Results 31 to 40 of about 158,569 (182)

Onion Curve: A Space Filling Curve with Near-Optimal Clustering [PDF]

open access: yes, 2018
Space filling curves (SFCs) are widely used in the design of indexes for spatial and temporal data. Clustering is a key metric for an SFC, that measures how well the curve preserves locality in moving from higher dimensions to a single dimension.
Nguyen, Cuong   +3 more
core   +4 more sources

Efficient Selection of New Immunobiotic Strains With Antiviral Effects in Local and Distal Mucosal Sites by Using Porcine Intestinal Epitheliocytes

open access: yesFrontiers in Immunology, 2020
Previously, we evaluated the effect of the immunobiotic strain Lactobacillus rhamnosus CRL1505 on the transcriptomic response of porcine intestinal epithelial (PIE) cells triggered by the challenge with the Toll-like receptor 3 (TLR-3) agonist poly(I:C ...
Leonardo Albarracin   +16 more
doaj   +1 more source

Paraimmunobiotic Bifidobacteria Modulate the Expression Patterns of Peptidoglycan Recognition Proteins in Porcine Intestinal Epitheliocytes and Antigen Presenting Cells

open access: yesCells, 2019
Peptidoglycan recognition proteins (PGLYRPs) are a family of pattern recognition receptors (PRRs) that are able to induce innate immune responses through their binding to peptidoglycan (PGN), lipopolysaccharide, or lipoteichoic acid, or by interacting ...
Hikaru Iida   +16 more
doaj   +1 more source

The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells. [PDF]

open access: yes, 2017
Transfer RNAs (tRNAs) function in translational machinery and further serves as a source of short non-coding RNAs (ncRNAs). tRNA-derived ncRNAs show differential expression profiles and play roles in many biological processes beyond translation ...
Honda, Shozo   +5 more
core   +2 more sources

Genomic Characterization of Lactobacillus delbrueckii TUA4408L and Evaluation of the Antiviral Activities of its Extracellular Polysaccharides in Porcine Intestinal Epithelial Cells

open access: yesFrontiers in Immunology, 2018
In lactic acid bacteria, the synthesis of exopolysaccharides (EPS) has been associated with some favorable technological properties as well as health-promoting benefits.
Paulraj Kanmani   +26 more
doaj   +1 more source

Immunobiotic Lactobacillus jensenii TL2937 Alleviates Dextran Sodium Sulfate-Induced Colitis by Differentially Modulating the Transcriptomic Response of Intestinal Epithelial Cells

open access: yesFrontiers in Immunology, 2020
Immunobiotics have emerged as a promising intervention to alleviate intestinal damage in inflammatory bowel disease (IBD). However, the beneficial properties of immunobiotics are strain dependent and, therefore, each strain has to be evaluated in order ...
Nana Sato   +22 more
doaj   +1 more source

Chemotherapy accelerates immune-senescence and functional impairments of Vδ2pos T cells in elderly patients affected by liver metastatic colorectal cancer. [PDF]

open access: yes, 2019
Human (gamma delta) γδ T cells are unconventional innate-like lymphocytes displaying a broad array of anti-tumor activities with promising perspectives in cancer immunotherapy.
Bruni E   +9 more
core   +1 more source

Evaluating cellular polyfunctionality with a novel polyfunctionality index. [PDF]

open access: yesPLoS ONE, 2012
Functional evaluation of naturally occurring or vaccination-induced T cell responses in mice, men and monkeys has in recent years advanced from single-parameter (e.g. IFN-γ-secretion) to much more complex multidimensional measurements.
Martin Larsen   +5 more
doaj   +1 more source

Propofol Inhibits Proliferation and Augments the Anti-Tumor Effect of Doxorubicin and Paclitaxel Partly Through Promoting Ferroptosis in Triple-Negative Breast Cancer Cells

open access: yesFrontiers in Oncology, 2022
BackgroundTriple-negative breast cancer (TNBC) is relatively common in women and is associated with a poor prognosis after surgery and adjuvant chemotherapy.
Chen Sun   +11 more
doaj   +1 more source

Hypercellular graphs: partial cubes without $Q_3^-$ as partial cube minor [PDF]

open access: yes, 2019
We investigate the structure of isometric subgraphs of hypercubes (i.e., partial cubes) which do not contain finite convex subgraphs contractible to the 3-cube minus one vertex $Q^-_3$ (here contraction means contracting the edges corresponding to the ...
Chepoi, Victor   +2 more
core   +2 more sources

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