Results 21 to 30 of about 4,476 (243)

Screening for primary immunodeficiency diseases by next‐generation sequencing in early life

open access: yesClinical & Translational Immunology, 2020
Objective We aimed to use next‐generation sequencing (NGS) for the early diagnosis of primary immunodeficiency diseases (PIDs) and define its effects on medical management for an infant cohort in early life.
Jinqiao Sun   +10 more
doaj   +1 more source

Is there clinical value in counting nucleated red blood cells and platelet indices in primary immunodeficiency disease?

open access: yesThe Turkish Journal of Pediatrics, 2017
Infections are the most common presentation of primary immunodeficiency diseases (PIDs). The increase of nucleated red blood cell (NRBC) count is interpreted as a systemic inflammatory response.
Nahide Ekici-Günay   +2 more
doaj   +1 more source

Connected Research: The Potential of the PID Graph

open access: yesPatterns, 2021
Summary: Persistent identifiers (PIDs) provide unique and long-lasting references to entities. They enable unique identification persistently over time and hence play a crucial role in supporting the FAIR (Findable, Accessible, Interoperable, Reusable ...
Helena Cousijn   +7 more
doaj   +1 more source

Quantitative diagnostic imaging of cancer tissues by using phosphor-integrated dots with ultra-high brightness

open access: yesScientific Reports, 2017
The quantitative sensitivity and dynamic range of conventional immunohistochemistry (IHC) with 3,3′-diaminobenzidine (IHC-DAB) used in pathological diagnosis in hospitals are poor, because enzyme activity can affect the IHC-DAB chromogenic reaction ...
Kohsuke Gonda   +21 more
doaj   +1 more source

Gene Therapies for Primary Immune Deficiencies

open access: yesFrontiers in Immunology, 2021
Gene therapy is an innovative treatment for Primary Immune Deficiencies (PIDs) that uses autologous hematopoietic stem cell transplantation to deliver stem cells with added or edited versions of the missing or malfunctioning gene that causes the PID ...
Lisa A. Kohn, Donald B. Kohn
doaj   +1 more source

Evolution or Revolution? PIDs for PID Users

open access: yes, 2020
The case for using PIDs extensively and consistently has more or less been made which begs the question as to why they are not implemented as completely as one might wish? The ARDC, through our National Information Infrastructure program, promotes the use of PID’s in the Australian research sector as a mechanism to link research concepts, funding ...
Simons, Natasha, Duncan, Ian
openaire   +1 more source

Uses of Next-Generation Sequencing Technologies for the Diagnosis of Primary Immunodeficiencies

open access: yesFrontiers in Immunology, 2017
Primary immunodeficiencies (PIDs) are genetic disorders impairing host immunity, leading to life-threatening infections, autoimmunity, and/or malignancies.
Michael Seleman   +3 more
doaj   +1 more source

Polypharmacy and potential inappropriate drug use in the elderly admitted to the general internal medicine outpatient clinic

open access: yesTurkish Journal of Internal Medicine, 2021
In this study, we aimed to investigate the rates of polypharmacy and potentially inappropriate drug (PID) use in elderly patients who admitted to General Internal Medicine Outpatient Clinic.
Celaleddin Demircan, Ulviyya Hasanzade
doaj   +1 more source

Smarter Sensors Through Machine Learning: Historical Insights and Emerging Trends across Sensor Technologies

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights how machine learning (ML) algorithms are employed to enhance sensor performance, focusing on gas and physical sensors such as haptic and strain devices. By addressing current bottlenecks and enabling simultaneous improvement of multiple metrics, these approaches pave the way toward next‐generation, real‐world sensor applications.
Kichul Lee   +17 more
wiley   +1 more source

Digital Actuation Control of Soft Robotic Origami With Self‐Folding Liquid Crystal Elastomer Hinges

open access: yesAdvanced Functional Materials, EarlyView.
Self‐folding soft‐rigid hybrid robotic origami is enabled by liquid crystal elastomer actuators with embedded Joule heating and closed‐loop digital control. Digitally addressable hinges provide reversible and programmable transitions between distinct folded states while maintaining actuation performance at high cycle counts (over 1500).
David C. Bershadsky   +3 more
wiley   +1 more source

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