Results 11 to 20 of about 3,380 (162)
Actinomycin Derivatives: Structural Diversification and Biological Activities. [PDF]
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Can Ö, Bedir E.
europepmc +2 more sources
Microbial‐derived Exerkines preserve muscle size and function during disuse in aged mice in a sex‐dependent manner [PDF]
Abstract Disuse‐induced muscle atrophy is a critical clinical challenge in older adults. Existing countermeasures have largely failed to preserve muscle size and function, underscoring the need for novel therapeutic strategies. We recently identified pipecolic acid and succinate (PAS) as microbial‐derived exerkines that prevent disuse‐induced atrophy ...
Daredia J +5 more
europepmc +2 more sources
Metabolism of Pipecolic Acid in a Pseudomonas Species V. Pipecolate Oxidase and Dehydrogenase [PDF]
Oxidation of pipecolate to Δ 1 -piperideine-6-carboxylate is catalyzed by pipecolate oxidase, an inducible, membrane-bound dehydrogenase associated with the electron transport components of Pseudomonas putida P2.
M L, Baginsky, V W, Rodwell
openaire +2 more sources
Integrative Metabolic Signatures for Hepatic Radiation Injury. [PDF]
Radiation-induced liver disease (RILD) is a dose-limiting factor in curative radiation therapy (RT) for liver cancers, making early detection of radiation-associated liver injury absolutely essential for medical intervention.
Irwin Jack Kurland +8 more
doaj +1 more source
Concise and Straightforward Asymmetric Synthesis of a Cyclic Natural Hydroxy-Amino Acid
An enantioselective total synthesis of the natural amino acid (2S,4R,5R)-4,5-di-hydroxy-pipecolic acid starting from D-glucoheptono-1, 4-lactone is presented.
Mario J. Simirgiotis +3 more
doaj +1 more source
Plant non-specific lipid transfer proteins (nsLTPs) are small proteins capable of transferring phospholipids between membranes and binding non-specifically fatty acids in vitro.
Carol Bvindi +6 more
doaj +1 more source
The study was targeted at naturally colored cotton: white, white with a shade of ash gray, white with a creamy shade, and brown with a shade of marmoreal pink, collected from eighteen lines and cultivars.
Sergei Vladimirovich Grigorev +3 more
doaj +1 more source
N-hydroxypipecolic acid primes plants for enhanced microbial pattern-induced responses
The bacterial elicitor flagellin induces a battery of immune responses in plants. However, the rates and intensities by which metabolically-related defenses develop upon flagellin-sensing are comparatively moderate.
Marie Löwe +9 more
doaj +1 more source
Broadening of the genetic diversity of donors of resistance to biotic environmental factors is a challenging problem concerning Triticum L., which can be solved by using wild relatives of wheat, in particular, Aegilops tauschii Coss., in breeding ...
T. V. Shelenga +8 more
doaj +1 more source
Verticillium transcription activator of adhesion 3 (Vta3) is required for plant root colonization and pathogenicity of the soil-borne vascular fungus Verticillium dahliae.
Isabel Maurus +15 more
doaj +1 more source

