson, Turvey, Turvey, Vickaryous, Vigorita, Vogel, von Kossa, Wang, Zhou   +84 more
core   +3 more sources

Hederagenin Attenuates Cardiac Remodeling by Targeting Phosphodiesterase 9A

Phytotherapy Research, EarlyView.
ABSTRACT Background and Aim New therapeutic strategies for heart failure are urgently needed. The protective effects of cyclic guanosine monophosphate (cGMP)—protein kinase G (PKG) pathway on heart have been widely reported. Despite phosphodiesterase 9A (PDE9A) inhibitors combating cardiac remodeling, clinically available drugs are lacking. Hederagenin
Liqian Chen, Xinghong Zhou, Yanting You, Jieyu Chen, Baizhao Peng, Yijian Deng, Shuai Ji, Ying Yang, Xiaohu Chen, Huaxi Liu, Shuxuan Yang, Hiu Yee Kwan, Wen Jin, Lei Zhang, Yuegang Wang, Xiaoshan Zhao, Yanyan Liu   +16 more
wiley   +1 more source

The effects of cross linking on collagen type 1 nanostructure and nanostructural response to uniaxial tension : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Engineering at Massey University, Manawatu, New Zealand [PDF]

, 2016
Reproduced by permission of The Royal Society of Chemistry: Kayed, H. R., Sizeland, K. H., Kirby, N., Hawley, A., Mudie, S. T., & Haverkamp, R. G. (2015). Collagen cross linking and fibril alignment in pericardium. RSC Advances, 5, 3611-3618.
Kayed, Hanan
core