Comparison of pilocarpine‐ versus exercise‐induced sweat sodium concentration across exercise intensities in trained athletes [PDF]
Physiological ReportsPilocarpine‐induced sweat testing offers a laboratory‐based method for assessing sweat composition, but its comparability to exercise sweating remains unclear.
Christopher T. Harris +4 more
doaj +3 more sources
Role of nitric oxide of the median preoptic nucleus (MnPO) in the alterations of salivary flow, arterial pressure and heart rate induced by injection of pilocarpine into the MnPO and intraperitoneally [PDF]
Brazilian Journal of Medical and Biological Research, 2003 We investigated the effect of L-NAME, a nitric oxide (NO) inhibitor and sodium nitroprusside (SNP), an NO-donating agent, on pilocarpine-induced alterations in salivary flow, mean arterial blood pressure (MAP) and heart rate (HR) in rats.
Wilson A. Saad +7 more
doaj +2 more sources
Modulation of the Thrombin Pathway Restores LTP in a Pilocarpine Mice Model of Status Epilepticus [PDF]
Frontiers in Cellular Neuroscience, 2022 BackgroundStatus epilepticus (SE) leads to memory impairment following a seizure, attributed to long-term potentiation (LTP) reduction. Thrombin, a coagulation factor that activates protease-activated receptor 1 (PAR1) is involved in cognitive impairment
Efrat Shavit-Stein +14 more
doaj +2 more sources
Modulation of pilocarpine-induced seizures by cannabinoid receptor 1. [PDF]
PLoS ONE, 2014 Administration of the muscarinic agonist pilocarpine is commonly used to induce seizures in rodents for the study of epilepsy. Activation of muscarinic receptors has been previously shown to increase the production of endocannabinoids in the brain ...
Rebecca L Kow +5 more
doaj +3 more sources
Validation of Smart Nanoparticles as Controlled Drug Delivery Systems: Loading and pH-Dependent Release of Pilocarpine [PDF]
, 2018 Micelles are good devices for use as controlled drug delivery systems because they exhibit the ability to protect the encapsulated substance from the routes of degradation until they reach the site of action.
Galbis Fuster, Elsa +6 more
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Effect of Pilocarpine Mouthwash on Salivary Flow Rate in Patients with Xerostomia: A Systematic Review and Meta-Analysis [PDF]
Journal of Dentistry, 2023 Statement of the Problem: Xerostomia is a subjective sensation of dry mouth considered as a complex state affecting multiple oral functions. Pilocarpine may be a useful medication for the treatment of xerostomia, but its side effects limit its use under ...
Katayoun Katebi +4 more
doaj +1 more source
Dilute pilocarpine test for diagnosis of Adie’s tonic pupil
Scientific Reports, 2021 We have compared the diagnostic ability of different concentrations of 0.125% and 0.0625% dilute pilocarpine for detecting denervation supersensitivity in unilateral Adie’s tonic pupil.
Yung-Ju Yoo +2 more
doaj +1 more source
Bilateral vitreomacular traction syndrome associated with topical pilocarpine 1% ophthalmic solution
American Journal of Ophthalmology Case Reports, 2023 To describe a case of transient bilateral vitreomacular traction syndrome associated with topical 1% pilocarpine ophthalmic solution in both eyes as a treatment for advanced glaucoma. Observations: Spectral-domain OCT demonstrated bilateral vitreomacular
Radames Rios Gonzalez +2 more
doaj +1 more source
BMC Oral Health, 2022 Aims & background Pilocarpine is an accepted treatment for xerostomia, but limited research has been conducted on the oral, topical form. The present study aimed to compare the effects of 1 and 2% pilocarpine mouthwash on xerostomic participants. Methods
Babak Motamed +5 more
doaj +1 more source
Substantial outcome improvement using a refined pilocarpine mouse model of temporal lobe epilepsy
Neurobiology of Disease, 2021 Systemic pilocarpine treatment is one of the most reliable means of inducing temporal lobe epilepsy (TLE). However, the traditional pilocarpine injection protocol using mice was associated with a high death rate, possibly because of cardiorespiratory ...
Alexandre Vigier +4 more
doaj +1 more source