Results 91 to 100 of about 73,428 (238)

Naphthalimide Trifluoroacetyl Acetonate: A Hydrazine-Selective Chemodosimetric Sensor [PDF]

, 2013
The trifluoroacetyl acetonate naphthalimide derivative 1 has been synthesized in good yield. In acetonitrile solution, compound 1 reacts selectively with hydrazine (NH2NH2) to give a five-membered ring.
Kim, Jong Seung, Lee, Min Hee, Sessler, Jonathan L., Yoon, Byungkwon   +3 more
core   +1 more source

Crystal structure of 2-(4-methylpiperazin-1-yl)quinoline-3-carbaldehyde

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C15H17N3O, the aldehyde group is twisted relative to the quinoline group by17.6 (2)° due to the presence of a bulky piperazinyl group in the ortho position.
R Nivedita Desai, S Sreenivasa, S. Naveen, N. K. Lokanath, P. A. Suchetan, D. B. Aruna Kumar   +5 more
doaj   +1 more source

The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. [PDF]

, 2010
Deregulation of the phosphoinositide-3-OH kinase (PI(3)K) pathway has been implicated in numerous pathologies including cancer, diabetes, thrombosis, rheumatoid arthritis and asthma.
Alex Berndt, Benjamin T Houseman, Christian Rommel, Daniel D Le, Fabrice Gorrec, Jeffrey P Shaw, Joseph I Pacold, Kevan M Shokat, Matthias K Schwarz, Olusegun Williams, Pascale Gaillard, Pingda Ren, Roger L Williams, Simon Miller, Thomas Rückle, Wai-Ching Hon, Yi Liu   +16 more
core   +2 more sources

Structural Investigation of bis(4-Methyl-1-piperazineglyoximato)dipyridinato Cobalt(III) Chloro Dinitrate Trihydrate

Molecules, 2005
The crystal and molecular structure of the title compound,C24H36CoN10O4·2(NO3)·3(H2O)·Cl, have been determined by X-ray analysis: Cc (No: 9),a = 17.6920(4) å, b = 11.8163(2) å, c = 16.4752(4) å, ß = 91.679(1)°, Z = 4.
H. Fun, S. Işık, M. Macit, M. Akkurt, S. Öztürk   +4 more
doaj   +1 more source

Antiplasmodial and Leishmanicidal Activities of 2-Cyano-3-(4-phenylpiperazine-1-carboxamido) Quinoxaline 1,4-Dioxide Derivatives

Molecules, 2012
Malaria and leishmaniasis are two of the World’s most important tropical parasitic diseases. Thirteen new 2-cyano-3-(4-phenylpiperazine-1-carboxamido) quinoxaline 1,4-dioxide derivatives (CPCQs) were synthesized and evaluated for their <em>in vitro&
Carlos Barea, Adriana Pabón, Silvia Galiano, Silvia Pérez-Silanes, German Gonzalez, Chloe Deyssard, Antonio Monge, Eric Deharo, Ignacio Aldana   +8 more
doaj   +1 more source

Crystal Structure of the Cysteine-Rich Domain of Mannose Receptor Complexed with a Sulfated Carbohydrate Ligand [PDF]

, 2000
The macrophage and epithelial cell mannose receptor (MR) binds carbohydrates on foreign and host molecules. Two portions of MR recognize carbohydrates: tandemly arranged C-type lectin domains facilitate carbohydrate-dependent macrophage uptake of ...
Bjorkman, Pamela J., Chirino, Arthur J., Feizi, Ten, Leteux, Christine, Liu, Yang, Misulovin, Ziva, Nussenzweig, Michel C.   +6 more
core   +2 more sources

A Cooperative Release of Mitochondrial DNA From Platelets and Neutrophils Drives an Interferon Signature in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

Trace ions rejection tunning in NF by selecting solution composition: Ion permeances estimation [PDF]

, 2017
Nanofiltration (NF) is suggested to selectively remove ionic species in aqueous process streams taking benefit of both membrane and aqueous solution composition. The importance of predicting and optimizing selective ion rejections by NF not only of major
Cortina Pallás, José Luís, Gibert Agulló, Oriol, Pagès Hernando, Neus, Reig i Amat, Mònica   +3 more
core   +2 more sources

Enantioselective Synthesis of Sulfinamidines via Asymmetric Rhodium–Catalyzed Imidation of Sulfenamides

ChemistryEurope, EarlyView.
In this work, a catalytic enantioselective imidation approach is presented for the preparation of enantioenriched sulfinamidines from sulfenamides, employing a chiral dirhodium(II) tetracarboxylate catalyst. This method enables the imidation of N,N‐bisalkyl sulfenamides in yields of up to 98% and enantiomeric ratios up to 98:2, with a catalyst loading ...
Michael Andresini, Théo Bissonnier, Juline Courtois, Pascal Retailleau, Benjamin Darses, Jean‐François Poisson, Tanguy Saget, Philippe Dauban   +7 more
wiley   +1 more source

1,4-Bis(2-nitrobenzyl)piperazine

IUCrData, 2019
The title compound, C18H20N4O4, was synthesized via the base-assisted reaction of piperazine and 2-nitrobenyl bromide in toluene: the complete molecule is generated by a crystallographic inversion centre in the solid state.
Hugh I. Crundwell, Rhiannon I. Grimmett, Guy Crundwell, Barry L. Westcott   +3 more
doaj   +1 more source