Results 111 to 120 of about 519,483 (296)

THE PINEAL GLAND, ESPECIALLY IN RELATION TO THE PROBLEM ON ITS SUPPOSED SIGNIFICANCE IN SEXUAL DEVELOPMENT

open access: yes, 1923
The pineal gland, glandula pinealis, corpus pineale, epiphysis cerebri or conarium is an organ, the function of which has remained unknown up to the present day.
K. Krabbe
semanticscholar   +1 more source

Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland

open access: yesPLoS Biology, 2012
Dopamine and adrenergic receptor complexes form under a circadian-regulated cycle and directly modulate melatonin synthesis and release from the pineal gland.
Sergio González   +12 more
semanticscholar   +1 more source

Molecular profile of adult primary leptomeningeal gliomatosis aligns with glioblastoma, IDH‐wildtype

open access: yesBrain Pathology, Volume 35, Issue 4, July 2025.
The molecular profile of adult primary leptomeningeal gliomatosis closely aligned with that of adult‐type glioblastoma, IDH‐wildtype, CNS WHO grade 4. Abstract Adult primary leptomeningeal gliomatosis (PLG) is a rare, rapidly progressive and fatal disease characterized by prominent leptomeningeal infiltration by a glial tumor without an identifiable ...
Yi Zhu   +14 more
wiley   +1 more source

Morphometric parameters of the human pineal gland in relation to age, body weight and height [PDF]

open access: yes, 2002
The aim of the study was to compare the size, weight, volume and density of the pineal gland in several groups divided by age, body weight and height. 80 human pineal glands were included in the study.
Golan, Janusz   +4 more
core   +1 more source

Randomized trial of polychromatic blue-enriched light for circadian phase shifting, melatonin suppression, and alerting responses. [PDF]

open access: yes, 2019
Wavelength comparisons have indicated that circadian phase-shifting and enhancement of subjective and EEG-correlates of alertness have a higher sensitivity to short wavelength visible light.
Ayers, M.   +12 more
core   +2 more sources

MicroRNAs in the Pineal Gland

open access: yesJournal of Biological Chemistry, 2012
Background: MicroRNAs have not been studied in the pineal gland, the source of circulating melatonin. Results: The pineal miRNA population is profiled; developmental and tissue-specific patterns are described.
Samuel J. H. Clokie   +4 more
semanticscholar   +1 more source

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 14, Page 3178-3210, July 2025.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison   +15 more
wiley   +1 more source

Expression of three GnRH receptors in specific tissues in male and female sea lampreys Petromyzon marinus at three distinct life stages [PDF]

open access: yes, 2013
Two recently cloned gonadotropin-releasing hormone (GnRH) receptors (lamprey GnRH-R-2 and lamprey GnRH-R-3) along with lamprey (l) GnRH-R-1 were shown to share similar structural features and amino acid motifs common to other vertebrate receptors.
Daukss, Dana M.   +3 more
core   +1 more source

Morphology of the Human Pineal Gland in Relation to Age and Sex [PDF]

open access: yes, 2003
Plasma concentration of melatonin - the hormone secreted by the human pineal gland is highest in children between 1 and 3 years of age. In the next age groups its levels decrease and in adults they are by approximately 80% lower.
Dokov, V., Dokov, W.
core   +2 more sources

Melatonin: A Potential Therapy for Osteoporosis With Insights Into Molecular Mechanisms

open access: yesJournal of Pineal Research, Volume 77, Issue 4, July 2025.
ABSTRACT Melatonin is a versatile neurohormone with diverse molecular functions, including sleep regulation, inflammation reduction, antioxidant activity, immune modulation, and anticancer properties. In bone metabolism, it promotes osteoblast formation, inhibits osteoclast activity, and synchronizes skeletal tissue rhythms to support bone health.
Ko‐Hsiu Lu   +4 more
wiley   +1 more source

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