Results 111 to 120 of about 4,014 (160)

Decoding the mechanotransduction role of Piezo2 in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a low and stagnant survival rate of 12.5%, largely due to limited treatment options, therapeutic resistance, and relapse driven by cancer stem cells (CSCs).
Tran, L
core  

Piezo channels in physical field therapy: From mechanotransduction mechanisms to bioelectromagnetic modulation and biomedical applications. [PDF]

Mechanobiol Med
Li B, Kang HM, Pan WD, Li Y.
europepmc   +1 more source

ROS-responsive nanoplatform-mediated targeted intranasal delivery of Piezo2 siRNA for the treatment of trigeminal neuralgia. [PDF]

Mater Today Bio
Wang Y, Zhao L, Chen J, Cao P, Li Y, Wang Q, Xiang J, Chen S, Liu S, Zhang H, Luo D, Lin M, Wang F.   +12 more
europepmc   +1 more source

Painful neuromas exhibit axonal phenotypic shift via nociceptive and mechanosensitive marker up-regulation. [PDF]

PNAS Nexus
Tereshenko V, Raasveld FV, Hwang CD, Hussey MR, Johnston B, Valerio IL, Austen WG, Wainger BJ, Renthal W, Eberlin KR.   +9 more
europepmc   +1 more source

Sympathetic Overactivation Drives Neurogenic Alveolar Epithelial Pyroptosis via the PIEZO2-ER Stress Pathway in Acute Lung Injury Following Intracerebral Hemorrhage. [PDF]

CNS Neurosci Ther
Han S, Wang Z, Zheng Q, Guo F, Xiao Y, Wang Z, Huang T, Liang Y, Yan B, Gao J.   +9 more
europepmc   +1 more source

Piezo2-Initiated Ultrafast Signaling and Its Acquired Channelopathy in Light of Quantum Gravity Theory. [PDF]

Int J Mol Sci
Sonkodi B.
europepmc   +1 more source

Exploratory Immunohistochemical Mapping of Mechanosensitivity-Associated Ion Channel Proteins in Terminal Glial Cells of Human Meissner and Pacinian Corpuscles. [PDF]

Int J Mol Sci
Amigo I, García-Mesa Y, Cuendias P, Feito J, García-Suárez O, Abreu-Velez AM, Suazo I, Vega JA.   +7 more
europepmc   +1 more source

The Role of Piezo Ion Channels in Pulmonary Hypertension. [PDF]

Pulm Circ
Chen K, Li L, Huang Y, Ye L, Wang Y, Zhang Z, Hang C, Li Q, Cao Q, Du L.   +9 more
europepmc   +1 more source

Docking-score landscapes shape active-learning performance across Vina, Glide, and SILCS. [PDF]

J Comput Aided Mol Des
Chung J, Bhatt A, Levine JE, Lin YC, Zhao M, MacKerell AD, Jo S, Kosaraju SC, Luo YL.   +8 more
europepmc   +1 more source

System-level synchronization and subtype-specific modules govern brain-wide serotonin axon innervation. [PDF]

Proc Natl Acad Sci U S A
Adams AMJ, Wu KLK, Li Z, Li P, Pan H, Huang Z, Migliarini S, Dear R, Sun B, Chan ZC, Liang J, Li H, Vértes PE, Pasqualetti M, Isakova A, Ren J.   +15 more
europepmc   +1 more source