Results 201 to 210 of about 43,723 (349)

Design and evaluation of novel 1-(5-Isoquinolinesulfonyl) piperazine derivatives as potential Mycobacterium tuberculosis IMPDH Inhibitors: A comprehensive molecular modelling study

open access: gold
Thomas Aondofa Nyijime   +6 more
openalex   +1 more source

Glutamate Receptors and Synaptic Plasticity in Health and Disease: A Personal Journey

open access: yesHippocampus, Volume 36, Issue 1, January 2026.
ABSTRACT I describe my progress in understanding synaptic plasticity in the hippocampus. Over the decades my lab has focused on the roles of glutamate receptors (AMPARs, NMDARs, mGluRs and KARs) and associated signaling molecules in LTP and LTD. Most of our studies have been conducted in area CA1 (Schaffer collateral—commissural pathway) with some ...
Graham L. Collingridge
wiley   +1 more source

Spirocyclic Diamine Scaffolds for Medicinal Chemistry

open access: yesHelvetica Chimica Acta, Volume 109, Issue 1, January 2026.
Here we enumerated 391 spirocyclic diamine drug scaffolds with ring sizes four to eight and found that most of them are unknown. We prepared four novel such spirocycles and discovered a micromolar inhibitor of the M4 muscarinic receptor. ABSTRACT Medicinal chemistry requires the exploration of structurally diverse compound families to expand the ...
Aline Carrel   +3 more
wiley   +1 more source

Charge separation in the excited state electron donor—acceptor compounds containing the piperazine moiety

open access: green, 1991
Albert M. Brouwer   +6 more
openalex   +2 more sources

Stability of Synthetic Piperazines in Human Whole Blood.

open access: yesJournal of Analytical Toxicology, 2018
Timothy Lau   +2 more
semanticscholar   +1 more source

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