Results 31 to 40 of about 17,022 (157)

The Effect of 1% Pilocarpine Mouthwash on Salivary Flow Rate in Patients with Radiation-Induced Xerostomia: A Double-Blind Randomized Clinical Trial [PDF]

Middle East Journal of Cancer
Background: Radiation-induced hyposalivation is a common complication of radiotherapy for head and neck cancers. The most commonly prescribed medication for hyposalivation is pilocarpine. However, due to the numerous systemic side-effects associated with
Paria Motahari, Farzaneh Pakdel, Nastaran Hashemzadeh, Farid Heydari, Reza Eghdam Zamiri, Katayoun Katebi   +5 more
doaj   +1 more source

A Review on the Role of Pilocarpine on the Management of Xerostomia and the Importance of the Topical Administration Systems Development

Pharmaceuticals, 2022
Xerostomia is linked to an increased risk of dental caries, oral fungal infections, and speaking/swallowing difficulties, factors that may significantly degrade patients’ life, socially- or emotionally-wise.
Afroditi Kapourani, Konstantinos N. Kontogiannopoulos, Panagiotis Barmpalexis   +2 more
doaj   +1 more source

The inhibitory effects of Npas4 on seizures in pilocarpine-induced epileptic rats.

PLoS ONE, 2014
To explore the effects of neuronal Per-Arnt-Sim domain protein 4 (Npas4) on seizures in pilocarpine-induced epileptic rats, Npas4 expression was detected by double-label immunofluorescence, immunohistochemistry, and Western blotting in the brains of ...
Dan Wang, Min Ren, Jiamei Guo, Guang Yang, Xianghua Long, Rong Hu, Wenjing Shen, Xuefeng Wang, Kebin Zeng   +8 more
doaj   +1 more source

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source

Printed Wearable Sweat Rate Sensor for Continuous In Situ Perspiration Measurement

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
A wireless wearable sweat rate sensor system is presented, featuring digital 3D direct‐write printing on a flexible substrate with microfluidic layers for continuous, real‐time monitoring. Printed encapsulated metal electrodes are used for capacitance measurements, achieving high sensitivity (0.01 μL min−1) while maintaining a compact and lightweight ...
Mohammad Shafiqul Islam, Sangwon Cha, Md Farhad Hassan, Wenxin Cai, Tahsin Sejat Saniat, Cedar Rose Leach, Yasser Khan   +6 more
wiley   +1 more source

Inroads into epilepsy through high‐frequency oscillations: Achievements and benchmark areas for improvement

Epilepsia, EarlyView.
Abstract High‐frequency oscillations (HFOs) were discovered more than 20 years ago, and since then they have been studied intensively in the context of epilepsy. HFOs encompass a broad spectrum of oscillations, typically ranging from 80 Hz to several kHz, that include both normal and pathological oscillations, documented in people with epilepsy and ...
Christos Panagiotis Lisgaras, Birgit Frauscher, Jean Gotman, Julia Jacobs, Philippe Kahane, Richard J. Staba, Maeike Zijlmans   +6 more
wiley   +1 more source

The effect of pilocarpine on dental caries in patients with primary Sjögren’s syndrome: a database prospective cohort study

Arthritis Research & Therapy, 2019
Background Primary Sjögren’s syndrome (pSS) is associated with dental caries. Pilocarpine, a salivary stimulant, can improve the amount and flow rate of saliva in patients with pSS.
Chung-Yuan Hsu, Kuo-Chun Hung, Ming-Shyan Lin, Chi-Hua Ko, Yu-Sheng Lin, Tien-Hsing Chen, Chun-Yu Lin, Ying-Chou Chen   +7 more
doaj   +1 more source

Does pilocarpine-induced epilepsy in adult rats require status epilepticus? [PDF]

PLoS ONE, 2009
Pilocarpine-induced seizures in rats provide a widely animal model of temporal lobe epilepsy. Some evidences reported in the literature suggest that at least 1 h of status epilepticus (SE) is required to produce subsequent chronic phase, due to the SE ...
Graciela Navarro Mora, Placido Bramanti, Francesco Osculati, Asmaa Chakir, Elena Nicolato, Pasquina Marzola, Andrea Sbarbati, Paolo Francesco Fabene   +7 more
doaj   +1 more source

Insulin‐like growth factor 1 receptor correlates with verbal memory in ILAE type 2 hippocampal sclerosis

Epilepsia, EarlyView.
Abstract Objective Long‐term memory deficits are often seen in patients with temporal lobe epilepsy (TLE). Recently, studies showed that patients with hippocampal sclerosis (HS) type 2, which presents with severe neuron loss in CA1 only, performed within the normal range. However, up to 30% of HS type 2 cases have memory deficits.
Henrique Cruz, Amauri Batista de Oliveira‐Júnior, André Fernando Garcia Cortez, Ricardo Lutzky Saute, Ricardo Silva Centeno, Joao Norberto Stávale, Mirian Salvadori Bittar Guaranha, Elza Marcia Targas Yacubian, Esper Abrão Cavalheiro, Joao Pereira Leite, Jose Eduardo Peixoto‐Santos   +10 more
wiley   +1 more source

Effect of Silibinin in Lowering the Intraocular Pressure in Normotensive Rabbits: Interaction with Pilocarpine and Cyclopentolate

Iraqi Journal of Pharmaceutical Sciences, 2017
Previous data indicated the effectiveness of silibinin as intraocular pressure (IOP) - lowering agent.  The present study was performed to evaluate the interaction of silibinin with pilocarpine or cyclopentolate in lowering IOP in normotensive rabbits ...
Saad A. Hussain, Haider M. Mohammed, Munaf H. Abdulrazzaq, Ahmed T. Numan   +3 more
doaj   +3 more sources