Results 71 to 80 of about 76,241 (267)

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

Advanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty, Kamal el Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs. Szigyártó, Loránd Románszki, Natália Tőkési, Daniel Pinkas, Eszter Házy, Olivér Pavela, Andrea Bodor, Zoltán Varga, István Mándity, Mihály Kovács, Csaba Pál, Kata Horváti, Judit Tóth, Tamás Beke‐Somfai   +21 more
wiley   +1 more source

(2,4-Dichlorophenyl)(3-hydroxypiperidin-1-yl)methanone: crystal structure and Hirshfeld analysis

IUCrData, 2017
In the title compound, C12H13Cl2NO2, the piperidine ring adopts a chair conformation. The dihedral angle between the mean plane of the piperidine ring and the benzene ring is 58.5 (3)°.
U. Mohamooda Sumaya, D. Reuben Jonathan, Dravida Thendral Era, S. Gomathi, G. Usha   +4 more
doaj   +1 more source

Base-catalyzed reactions of environmentally relevant N-chloro-piperidines. A quantum-chemical study [PDF]

, 2011
Electronic structure methods have been applied to calculate the gas and aqueous phase reaction energies for base-induced rearrangements of N-chloropiperidine, N-chloro-3-(hydroxymethyl)piperidine, and N-chloro-4-4-fluorophenyl)-3-(hydroxymethyl ...
Sakic, Davor, Vrcek, Valerije, Zipse, Hendrik   +2 more
core   +1 more source

Sugar‐Armored Pesticides: Self‐Assembled System for Enhanced Foliar Adhesion and Sustained Delivery of Hydrophobic Antimicrobials Against Bacterial Diseases

Advanced Science, EarlyView.
This study develops a sugar‐armored, self‐assembled pesticide delivery system that enhances foliar adhesion, provides sustained release, effectively disrupts biofilms, and demonstrates superior bactericidal activity for improved disease control.
Jinghan Yang, Juan Liu, Xiaohui Wang, Peiyi Wang   +3 more
wiley   +1 more source

Crystal structure of 3-methyl-2,6-bis(4-methyl-1,3-thiazol-5-yl)piperidin-4-one

Acta Crystallographica Section E, 2014
In the title compound, C14H17N3OS2, the central piperidinone ring adopts a chair conformation and the thiazole rings are inclined to its mean plane by 80.16 (12) and 67.15 (12)°.
A. Manimaran, K. Sethusankar, S. Ganesan, S. Ananthan   +3 more
doaj   +1 more source

Sodium piperidine-1-carbodithioate dihydrate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
The asymmetric unit of the title compound, Na(+)·C(6)H(10)NS(2) (-)·2H(2)O, is composed of a sodium cation, a piperidine-dithio-carbamate anion which exhibits positional disorder, and two lattice water mol-ecules. The atoms of the piperidine ring are divided over two sites with occupancy factors of 0.554 (6) and 0.446 (6).
Ana C. Mafud, Maria Teresa P. Gambardella   +1 more
openaire   +3 more sources

Self-assembly of Fmoc-tetrapeptides based on the RGDS cell adhesion motif [PDF]

, 2011
Self-assembly in aqueous solution has been investigated for two Fmoc [Fmoc ¼ N-(fluorenyl)-9-methoxycarbonyl] tetrapeptides comprising the RGDS cell adhesion motif from fibronectin or the scrambled sequence GRDS.
Alemán, Carlos, Castelletto, Valeria, Cheng, Ge, Hamley, Ian W., Hicks, Matthew R., López-Pérez, Daniel E., Moulton, Claire M., Revilla-López-Pérez, Guillermo, Rodger, Alison   +8 more
core   +1 more source

Dual Effect of Steric Hindrance in Non‐Aqueous Amine Absorbents: Navigating the Trade‐Off Between Kinetics and Thermodynamics for Efficient CO2 Capture

Advanced Science, EarlyView.
This study elucidates how steric hindrance in amines creates a dual effect in CO2 capture: it thermodynamically favors the reaction by shifting the pathway from carbamate to alkyl carbonate formation, increasing capacity and lowering regeneration heat, while simultaneously slightly slowing the kinetics.
Xiaoyi Gao, Bin Xu, Xi Tang, Muyi Li, Cong Luo, Fan Wu, Xiaoshan Li, Liqi Zhang, Wen Chen   +8 more
wiley   +1 more source

Phenylpropionamides, Piperidine, and Phenolic Derivatives from the Fruit of Ailanthus altissima

Molecules, 2017
Four novel compounds—two phenylpropionamides, one piperidine, and one phenolic derivatives—were isolated and identified from the fruit of a medicinal plant, Ailanthus altissima (Mill.) Swingle (Simaroubaceae), together with one known phenylpropionamide ...
Jian-Cheng Ni, Jian-Ting Shi, Qing-Wei Tan, Qi-Jian Chen   +3 more
doaj   +1 more source

Synthetic Studies Towards Darobactin A. [PDF]

Chemistry
The urgent need for new antibiotics led us to develop a new methodology for the synthesis of the natural product darobactin A selectively targeting gram‐negative bacteria. This study provides new insights into the synthesis of strained indole‐containing macrocycles.
Steiner T, Versini A, Schellenberg M, Schuler E, Gademann K.   +4 more
europepmc   +2 more sources