Results 41 to 50 of about 1,300,579 (271)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

A New Key Delivery Method in Wireless Network

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2017
The development of networking technologies and the increase of digital devices have made multimedia transmission quick and easy. However, digital data transmission over open communication channels has introduced a number of security implications, such as
Çağatay Ay
doaj  

Delayed radial head dislocation after radial shaft fracture fixation: a case report and review of the literature

BMC Surgery, 2022
Background Ipsilateral fracture of the radial shaft with dislocation of the radial head was a rare injury, but a delayed radial head dislocation after radial shaft fracture fixation was more extremely rare.
Jiyong Yang, Jie Zhang, Zhengzhong Yang
doaj   +1 more source

Performance Analysis of a Cache-Aided Wireless Heterogeneous Network With Secrecy Constraints

IEEE Access, 2021
In this paper, we analyze the impact of caching on the performance of a cache enabled system with heterogeneous traffic where one of the users need to be served with confidential data.
Georgios Smpokos, Zheng Chen, Parthajit Mohapatra, Nikolaos Pappas   +3 more
doaj   +1 more source

'I play, therefore I learn?' Measuring the Evolution of Perceived Learning and Game Experience in the Design Flow of a Serious Game [PDF]

, 2010
This article explores how the serious game Poverty Is Not a Game (PING) is experienced by high school students in its subsequent design stages. We first focus on the multifaceted construct of game experience and how it is related to serious games.
Courtois, Cédric, De Grove, Frederik, De Marez, Lieven, Van Looy, Jan   +3 more
core   +1 more source

Eavesdropping on the "ping-pong" quantum communication protocol

, 2002
The proposed eavesdropping scheme reveals that the quantum communication protocol recently presented by Bostrom and Felbinger [Phys. Rev. Lett.
Antoni Wójcik, C. Kurtsiefer, C. H. Bennett   +2 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Ping-Ping

, 1927
Relata la historia de una pequeña niña que fue comprada por un marinero quién le enseñó la doctrina cristiana, la bautizó y de ella nació el anhelo de ser monja en agradecimiento por aceptar su humilde ofrenda como promesa.
openaire   +2 more sources

Container Relocation and Retrieval Tradeoffs Minimizing Schedule Deviations and Relocations

IEEE Open Journal of Intelligent Transportation Systems
Ports are striving to improve operational efficiency in the context of constantly growing volumes of trade. In this context, port terminal storage yard operation is key, since complexity and poor coordination lead to containers stacked without ...
Robert Klar, Anders Andersson, Anna Fredriksson, Vangelis Angelakis   +3 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source