Results 71 to 80 of about 3,933 (191)

Polycystic ovary syndrome: a dermatologic approach [PDF]

, 2011
Polycystic ovary syndrome (POS) is one of the most common endocrine abnormalities affecting women of reproductive age. It is a cause of significant social embarrassment and emotional distress.
Bagatin, Edileia, Costa, Dailana Louvain Marinho, Manela-azulay, Mônica, Moura, Heloisa Helena Gonçalves De, Sodré, Celso Tavares   +4 more
core   +3 more sources

New Twists in the Chemistry of Thioureas: 1,3‐Thiazolidines as a Vector of Sustainability

Chemistry – A European Journal, Volume 30, Issue 57, October 11, 2024.
A new sustainable method for synthesizing 1,3‐N,S‐heterocycles, including 1,3‐thiazolidine‐2‐imines and 4,5‐dihydrothiazol‐2‐amines is reported. This innovative approach offers considerable shorter reaction times with higher yields, reduced energy consumption, and the elimination of hazardous chemicals.
Guillermo Canudo‐Barreras, Raquel P. Herrera, M. Concepción Gimeno   +2 more
wiley   +1 more source

New Pharmacological Agents to Aid Smoking Cessation and Tobacco Harm Reduction: What has been Investigated and What is in the Pipeline? [PDF]

