Results 21 to 30 of about 158,569 (182)

Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size [PDF]

, 2016
Cytomegalovirus (CMV) infection is one of the most common persistent viral infections in humans worldwide and is epidemiologically associated with many adverse health consequences during aging.
A Harari, A Lelic, AM Simanek, AR Hersperger, AW Sylwester, C Courivaud, C Riou, E Derhovanessian, E Gimenez, E Sinclair, EJ Wherry, ET Roberts, F Bihl, F Kern, F Sallusto, G Makedonas, G Makedonas, G Pawelec, G Pawelec, GC Wang, GC Wang, IG Rodrigue-Gervais, J Cheng, J van Zanten, JM Fletcher, L Cicin-Sain, L Cicin-Sain, L Krol, ML Pita-Lopez, MR Betts, MR Wills, N Khan, P Trzonkowski, PA Darrah, Q Ouyang, R Lachmann, R Solana, R Vescovini, RA Seder, RA van Lier, S Cantisan, SA Migueles, SH Park, SR Hadrup, T Crough, V Appay, YL Chiu, YN Ji   +47 more
core   +1 more source

DCP-LA-Phosphatidylinositol and Its Enantiomer Exhibit Different Bioactivities

Cellular Physiology and Biochemistry, 2014
Background/Aims: The present study was conducted to understand biochemical and biological characteristics of the phosphatidylinositol (PI) derivative 1,2-O-bis-[8-{2-(2-pentyl-cyclopropylmethyl)-cyclopropyl}-octanoyl]-Sn-glycero-3-phosphatidyl-D-1 ...
Ayako Tsuchiya, Takeshi Kanno, Tadashi Shimizu, Syuhei Nakao, Akito Tanaka, Tomoyuki Nishizaki   +5 more
doaj   +1 more source

Exopolysaccharides From Streptococcus thermophilus ST538 Modulate the Antiviral Innate Immune Response in Porcine Intestinal Epitheliocytes

Frontiers in Microbiology, 2020
It was reported that exopolysaccharides (EPSs) from lactobacilli are able to differentially modulate mucosal antiviral immunity. Although research has described the ability of EPSs derived from Streptococcus thermophilus to modulate the mucosal immune ...
Hiroya Mizuno, Hiroya Mizuno, Kae Tomotsune, Kae Tomotsune, Md. Aminul Islam, Md. Aminul Islam, Ryutaro Funabashi, Ryutaro Funabashi, Leonardo Albarracin, Leonardo Albarracin, Leonardo Albarracin, Wakako Ikeda-Ohtsubo, Wakako Ikeda-Ohtsubo, Hisashi Aso, Hisashi Aso, Hideki Takahashi, Hideki Takahashi, Katsunori Kimura, Julio Villena, Julio Villena, Yasuko Sasaki, Haruki Kitazawa, Haruki Kitazawa   +22 more
doaj   +1 more source

Transcriptomic Analysis of the Innate Antiviral Immune Response in Porcine Intestinal Epithelial Cells: Influence of Immunobiotic Lactobacilli [PDF]

, 2017
Lactobacillus rhamnosus CRL1505 and Lactobacillus plantarum CRL1506 are immunobiotic strains able to increase protection against viral intestinal infections as demonstrated in animal models and humans.
Haruki Kitazawa, Hikaru Iida, Hisakazu Kobayashi, Hisashi Aso, Julio Villena, Leonardo Albarracin, Nana Sato, Susana Alvarez, Susana Salva, Tomonori Nochi   +9 more
core   +2 more sources

Selection of Immunobiotic Ligilactobacillus salivarius Strains from the Intestinal Tract of Wakame-Fed Pigs: Functional and Genomic Studies

Microorganisms, 2020
In this article, Ligilactobacillus salivarius FFIG strains, isolated from the intestinal tract of wakame-fed pigs, are characterized according to their potential probiotic properties.
Binghui Zhou, Leonardo Albarracin, Yuhki Indo, Lorena Arce, Yuki Masumizu, Mikado Tomokiyo, Md. Aminul Islam, Valeria Garcia-Castillo, Wakako Ikeda-Ohtsubo, Tomonori Nochi, Hidetoshi Morita, Hideki Takahashi, Shoichiro Kurata, Julio Villena, Haruki Kitazawa   +14 more
doaj   +1 more source

Lactiplantibacillus plantarum Strains Modulate Intestinal Innate Immune Response and Increase Resistance to Enterotoxigenic Escherichia coli Infection

Microorganisms, 2022
Currently, probiotic bacteria with not transferable antibiotic resistance represent a sustainable strategy for the treatment and prevention of enterotoxigenic Escherichia coli (ETEC) in farm animals.
Ayelen Baillo, Julio Villena, Leonardo Albarracín, Mikado Tomokiyo, Mariano Elean, Kohtaro Fukuyama, Sandra Quilodrán-Vega, Silvina Fadda, Haruki Kitazawa   +8 more
doaj   +1 more source

Tumor-associated and immunochemotherapy-dependent long-term alterations of the peripheral blood NK cell compartment in DLBCL patients [PDF]

, 2015
Natural Killer (NK) cells are a key component of tumor immunosurveillance and thus play an important role in rituximab-dependent killing of lymphoma cells via an antibody-dependent cellular cytotoxicity (ADCC) mechanism.
Battella, Simone, Cecere, Francesca, DI NAPOLI, Arianna, Eleonora, Alma, LA SCALEIA, Raffaella, M., Christina Cox, Mainiero, Fabrizio, Monarca, Bruno, Palmieri, Gabriella, Pelliccia, Sabrina, Porzia, Alessandra, Ruco, Luigi, Santoni, Angela, Zingoni, Alessandra   +13 more
core   +1 more source

A novel function for the Caenorhabditis elegans torsin OOC-5 in nucleoporin localization and nuclear import. [PDF]

, 2015
Torsin proteins are AAA+ ATPases that localize to the endoplasmic reticular/nuclear envelope (ER/NE) lumen. A mutation that markedly impairs torsinA function causes the CNS disorder DYT1 dystonia. Abnormalities of NE membranes have been linked to torsinA
Dauer, William T, Hall, David H, Nguyen, Ken CQ, Rose, Lesilee S, VanGompel, Michael JW   +4 more
core   +2 more sources

Query-points visibility constraint minimum link paths in simple polygons

, 2021
We study the query version of constrained minimum link paths between two points inside a simple polygon $P$ with $n$ vertices such that there is at least one point on the path, visible from a query point.
Charkari, Nasrollah Moghaddam, Zarrabi, Mohammad Reza   +1 more
core   +1 more source

Immunobiotic lactic acid bacteria beneficially regulate immune response triggered by poly(I:C) in porcine intestinal epithelial cells

Veterinary Research, 2011
This study analyzed the functional expression of TLR3 in various gastrointestinal tissues from adult swine and shows that TLR3 is expressed preferentially in intestinal epithelial cells (IEC), CD172a+CD11R1high and CD4+ cells from ileal Peyer's patches ...
Hosoya Shoichi, Villena Julio, Shimazu Tomoyuki, Tohno Masanori, Fujie Hitomi, Chiba Eriko, Shimosato Takeshi, Aso Hisashi, Suda Yoshihito, Kawai Yasushi, Saito Tadao, Alvarez Susana, Ikegami Shuji, Itoh Hiroyuki, Kitazawa Haruki   +14 more
doaj   +1 more source