Results 121 to 130 of about 5,132 (198)

Novel mutations in TPM2 and PIEZO2 are responsible for distal arthrogryposis (DA) 2B and mild DA in two Chinese families

BMC Medical Genetics, 2018
Background Distal arthrogryposis (DA) is a group of clinically and genetically heterogeneous disorders that involve multiple congenital limb contractures and comprise at least 10 clinical subtypes.
Shan Li, Yi You, Jinsong Gao, Bin Mao, Yixuan Cao, Xiuli Zhao, Xue Zhang   +6 more
doaj   +1 more source

Chronic femoral artery ligation exaggerates the pressor and sympathetic nerve responses during dynamic skeletal muscle stretch in decerebrate rats [PDF]

Master of ScienceDepartment of KinesiologySteven CoppMechanical and metabolic signals arising during skeletal muscle contraction reflexly increase sympathetic nerve activity and blood pressure (i.e., the exercise pressor reflex).
Kempf, Evan Alexander
core  

MyGene2 automated match report: PIEZO2

, 2016
MyGene2.org is free, public, searchable & browsable website. Families with rare genetic conditions, clinicians, and researchers families who are interested in sharing health and genetic information can create MyGene2 profiles and use these to connect with other families, clinicians, and researchers who may have or be studying the same condition. If
openaire   +1 more source

Role of Piezo2 in Schwann Cell Volume Regulation and Its Impact on Neurotrophic Release Regulation

Cellular Physiology and Biochemistry
Background/Aims: Tactile perception relies on mechanoreceptors and nerve fibers, including c-fibers, Aβ-fibers and Aδ-fibers. Schwann cells (SCs) play a crucial role in supporting nerve fibers, with non-myelinating SCs enwrapping c-fibers and myelinating
Chawapun Suttinont, Moe Tsutsumi, Tomohiro Numata, Kaori Sato-Numata, Mamiko Yano, Katsuyuki Maeno   +5 more
doaj   +1 more source

Fibroblasts profiling in scarring trachoma identifies IL-6 as a functional component of a fibroblast-macrophage pro-fibrotic and pro-inflammatory feedback loop [PDF]

, 2016
Trachoma is a conjunctiva scarring disease, which is the leading infectious cause of blindness worldwide. Yet, the molecular mechanisms underlying progressive fibrosis in trachoma are unknown. To investigate the contribution of local resident fibroblasts
Bailly, M, Burton, MJ, Ezra, DG, Kechagia, JZ   +3 more
core  

mpECs with high Piezo2 expression promote fracture healing by driving angiogenesis through the Notch signaling pathway

BMC Musculoskeletal Disorders
Fractures will impair or disrupt angiogenesis, resulting in delayed union or non-union. Exploring angiogenic signaling molecules and related pathways can promote fracture healing.
Lingfeng He, Fanyong Gong, Jiangyong Wang, Yi Huang, Haifeng Wang   +4 more
doaj   +1 more source

Piezo Mediates the Mechanosensation and Injury-Repair of Pulpo-Dentinal Complex

International Dental Journal
Objectives: The aim of this research was to investigate the functions of Piezo channels in dentin defect, including mechanical signalling and odontoblast responses.
Xiaoqiao Xu, Yi Guo, Peiqi Liu, Hui Zhang, Yijie Wang, Zhen Li, Yukun Mei, Lin Niu, Ruirui Liu   +8 more
doaj   +1 more source

A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites. [PDF]

, 2019
Interactions between epithelial cells and neurons influence a range of sensory modalities including taste, touch, and smell. Vertebrate and invertebrate epidermal cells ensheath peripheral arbors of somatosensory neurons, including nociceptors, yet the ...
Clanton, Joshua A, Cronan, Mark R, Jiang, Nan, Kim, Hyeon-Jin, Luedke, Kory P, Parker, Edward D, Parrish, Jay Z, Rasmussen, Jeffrey P, Rosenberg, Marci F, Sagasti, Alvaro, Vaughan, Joshua C   +10 more
core  

Quantitative and functional post-translational modification proteomics reveals that TREPH1 plays a role in plant thigmomorphogenesis

, 2018
Plants can sense both intracellular and extracellular mechanical forces and can respond through morphological changes. The signaling components responsible for mechanotransduction of the touch response are largely unknown.
Braam, Janet, Chehab, E. Wassim, Dai, Chen, Li, Ning, Liu, Jun, Liu, Shichang, Qing, Dongjin, Ren, Feng, Wang, Kai, Wu, Madeline, Yang, Zhu, Zhang, Weiping, Zheng, Qingsong   +12 more
core   +2 more sources

Expression patterns of mechanosensitive ion channel PIEZOs in irreversible pulpitis

BMC Oral Health
Background Mechanosensitive ion channel PIEZOs have been widely reported to involve inflammation and pain. This study aimed to clarify expression patterns of PIEZOs and their potential relations to irreversible pulpitis. Materials and methods Normal pulp
Wenying Yang, Lu Lin, Shucheng Hu, Bin Jiang, Ruhan Yang, Weijun Yu, Jiaqi Tang, Dan Zhao, Yuting Gu, Min Jin, Jin Li, Eryi Lu   +11 more
doaj   +1 more source