Results 111 to 120 of about 84,342 (322)

Synthesis and in vivo anti-ulcer evaluation of some novel piperidine linked dihydropyrimidinone derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Dihydropyrimidinone derivatives containing piperidine moiety were synthesised in a good yield. All the compounds were confirmed by elemental analysis and spectral data.
Mashooq Ahmad Bhat, Mohamed A. Al-Omar, Ahmed M. Naglah   +2 more
doaj   +1 more source

Deprotection Reagents in Fmoc Solid Phase Peptide Synthesis: Moving Away from Piperidine?

Molecules, 2016
The deprotection step is crucial in order to secure a good quality product in Fmoc solid phase peptide synthesis. 9-Fluorenylmethoxycarbonyl (Fmoc) removal is achieved by a two-step mechanism reaction favored by the use of cyclic secondary amines ...
Omar F. Luna, Johana Gomez, Constanza Cárdenas, Fernando Albericio, Sergio H. Marshall, Fanny Guzmán   +5 more
doaj   +1 more source

Catalytic asymmetric synthesis of the alkaloid (+)-myrtine [PDF]

, 2008
A new protocol for the asymmetric synthesis of trans-2,6-disubstituted-4-piperidones has been developed using a catalytic enantioselective conjugate addition reaction in combination with a diastereoselective lithiation–substitution sequence; an efficient
Adriaan J. Minnaard, Albrow, Alexakis, Alexakis, Anderson, Bach, Back, Beak, Beak, Beak, Beak, Beak, Beak, Beak, Ben L. Feringa, Bennett, Bennett, Berkheij, Bertini Gross, Brooks, Comins, Comins, Comins, Comins, Comins, Comins, Comins, Curtin, d'Augustin, Davis, Dieter, Dieter, Dieter, Dieter, Dieter, Eilitz, Frankel, Fraser, Gallagher, Garcia-Ruiz, Gardette, Gelas-Mialhe, Hoffmann, Houk, Kerrick, King, Leclercq, Liang, Maria Gabriella Pizzuti, Pilli, Pilli, Pineschi, Pàmies, Remuson, Slosse, Slosse, Still, Tawara, Vuagnoux-d'Augustin, Vuagnoux-d'Augustin, Watson, Whisler, Šebesta   +62 more
core   +1 more source

Synthesis, docking, pharmacokinetic prediction, and acetylcholinesterase inhibitory evaluation of N-(2-(piperidine-1-yl)ethyl)benzamide derivatives as potential anti-Alzheimer agents

Research in Pharmaceutical Sciences
Background and purpose: Alzheimer’s disease is the most common form of dementia and the sixth most common cause of death in the US according to the Alzheimer’s Association.
Ahmad Mohammadi-Farani, Farzaneh Moradi, Amin Hosseini, Alireza Aliabadi   +3 more
doaj   +1 more source

Pd-catalyzed enantioselective aerobic oxidation of secondary alcohols: Applications to the total synthesis of alkaloids [PDF]

, 2008
Enantioselective syntheses of the alkaloids (-)-aurantioclavine, (+)-amurensinine, (-)-lobeline, and (-)- and (+)-sedamine are described. The syntheses demonstrate the effectiveness of the Pd-catalyzed asymmetric oxidation of secondary alcohols in ...
Bagdanoff, Jeffrey T., Ebner, David C., Krishnan, Shyam, Ramtohul, Yeeman K., Stoltz, Brian M., Tambar, Uttam K.   +5 more
core   +2 more sources

Liesegang patterns: Effect of dissociation of the invading electrolyte

, 1998
The effect of dissociation of the invading electrolyte on the formation of Liesegang bands is investigated. We find, using organic compounds with known dissociation constants, that the spacing coefficient, 1+p, that characterizes the position of the n-th
Antal T., Chopard B., Dee G. T., Dhar N. R., Feeney R., Flicker M., Gálfi L., Henisch H. K., Jablczynski K., Kai S., Liesegang R. E., Matalon R., Morse W., Ostwald W., Packter A., Prager S., Shinohara S., Smith D. A., Venzl G., Wagner C., Zeldovitch Ya. B., Zrinyi M.   +21 more
core   +1 more source

Scope and Limitations of γ-Valerolactone (GVL) as a Green Solvent to be Used with Base for Fmoc Removal in Solid Phase Peptide Synthesis

Molecules, 2019
GVL is a green solvent used in Fmoc-based solid-phase peptide synthesis. It is susceptible to ring opening in the presence of bases such as piperidines, which are used to remove the Fmoc protecting group.
Ashish Kumar, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio   +3 more
doaj   +1 more source

A COLOR TEST FOR CERTAIN PIPERIDINE AND PYRROLIDINE ALKALOIDS [PDF]

, 1960
D. J. McCaldin
openalex   +1 more source

5′′-(4-Chlorobenzylidene)-4′-(4-chlorophenyl)-5-fluoro-1′,1′′-dimethylindoline-3-spiro-2′-pyrrolidine-3′-spiro-3′′-piperidine-2,4′′-dione [PDF]

, 2011
Jeyaperumal Kalyana Sundar, Brij Bala, S. Natarajan, J. Suresh, P. L. Nilantha Lakshman   +4 more
openalex   +1 more source

Easier, Safer, and Greener: Unlocking the Power of Solid Reagents in Organic Reactions by Mechanochemistry

ChemistryEurope, EarlyView.
This review highlights the powerful synergy between mechanochemistry and solid reagents to replace hazardous substances traditionally used in organic synthesis. Such an approach offers a safer and more sustainable pathway for conducting organic reactions, with potential benefits in both reactivity and selectivity. The use of solid bases, acids, and gas
Adrien Gallego, Nicolas Pétry, Julien Pinaud, Olivia Giani, Frédéric Lamaty   +4 more
wiley   +1 more source