Formulation and in vitro evaluation of mucoadhesive microspheres of pioglitazone hydrochloride
The work was aim to formulate and evaluate mucoadhesive microspheres of Pioglitazone Hydrochloride for treatment of diabetes type-2 by combining the pote ntial advantages of mucoadhesion with controlled dr ug delivery using various ratio of polymers.
Wattamwar Mayur M +3 more
openaire +1 more source
Background: The primary aim of this research was to address the significant challenge of low and unpredictable drug absorption following oral administration, which often occurs due to poor water solubility.
Shweta Kyadalwar +4 more
doaj +1 more source
Effect of Additives on the Physicochemical and Drug Release Properties of Pioglitazone Hydrochloride Spherical Agglomerates [PDF]
Purpose: To prepare and evaluate spherical agglomerates of pioglitazone hydrochloride (PGH) for direct compression with different additives.Method: Spherical agglomerates of pioglitazone hydrochloride were prepared by emulsion solvent diffusion method ...
Kumar, S, Patil, S, Pawar, A
core +2 more sources
Antiangiogenic effect of gemcitabine following metronomic administration in a pancreas cancer model [PDF]
Gemcitabine shows a marked antitumor effect as a result of its cytotoxic action toward proliferative cells. In this article, we aim to investigate the potential antitumor and antiangiogenic effect of gemcitabine following a metronomic schedule that ...
Capellá, G. (Gabriel) +9 more
core +1 more source
Effects of vitamin D3 derivate calcitriol on pharmacological reactivity of aortic rings in a rodent PCOS model [PDF]
BACKGROUND: The aim of this study was to examine the effects of the hyperandrogenic state in dihydrotestosterone (DHT)-induced polycystic ovary syndrome (PCOS), the vascular responses to different vasoactive agents, and the modulatory role of vitamin D3.
Benkő, Rita +13 more
core
Pioglitazone Hydrochloride Extends the Lifespan of Caenorhabditis elegans by Activating DAF-16/FOXO- and SKN-1/NRF2-Related Signaling Pathways. [PDF]
Jia W +6 more
europepmc +1 more source
Effects of Hydro-alcoholic Extract from Arctium lappa L. (Burdock) Root on Gonadotropins, Testosterone, and Sperm Count and Viability in Male Mice with Nicotinamide/ Streptozotocin-Induced Type 2 Diabetes [PDF]
Background: Reproductive dysfunction is a complication of diabetes. Arctium lappa (burdock) root has hypoglycemic and antioxidative properties, which are traditionally used for treatment of impotence and sterility.
Ahangarpour, Akram +4 more
core
Effects of vitamin D3 derivative--calcitriol on pharmacological reactivity of aortic rings in a rodent PCOS model. [PDF]
BACKGROUND: The aim of this study was to examine the effects of the hyperandrogenic state in dihydrotestosterone (DHT)-induced polycystic ovary syndrome (PCOS), the vascular responses to different vasoactive agents, and the modulatory role of vitamin ...
Benko, Rita +13 more
core
Background This study presents the development and validation of a UV spectrophotometric method for the simultaneous estimation of teneligliptin hydrobromide hydrate (TEN) and pioglitazone hydrochloride (PIO) in pharmaceutical dosage forms.
Ravi Shankar Gupta +6 more
doaj +1 more source
UEG Week 2025 Poster Presentations
United European Gastroenterology Journal, Volume 13, Issue S8, Page S803-S1476, October 2025.
wiley +1 more source

