Results 11 to 20 of about 3,380 (162)

Actinomycin Derivatives: Structural Diversification and Biological Activities. [PDF]

open access: yesChemMedChem
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Can Ö, Bedir E.
europepmc   +2 more sources

Microbial‐derived Exerkines preserve muscle size and function during disuse in aged mice in a sex‐dependent manner [PDF]

open access: yesPhysiol Rep
Abstract Disuse‐induced muscle atrophy is a critical clinical challenge in older adults. Existing countermeasures have largely failed to preserve muscle size and function, underscoring the need for novel therapeutic strategies. We recently identified pipecolic acid and succinate (PAS) as microbial‐derived exerkines that prevent disuse‐induced atrophy ...
Daredia J   +5 more
europepmc   +2 more sources

Metabolism of Pipecolic Acid in a Pseudomonas Species V. Pipecolate Oxidase and Dehydrogenase [PDF]

open access: yesJournal of Bacteriology, 1967
Oxidation of pipecolate to Δ 1 -piperideine-6-carboxylate is catalyzed by pipecolate oxidase, an inducible, membrane-bound dehydrogenase associated with the electron transport components of Pseudomonas putida P2.
M L, Baginsky, V W, Rodwell
openaire   +2 more sources

Integrative Metabolic Signatures for Hepatic Radiation Injury. [PDF]

open access: yesPLoS ONE, 2015
Radiation-induced liver disease (RILD) is a dose-limiting factor in curative radiation therapy (RT) for liver cancers, making early detection of radiation-associated liver injury absolutely essential for medical intervention.
Irwin Jack Kurland   +8 more
doaj   +1 more source

Concise and Straightforward Asymmetric Synthesis of a Cyclic Natural Hydroxy-Amino Acid

open access: yesMolecules, 2014
An enantioselective total synthesis of the natural amino acid (2S,4R,5R)-4,5-di-hydroxy-pipecolic acid starting from D-glucoheptono-1, 4-lactone is presented.
Mario J. Simirgiotis   +3 more
doaj   +1 more source

Potato Non-Specific Lipid Transfer Protein StnsLTPI.33 Is Associated with the Production of Reactive Oxygen Species, Plant Growth, and Susceptibility to Alternaria solani

open access: yesPlants, 2023
Plant non-specific lipid transfer proteins (nsLTPs) are small proteins capable of transferring phospholipids between membranes and binding non-specifically fatty acids in vitro.
Carol Bvindi   +6 more
doaj   +1 more source

Differences in Metabolites of White and Naturally Colored Cotton: Implications for Biofunctional and Aseptic Textiles

open access: yesJournal of Natural Fibers, 2022
The study was targeted at naturally colored cotton: white, white with a shade of ash gray, white with a creamy shade, and brown with a shade of marmoreal pink, collected from eighteen lines and cultivars.
Sergei Vladimirovich Grigorev   +3 more
doaj   +1 more source

N-hydroxypipecolic acid primes plants for enhanced microbial pattern-induced responses

open access: yesFrontiers in Plant Science, 2023
The bacterial elicitor flagellin induces a battery of immune responses in plants. However, the rates and intensities by which metabolically-related defenses develop upon flagellin-sensing are comparatively moderate.
Marie Löwe   +9 more
doaj   +1 more source

Metabolomic approach to search for fungal resistant forms of Aegilops tauschii Coss. from the VIR collection

open access: yesВавиловский журнал генетики и селекции, 2020
Broadening of the genetic diversity of donors of resistance to biotic environmental factors is a challenging problem concerning Triticum L., which can be solved by using wild relatives of wheat, in particular, Aegilops tauschii Coss., in breeding ...
T. V. Shelenga   +8 more
doaj   +1 more source

Verticillium dahliae Vta3 promotes ELV1 virulence factor gene expression in xylem sap, but tames Mtf1-mediated late stages of fungus-plant interactions and microsclerotia formation.

open access: yesPLoS Pathogens, 2023
Verticillium transcription activator of adhesion 3 (Vta3) is required for plant root colonization and pathogenicity of the soil-borne vascular fungus Verticillium dahliae.
Isabel Maurus   +15 more
doaj   +1 more source

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