Results 131 to 140 of about 58,639 (259)
Aquaporins (AQPs) are tetrameric channel proteins regulating the transmembrane flux of small uncharged solutes and in particular water in living organisms.
M. Bienert +4 more
semanticscholar +1 more source
ABSTRACT Head rice yield (HRY) is a crucial quality trait that determines the final commodity yield and commercial value of rice. Conversely, chalkiness represents an undesirable appearance characteristic, significantly impairing rice marketability. Thus, developing rice germplasms with superior HRY and appearance traits is highly desirable for rice ...
Tengwei Yu +6 more
wiley +1 more source
μ-calpain binds to lipid bilayers via the exposed hydrophobic surface of its Ca2+-activated conformation [PDF]
μ- and m-calpain are cysteine proteases requiring micro- and millimolar Ca2+ concentrations for their activation in vitro. Among other mechanisms, interaction of calpains with membrane phospholipids has been proposed to facilitate their activation by ...
Assfalg-Machleidt, Irmgard +5 more
core +1 more source
Direct PIP2 binding mediates stable oligomer formation of the serotonin transporter
The human serotonin transporter (hSERT) mediates uptake of serotonin from the synaptic cleft and thereby terminates serotonergic signalling. We have previously found by single-molecule microscopy that SERT forms stable higher-order oligomers of differing
Andreas Anderluh +6 more
semanticscholar +1 more source
A Single‐Base Mutation in TaWAK3‐B Reduces Plant Height via Cytoskeleton in Bread Wheat
ABSTRACT Introduction of Reduced height (Rht) genes into modern wheat cultivars has resulted in ‘Green Revolution’ that skyrocketed wheat grain yields worldwide since the 1960s. These ‘Green Revolution’ cultivars show shorter plant height, but higher lodging resistance and harvest index.
Naijiao Wang +16 more
wiley +1 more source
Ezrin activation by LOK phosphorylation involves a PIP2-dependent wedge mechanism
How cells specify morphologically distinct plasma membrane domains is poorly understood. Prior work has shown that restriction of microvilli to the apical aspect of epithelial cells requires the localized activation of the membrane-F-actin linking ...
T. Pelaseyed +5 more
semanticscholar +1 more source
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley +1 more source
How cholesterol regulates endothelial biomechanics
As endothelial cells form the barrier between blood flow and surrounding tissue, many of their functions depend on mechanical integrity, in particular that of the plasma membrane.
Zhongkui eHong +6 more
doaj +1 more source
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley +1 more source
Studies on PIP2-bisphosphomonoesterase activity in human platelets.
An occurrence of phosphatidylinositol 4,5-bisphosphate (PIP2) phosphomonoesterase in human platelets was demonstrated by analyzing phosphoinositides metabolism. The activity of the enzyme was maximum at pH 7.0. It was active even in the absence of Ca2+ or Mg2+ but it was enhanced in the presence of Mg2+ or NaF.
Y, Uemura +4 more
openaire +3 more sources