, 2016
A wide range of support is available to help smokers to quit and aid attempts at harm reduction, including three first-line smoking cessation medications: nicotine replacement therapy, varenicline and bupropion.
A Bisaga, A Jackson, A Kukkar, A Lenox-Smith, A Mann, A Parsons, A Sood, A Sood, A Verrotti, AE Evins, AH Glassman, AK Shinn, AM Joseph, AR Buchhalter, AS Rauhut, AV Prochazka, B Gaster, B Pasternak, B Spring, B Westenberger, BA Johnson, BF Grant, BM Kuehn, C Bullen, C Lerman, C Reavill, C Zona, C-Y Yeh, CA Martin, CD Cropp, CE Gartner, CF Koegelenberg, CL Bennett, CL DeVane, CL Strasinger, CT Bolliger, D Gonzales, D Hammond, D Kotz, D Kotz, D Kotz, D Mischoulon, D Moore, DA Baker, DA Baltieri, DA Revicki, Damian M. Cummings, DE Hilleman, DJ Romberger, DK Hatsukami, DK Hatsukami, DK Miller, DP Tashkin, E Beard, E Beard, E Beard, E Gere-Pászti, E Nowakowska, EA Finkelstein, EA Gilpin, EA McClure, EA Zimovetz, EC Westman, ED Levin, EG Guy, EH Cerny, EJ Jensen, EJ Mills, EJ Mills, EJ Wagena, Emma Beard, EW Tuan, F Wang, FT Filippidis, G Addolorato, G Chiara Di, G Cucchiaro, G Sutherland, GA Higgins, GM Keating, H Kitagawa, H McRobbie, H McRobbie, H Minami, H Myrick, H Pine-Abata, H-J Aubin, HM Schuller, I Berlin, J Balmford, J Brown, J Cornuz, J Foulds, J Foulds, J Kaper, J Kay, J Leaviss, J Ollivier, J Rose, J Shearer, J Shearer, J Yang, J-F Etter, J-G Gehricke, JA Dani, JE Henningfield, JE Henningfield, JE Rose, JE Rose, JE Sarginson, JF Rosenbaum, JM Ramon, JM Samet, JN Liberman, JO Ebbert, JO Ebbert, JR DiFranza, JR Hughes, JR Hughes, JS Ballon, JS Brown, JS Fowler, JW Lockner, K Bolin, K Demyttenaere, K Hara, K Ogita, K Silla, KA Holes-Lewis, KA Kasza, KA Perkins, KA Sacco, KC Waterman, KE Dunn, KE Farsalinos, KH Thomas, KP Garnock-Jones, KS Paudel, L Annemans, L Kozlowski, L Leggio, L Lima De, L Schmaal, L Shahab, L Shahab, LF Gaal Van, LH Ferry, Lion Shahab, LS Brose, LS Brose, LS Covey, M Farrell, M Harrison-Woolrych, M Hoogendoorn, M Khalifa, M Lader, M Mahmoudi, M McCarty, M Mugnaini, M Mula, M Neovius, M Ng, M Pravetoni, M Pravetoni, M Raw, M Raw, M Sofuoglu, M Sofuoglu, M Sofuoglu, M Sofuoglu, M Williams, M Wimbiscus, MA Jacobs, MA Russell, MA Russell, MC Fiore, ME Hadwiger, ME Jarvik, ME Jarvik, ME Mooney, ME Page, ME Thase, MFG Murphy, MG LeSage, MG LeSage, MH Ebell, MH Rapaport, ML Goniewicz, MM Moran, MY Bertram, N Benowitz, N Lindblom, N Walker, N Woolacott, NB Edwards, NF Woolacott, NL Benowitz, P Aveyard, P Farid, P Franks, P Gerrard, P Hajek, P Hajek, P Hajek, P Hajek, P Jha, P Maurer, P Popik, PH Hoogsteder, PH Silverstone, PM Bet, PM Cinciripini, PS Masand, R Benyamin, R Freedman, R Niaura, R Niaura, R Ray, R Richmond, R Shytle, R Taylor, R West, R West, R West, R West, R West, R West, R West, RA Brown, RA Schnoll, RA Schnoll, RB Barlow, RC Smith, RD Hurt, RD Hurt, RE Fahim, RF Yoshimura, RM Anthenelli, RM Pinder, Robert West, S Brimijoin, S Denford, S Greenland, S Leonard, S Shiffman, S Shiffman, S Shiffman, S Shiffman, S Singh, S Thornley, S Tonstad, S Tonstad, S Wanwimolruk, SA Ornish, SC Licata, SD Hall, SD Satoskar, SE Adkison, SH Villiers de, SL McElroy, SM Boekholdt, SM Holliday, SP Lakshmi, SS Hecht, Susan Michie, T Blondal, T Green, T Paparrigopoulos, T Raupach, TB Johnstone, TE Langley, TE Meyer, TJ Meine, TL Awtry, TM Luger, TR Franklin, U Eckstein-Ludwig, U Perngparn, V Butterweck, V Gligorijevic, V Klimek, V Varga, V Vengeliene, VS Kumar, W Berrettini, W Hao, W Pichayakorn, W Qiumei, WI Najm, WR Hiatt, X Shen, Y Buggy, Y Khazaal, Y-S Kim   +293 more
core   +1 more source

Pioglitazone hydrochloride: chemopreventive potential and development of site-specific drug delivery systems

Drug Delivery, 2014
The aim of this study was to investigate the potential of pioglitazone hydrochloride as a promising anticancer agent and then to design and evaluate the colon-targeted delivery system. The role of pioglitazone hydrochloride as a promising anticancer agent was evaluated by in vitro cell line studies and in vivo 1,2-dimethylhydrazine-induced colon ...
Vivek Ranjan, Sinha, Shilpa, Sethi
openaire   +2 more sources

Identification and characterisation of functional Kir6.1‐containing ATP‐sensitive potassium channels in the cardiac ventricular sarcolemmal membrane

British Journal of Pharmacology, Volume 181, Issue 18, Page 3380-3400, September 2024.
Abstract Background and Purpose The canonical Kir6.2/SUR2A ventricular KATP channel is highly ATP‐sensitive and remains closed under normal physiological conditions. These channels activate only when prolonged metabolic compromise causes significant ATP depletion and then shortens the action potential to reduce contractile activity.
Sean Brennan, Shen Chen, Samir Makwana, Simona Esposito, Lauren R. McGuinness, Abrar I. M. Alnaimi, Mark W. Sims, Manish Patel, Qadeer Aziz, Leona Ojake, James A. Roberts, Parveen Sharma, David Lodwick, Andrew Tinker, Richard Barrett‐Jolley, Caroline Dart, Richard D. Rainbow   +16 more
wiley   +1 more source

