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Piper nigrum and Piperine: An Update

Phytotherapy Research, 2013
Black pepper (Piper nigrum L.) is a very widely used spice, known for its pungent constituent piperine. However, in addition to its culinary uses, pepper has important medicinal and preservative properties, and, more recently, piperine has been shown to have fundamental effects on p‐glycoprotein and many enzyme systems, leading to biotransformative ...
Murlidhar, Meghwal, T K, Goswami
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The biosynthesis of piperine in Piper nigrum

Phytochemistry, 1990
Abstract A new acyltransferase from shoots of Piper nigrum was detected which catalyses the synthesis of piperine in the presence of piperoyl-coenzyme A and piperidine. Minor reaction rates were observed with pyrrolidine and 3-pyrroline, while various other related heterocyclic compounds were not accepted as substrates.
Jutta G. Geisler, Georg G. Gross
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Piper Nigrum L.

Piper nigrum L., commonly known as black pepper, is a species of tropical plant and belongs to the family Piperaceae. Black pepper is a very common spice around the world and is often used to add flavor to dishes. The active ingredients found in black pepper have antioxidant and anti-inflammatory properties.
Azadeh Zarei, Mehrdad Karimi
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The bioactive amide alkaloids from the stems of Piper nigrum

Food Chemistry, 2023
Piper nigrum is an important aromatic plant, and its fruits (black and white pepper) are commonly used as food additives and spices. However, its stems were disposed as wastes. This research comprehensively investigated bioactive alkaloids of the stems, eight new dimeric amide alkaloids and eight known compounds were obtained.
Jie, Xu   +7 more
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Phytochemical Studies of Piper nigrum L

2023
Plants such as chamomile, echinacea, garlic, ginger, gingko, and black pepper are recognised for their medicinal properties and regular nutritious food intake. The knowledge of secondary metabolites present in this species that would be useful for producing natural products and disease diagnostic drugs that cure various diseases must be studied and ...
Hirva Jiteshbhai Mehta   +3 more
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Antibacterial constituents from the berries of Piper nigrum

Phytomedicine, 2004
Piper nigrum finds an extensive application in antibacterial preparations belonging to Ayurvedic system of medicine. A bioguided extraction and fractionation of the petroleum ether extract of the berries of P. nigrum afforded 2E, 4E, 8Z-N-isobutyleicosatrienamide (1), pellitorine (2), trachyone (3), pergumidiene (4) and isopiperolein B (5 ...
S Venkat, Reddy   +6 more
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An amide from fruits of Piper nigrum

Phytochemistry, 1997
Abstract A new amide, N -isobutyl amide of octadeca- trans -2- cis -4-dienoic acid has been isolated from the dried and crushed fruits of Piper nigrum , along with the known alkaloid, piperine. Complete assignments of the protons and carbons of the new amide and piperine have been made based on 2D NMR studies. © 1997 Elsevier Science Ltd.
Bina S. Siddiqui   +4 more
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ACAT inhibition of alkamides identified in the fruits of Piper nigrum

Phytochemistry, 2007
In this study, via a bioactivity-guided fractionation of MeOH extracts of the fruits of Piper nigrum, alkamide (5) and five previously-identified alkamides were isolated. Their structures were elucidated via spectroscopic analysis ((1)H, (13)C NMR and ESI-MS), as follows: retrofractamide A (1), pipercide (2), piperchabamide D (3), pellitorin (4 ...
Mun-Chual, Rho   +7 more
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Physicochemical properties of black pepper (Piper nigrum) starch

Carbohydrate Polymers, 2018
Black pepper (Piper nigrum) is among the most popular spices around the world. Starch is the major component of black pepper. However, little is known about functional properties of this starch. In this study, swelling, solubility, thermal properties, rheology, and enzyme susceptibility of 2 black pepper starches were studied and compared with those of
Fan, Zhu, Reuben, Mojel, Guantian, Li
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Phytochemical analysis of Piper nigrum

African Journal of Biological Sciences
Medicinal plants contain varieties of bioactive compounds such as alkaloids, terpenoids, tannins, flavonoids, steroids that possess anti-inflammatory, antioxidant, antibacterial, anti-diabetic functional properties and also protects from many chronic diseases.
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