Results 61 to 70 of about 2,039,140 (369)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Faster Convergence With Less Communication: Broadcast-Based Subgraph Sampling for Decentralized Learning Over Wireless Networks

IEEE Open Journal of the Communications Society
Decentralized stochastic gradient descent (D-SGD) is a widely adopted optimization algorithm for decentralized training of machine learning models across networked agents.
Daniel Perez Herrera, Zheng Chen, Erik G. Larsson   +2 more
doaj   +1 more source

'I play, therefore I learn?' Measuring the Evolution of Perceived Learning and Game Experience in the Design Flow of a Serious Game [PDF]

, 2010
This article explores how the serious game Poverty Is Not a Game (PING) is experienced by high school students in its subsequent design stages. We first focus on the multifaceted construct of game experience and how it is related to serious games.
Courtois, Cédric, De Grove, Frederik, De Marez, Lieven, Van Looy, Jan   +3 more
core   +1 more source

Ping-Pong—Tumor and Host in Pancreatic Cancer Progression

Frontiers in Oncology, 2019
Metastasis is the main cause of high pancreatic cancer (PaCa) mortality and trials dampening PaCa mortality rates are not satisfying. Tumor progression is driven by the crosstalk between tumor cells, predominantly cancer-initiating cells (CIC), and ...
W. Mu, Zhe Wang, M. Zöller
semanticscholar   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Kablosuz Ağlarda Yeni Bir Anahtar Dağıtım Yöntemi

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2017
Ağ teknolojilerinin gelişimi ve dijital cihazların artışı multimedya iletimini hızlı ve kolay kılmıştır. Bununla birlikte açık haberleşme kanalları üzerinden yapılan dijital veri iletimi, telif hakkı ihlalleri, dolandırıcılık vb.
Çağatay Ay
doaj  

Container Relocation and Retrieval Tradeoffs Minimizing Schedule Deviations and Relocations

IEEE Open Journal of Intelligent Transportation Systems
Ports are striving to improve operational efficiency in the context of constantly growing volumes of trade. In this context, port terminal storage yard operation is key, since complexity and poor coordination lead to containers stacked without ...
Robert Klar, Anders Andersson, Anna Fredriksson, Vangelis Angelakis   +3 more
doaj   +1 more source

Serious Games and the Pleasure of Learning: The Whys and How of a Serious Game about Poverty and Social Exclusion [PDF]

, 2010
This paper describes and explains the decisions that have been made in the conceptualization and development of the serious game Poverty Is Not a Game (PING).
De Grove, Frederik, Van Looy, Jan, Wouters, Wim   +2 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Polish shop(ping) as Translanguaging Space

, 2017
This article investigates how spatial layout, the display of goods, body movement and gaze work alongside verbalised linguistic codes in creating a Translanguaging Space, using data from a linguistic ethnography project in a family retail shop in East ...
Zhu Hua, Li Wei, Agnieszka Lyons
semanticscholar   +1 more source