Effects of Pioglitazone Hydrochloride on Japanese Patients with Type 2 Diabetes Mellitus

Journal of Atherosclerosis and Thrombosis, 2007
The effects of pioglitazone hydrochloride monotherapy on abnormal lipid control were evaluated in Japanese patients with type 2 diabetes mellitus, comparing with glibenclamide monotherapy.Patients were randomly assigned to receive, once daily, pioglitazone hydrochloride, at 15 mg or 30 mg (n=46), or glibenclamide, at 1.25 mg or 2.5 mg (n=46).
Tamio, Teramoto, Nobuhiro, Yamada, Kohji, Shirai, Yasushi, Saito   +3 more
openaire   +3 more sources

Evaluation of the protective effect of Curcuma longa and PPARγ agonist, pioglitazone on paraquat‐induced lung injury in rats

Immunity, Inflammation and Disease, Volume 12, Issue 8, August 2024.
The effect of Curcuma longa (Cl) on inhaled paraquat (PQ)‐induced lung injury was examined. CI and pioglitazone ameliorated lung injury induced by inhaled PQ. CI improved lung inflammation similar to dexamethasone. Synergic effect of pioglitazone and CI was shown.
Mohammad Hossein Eshaghi Ghalibaf, Mohammad Ehsan Taghavi zadeh Yazdi, Mona Mansourian, Nema Mohammadian Roshan, Mohammad Hossein Boskabady   +4 more
wiley   +1 more source

Recent Advances in Nanomedicine for Ocular Fundus Neovascularization Disease Management

Advanced Healthcare Materials, Volume 13, Issue 17, July 5, 2024.
Ocular fundus neovascularization diseases are prominent etiologies of visual impairment. Specifically, nanomedicine arose at an opportune time, which has paved the way to fulfill the effective ocular fundus drug delivery and achieve precise drug release control capacity, thus further improving the therapeutic effect.
Yifan Zhou, Mingyu Xu, Wenyue Shen, Yufeng Xu, An Shao, Peifang Xu, Ke Yao, Haijie Han, Juan Ye   +8 more
wiley   +1 more source

Continuous cerebroventricular administration of dopamine: A new treatment for severe dyskinesia in Parkinson’s disease? [PDF]

, 2017
In Parkinson’s disease (PD) depletion of dopamine in the nigro-striatal pathway is a main pathological hallmark that requires continuous and focal restoration. Current predominant treatment with intermittent oral administration of its precursor, Levodopa
A. Jonneaux, Agil, B. Do Van, Bordet, C. Lachaud, C. Laloux, C. Moreau, Carta, Cenci, Chaudhuri, Chen, Ciesielska, D. Devos, Datla, De Lau, De Yebenes, Devos, Drapier, Espadas, F. Gouel, Fahn, Fornai, Francardo, G. Garcon, Gershanik, Hargraves, Hastings, Horne, J.A. Duce, J.C. Devedjian, Jeon, Jia, K. Timmerman, Kroin, Laloux, M. Petrault, N. Rouaix, Nair, Olanow, Olsson, Paladini, R. Bordet, Schallert, Venna   +43 more
core   +3 more sources

The 'top 100' drugs and classes in England An updated 'starter formulary' for trainee prescribers. [PDF]

, 2018
AIMS: Prescribing is a complex skill required of doctors and, increasingly, other healthcare professionals. Use of a personal formulary can help to develop this skill. In 2006-9, we developed a core list of the 100 most commonly prescribed drugs. Our aim
Audi, S, Baker, EH, Burrage, DR, Coleman, JJ, Hitchings, AW, Lonsdale, DO, Pontefract, S   +6 more
core   +2 more sources