Results 31 to 40 of about 2,749,048 (351)

Co occurrance of Macular Telangiectasia type 2 with hemorrhagic polypoidal choroidal vasculopathy and response to anti-vascular endothelial growth factor

Oman Journal of Ophthalmology, 2023
We report the case of a 57-year-old female patient who presented with defective vision in the right eye due to large hemorrhagic pigment epithelial detachment with subretinal hemorrhage near the arcades with scattered retinal pigment epithelium (RPE ...
Shreyas Shah, George J Manayath, Shruthi Gajula, Venkatapathy Narendran   +3 more
doaj   +1 more source

Presumed Adenocarcinoma of the Retinal Pigment Epithelium in a Blind Eye With a Staphyloma [PDF]

Archives of Ophthalmology, 1998
The retinal pigment epithelium (RPE) can undergo reactive hyperplasia and metaplasia following a variety of ocular insults. However, true neoplasms of the RPE are rare. We report a case of a papillary adenocarcinoma of the RPE arising in the blind staphylomatous right eye of a 79-year-old woman with a long history of bilateral posterior staphylomas who
Chaim Edelstein, Jerry A. Shields, Carol L. Shields, Ralph C. Eagle   +3 more
openaire   +3 more sources

PAF‐induced inflammatory and immuno‐allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects

BioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022
Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley   +1 more source

Type 3 Neovascularization Associated with Retinitis Pigmentosa

Case Reports in Ophthalmology, 2017
Purpose: To report a case of type 3 neovascular lesion in a patient with retinitis pigmentosa (RP) complicated by macular edema. Case Report: A 78-year-old man with a long follow-up for RP was referred for painless visual acuity decrease in the right eye.
Jihene Sayadi, Alexandra Miere, Eric H. Souied, Salomon Y. Cohen   +3 more
doaj   +1 more source

Eye development: a view from the retina pigmented epithelium

BioEssays, 2004
AbstractThe retina pigment epithelium (RPE) is a highly specialised epithelium that serves as a multifunctional and indispensable component of the vertebrate eye. Although a great deal of attention has been paid to its transdifferentiation capabilities and its ancillary functions in neural retina development, little is known about the molecular ...
Martínez-Morales, Juan Ramón, Rodrigo Castro, M. Isabel, Bovolenta, Paola   +2 more
openaire   +4 more sources

Methods for culturing retinal pigment epithelial cells: a review of current protocols and future recommendations

Journal of Tissue Engineering, 2016
The retinal pigment epithelium is an important part of the vertebrate eye, particularly in studying the causes and possible treatment of age-related macular degeneration.
Aaron H Fronk, Elizabeth Vargis
doaj   +1 more source

Near-infrared fundus autoflorescence imaging in solar retinopathy

GMS Ophthalmology Cases, 2017
Solar retinopathy is a rare clinical entity caused by photochemical damage to the retinal pigment epithelium layer and photoreceptors of the fovea. Here we describe a case of a 33-year-old female patient diagnosed by near-infrared fundus autofluorescence
Czepita, Maciej, Machalińska, Anna, Czepita, Damian   +2 more
doaj   +1 more source

Serpentine retinal pigment epithelial tear

Taiwan Journal of Ophthalmology, 2021
We report a case of retinal pigment epithelial tear in a patient with peripheral exudative hemorrhagic chorioretinopathy (PEHCR). A 60-year-old diabetic female presented with left eye metamorphopsia. Fundus examination showed bilateral peripheral retinal
Aditya Maitray, Piyush Kohli, Naresh Babu   +2 more
doaj   +1 more source

Retinal regions shape human and murine Müller cell proteome profile and functionality

Glia, Volume 71, Issue 2, Page 391-414, February 2023., 2023
Main Points We defined Müller cells heterogeneity in the macular and peripheral human retina. Signaling pathways shaping this glial heterogeneity include proteins important for interaction with vesicular secretion, extracellular matrix and cell adhesion.
Lew Kaplan, Corinne Drexler, Anna M. Pfaller, Santra Brenna, Kirsten A. Wunderlich, Andrea Dimitracopoulos, Juliane Merl‐Pham, Maria‐Theresa Perez, Ursula Schlötzer‐Schrehardt, Volker Enzmann, Marijana Samardzija, Berta Puig, Peter Fuchs, Kristian Franze, Stefanie M. Hauck, Antje Grosche   +15 more
wiley   +1 more source

Functional characterization of a novel TP53RK mutation identified in a family with Galloway–Mowat syndrome

Human Mutation, Volume 43, Issue 12, Page 1866-1871, December 2022., 2022
Abstract Galloway–Mowat syndrome (GAMOS) is a very rare condition characterized by early‐onset nephrotic syndrome and microcephaly with variable neurologic features. While considerable genetic heterogeneity of GAMOS has been identified, the majority of cases are caused by pathogenic variants in genes encoding the four components of the Kinase ...
Ernestine Treimer, Tugba Kalayci, Sven Schumann, Ilknur Suer, Sara Greco, Denny Schanze, Michael J. Schmeisser, Susanne J. Kühl, Martin Zenker   +8 more
wiley   +1 more source