Results 1 to 10 of about 77,731 (192)
Idiopathic polypoidal choroidal vasculopathy [PDF]
Background. Idiopathic polypoidal choroidal vasculopathy (IPCV) is uncommon condition. It is considered to be a variant of neovascular age-related macular degeneration, but it can be also found in younger patients. Case report.
Cekić Sonja +3 more
doaj +3 more sources
Comparison of retinal pigment epithelium cell preparations from the bovine eye [PDF]
Retinal pigment epithelium (RPE) cells were collected from bovine eyes using a new method. The cells were harvested by vortexing the RPE and underlying choroid in 0.05 M citrate phosphate buffer, pH 5. RPE cells recovered by this method were compared to a standard method by microscopic examination of cell integrity, estimation of total protein, and ...
S R, Sanders-Sanchez +2 more
openaire +2 more sources
MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo [PDF]
Purpose: Milk fat globule-epidermal growth factor-factor VIII (MFGE8) is necessary for diurnal outer segment phagocytosis and promotes VEGF-dependent neovascularization.
A Swaroop +52 more
core +15 more sources
The other pigment cell: specification and development of the pigmented epithelium of the vertebrate eye [PDF]
SummaryVertebrate retinal pigment epithelium (RPE) cells are derived from the multipotent optic neuroepithelium, develop in close proximity to the retina, and are indispensible for eye organogenesis and vision. Recent advances in our understanding of RPE development provide evidence for how critical signaling factors operating in dorso‐ventral and ...
Kapil, Bharti +4 more
openaire +2 more sources
Antioxidant Defenses in the Human Eye: A Focus on Metallothioneins
The human eye, the highly specialized organ of vision, is greatly influenced by oxidants of endogenous and exogenous origin. Oxidative stress affects all structures of the human eye with special emphasis on the ocular surface, the lens, the retina and ...
Ana Álvarez-Barrios +5 more
doaj +1 more source
PurposeTo determine whether age-related macular degeneration (AMD) severity or the frequency of retinal pigment epithelium mitochondrial DNA lesions differ in human donor eyes that have undergone cataract surgery compared to phakic eyes.MethodsEyes from ...
Karen R Armbrust +6 more
doaj +1 more source
We report the case of a 57-year-old female patient who presented with defective vision in the right eye due to large hemorrhagic pigment epithelial detachment with subretinal hemorrhage near the arcades with scattered retinal pigment epithelium (RPE ...
Shreyas Shah +3 more
doaj +1 more source
Dual roles of the retinal pigment epithelium and lens in cavefish eye degeneration [PDF]
Abstract Astyanax mexicanus consists of two forms, a sighted surface dwelling form (surface fish) and a blind cave‐dwelling form (cavefish). Embryonic eyes are initially formed in cavefish but they are subsequently arrested in growth and degenerate during larval development.
Li Ma +4 more
openaire +3 more sources
Type 3 Neovascularization Associated with Retinitis Pigmentosa
Purpose: To report a case of type 3 neovascular lesion in a patient with retinitis pigmentosa (RP) complicated by macular edema. Case Report: A 78-year-old man with a long follow-up for RP was referred for painless visual acuity decrease in the right eye.
Jihene Sayadi +3 more
doaj +1 more source
Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins [PDF]
Background Mutations in pre-mRNA splicing factor PRPF31 can lead to retinitis pigmentosa (RP). Although the exact disease mechanism remains unknown, it has been hypothesized that haploinsufficiency might be involved in the ...
Aramburu, Ana +13 more
core +2 more sources

