Results 61 to 70 of about 3,933 (191)
Journal of Diabetes, Volume 17, Issue 4, April 2025.ABSTRACT Background Diabetes is a prevalent public health issue worldwide, and the cognitive dysfunction and subsequent dementia caused by it seriously affect the quality of life of patients. Methods Recent studies were reviewed to provide a comprehensive summary of the risk factors, pathogenesis, pathological changes and potential drug treatments for ...
Xiaoyu Meng +14 more
wiley +1 more source
Photothermal‐Responsive Soluble Microneedle Patches for Meibomian Gland Dysfunction Therapy
Advanced Science, Volume 12, Issue 11, March 20, 2025.This study provides a soluble microneedles (MN) patch that facilitates the transdermal release of rosiglitazone in response to near‐infrared ray induced temperature changes. The MN shows therapeutic efficiency for meibomian gland dysfunction (MGD) in high‐fat mice.
Fei Yu +15 more
wiley +1 more source
分子生物学的手法によるPPAR活性化薬の性状解析 [PDF]
, 2018 筑波大学 (University of Tsukuba ...
Sakamoto Junichi, 坂本 潤一
core +1 more source
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 11, Issue 1, January-March 2025.Abstract Recent clinical trials on slowing dementia progression have led to renewed focus on finding safer, more effective treatments. One approach to identify plausible candidates is to assess whether existing medications for other conditions may affect dementia risk. We conducted a systematic review to identify studies adopting a data‐driven approach
Benjamin R. Underwood +15 more
wiley +1 more source
SAR Studies on the Inhibitors for the Treatment of Inflammatory Diseases [PDF]
, 2016 School of Molecular Sciences(Chemistry)Inflammation is defensive host response that occurs from infection and injury and the inflammatory process is the pivotal physiological response of our body and essential part of the human physiology.
Kim, Min-Jeong
core
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 7, Issue 12, Page 1207-1227, December 2024.Abstract Cognitive impairment affects around 19% of community‐dwelling older adults in the United States. Pharmacists can play a significant role in identifying and deprescribing cognitive‐impairing medications through cognitive‐focused medication reviews or as part of comprehensive medication management.
Jacob Stanton +4 more
wiley +1 more source
Pharmacokinetic interactions of pioglitazone [PDF]
, 2007 Pioglitazone is a thiazolidinedione compound used in the treatment of type 2 diabetes. It has been reported to be metabolised by multiple cytochrome P450 (CYP) enzymes, including CYP2C8, CYP2C9 and CYP3A4 in vitro.
Jaakkola, Tiina
core
Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction [PDF]
, 2010 PURPOSE: AMPK plays a crucial role in the regulation of the energy metabolism of the heart. During ischaemia, AMPK activation is a known adaptative prosurvival mechanism that helps to maintain the energy levels of the myocardium.
Davidson, SM +5 more
core +2 more sources
Journal of the Peripheral Nervous System, Volume 29, Issue 4, Page 406-414, December 2024.Abstract Aim Obesity is a major risk factor for diabetic peripheral neuropathy (DPN) in type 2 diabetes (T2D). This study investigated the effect of glucose lowering medication associated with weight change on DPN. Methods Participants with T2D were grouped based on whether their glucose lowering medications were associated with weight gain (WG) or ...
Georgios Ponirakis +27 more
wiley +1 more source
Cutaneous side effects of diabetes treatment [PDF]
, 2016 As lesões cutâneas são frequentes na diabetes mellitus, havendo um envolvimento da pele em cerca de 30 a 91% dos doentes durante o curso da doença. Estas podem ser não infeciosas ou autoimunes, infeciosas ou resultar de complicações do tratamento da ...
Borges-Costa, J, Gomes, F
core