Results 41 to 50 of about 38,345 (280)

Pigmentation disorders, causes and risks. Available products for treatment and prevention in pharmacies

, 2023
FarmācijaVeselības aprūpePharmacyHealth CarePētnieciskais darbs “Pigmentācijas traucējumi, iemesli un riski. Ārstēšanai un profilaksei pieejamie līdzekļi aptieku sortimentā” tika izstrādāts no 2022. gada oktobra līdz 2023.
Tatjana Obžina
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Synthesis of Human Skin Pigmentation Disorders

, 2017
Changes in the human pigmentary system can lead to imbalances in the distribution of melanin in the skin resulting in artefacts known as pigmented lesions.
Barros, R. S., Walter, M.
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hypomelanosis of Ito–Brain Melanin Deposition on Magnetic Resonance Imaging: A Preliminary Hypothesis Based on Two Pediatric Cases [PDF]

Annals of Child Neurology
To investigate brain melanin deposition on magnetic resonance imaging (MRI) in hypomelanosis of Ito (HI) by presenting two clinical cases and reviewing relevant literature.
Roshwanth Arbujin, Sameer Peer, Balachandar Vellingiri, Madhu S. Gaddigoudar, Pawan Kumar Ghanghoriya, Arvinder Wander   +5 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Phototherapy as an effective treatment for Majocchi's disease - Case report [PDF]

Anais Brasileiros de Dermatologia, 2015
Pigmented purpuric dermatoses are chronic and relapsing disorders characterized by a symmetrical rash of petechial and pigmentary macules, mainly confined to the lower limbs. Purpura annularis telangiectodes of Majocchi is a
Tapan Kumar Dhali, Monica Chahar, Mohammad Asad Haroon   +2 more
doaj   +1 more source

Pigmentation disorders and dyschromias [PDF]

, 2015
Boja kože odraz je mješavine četiriju pigmenata: endogeno stvorenog smeđeg melanina, egzogenoga žutog karotena te reduciranoga plavog i oksidiranoga crvenog hemoglobina. Glavna determinanta boje kože je melanin. Sinteza melanina odvija se u melanocitima,
Čoga, Matilda
core  

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Solid Harmonic Wavelet Bispectrum for Image Analysis

Advanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown, Mathilda Avirett‐Mackenzie, Carolin Villforth, Georgios Exarchakis   +3 more
wiley   +1 more source