Results 71 to 80 of about 37,707 (289)

Crystal structure of 3-methyl-2,6-bis(4-methyl-1,3-thiazol-5-yl)piperidin-4-one

Acta Crystallographica Section E, 2014
In the title compound, C14H17N3OS2, the central piperidinone ring adopts a chair conformation and the thiazole rings are inclined to its mean plane by 80.16 (12) and 67.15 (12)°.
A. Manimaran, K. Sethusankar, S. Ganesan, S. Ananthan   +3 more
doaj   +1 more source

A Universal Approach to Anchoring Chromophores onto Magnetic Scaffold for Achieving Easily Recyclable Heterogeneous Photocatalytic Systems

Advanced Science, EarlyView.
The practical application of chromophores such as porphyrins, coumarins, anthraquinones, and pyrene derivatives in photocatalysis is severely limited by catalyst stability and reusability. In this work, a simple and universal strategy is presented for preparing highly efficient and recyclable heterogeneous photocatalysts for the oxidative coupling of ...
Xuan Zhan, Yikun Wang, Chenyang Sun, Yuchen Fang, Lihua Huang, Zakir Ullah, Qiang Chen, Xuejing Wang, Zheng Xing, Gangfeng Ouyang   +9 more
wiley   +1 more source

Transaminase‐Triggered Cascades for the Synthesis and Dynamic Kinetic Resolution of Chiral N‐Heterocycles

Angewandte Chemie, EarlyView.
A single‐step biocatalytic route to complex indolizidine and quinolizidine alkaloids is described that relies on transaminase‐triggered double intramolecular aza‐Michael methodology. In one case, a retro‐double intramolecular aza‐Michael reaction enables dynamic kinetic resolution. Abstract Biocatalysis is now a well‐established branch of catalysis and
Adam O'Connell, Marianne B. Haarr, James Ryan, Xingxing Xu, Aoife Martin, Simon N. Smith, Nadia Elghobashi‐Meinhardt, Patricia Fleming, Beatriz Maciá, Vittorio Caprio, Elaine O'Reilly   +10 more
wiley   +2 more sources

Crystal structure and Hirshfeld surface analysis of N-(4-nitrophenyl)-2-(piperidin-1-yl)acetamide (lidocaine analogue)

Acta Crystallographica Section E: Crystallographic Communications
In the title molecule, C13H17N3O3, the substituents on the phenyl ring are rotated slightly out of the mean plane of the ring but the piperidine moiety is nearly perpendicular to that plane. In the crystal, C—H...O hydrogen bonds form chains of molecules
Imane Maimoune, Benson M. Kariuki, Abderrazzak El Moutaouakil Ala Allah, Intissar Nchioua, Abdulsalam Alsubari, Joel T. Mague, Abdelkader Zarrouk, Youssef Ramli   +7 more
doaj   +1 more source

Synthesis and in vivo anti-ulcer evaluation of some novel piperidine linked dihydropyrimidinone derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Dihydropyrimidinone derivatives containing piperidine moiety were synthesised in a good yield. All the compounds were confirmed by elemental analysis and spectral data.
Mashooq Ahmad Bhat, Mohamed A. Al-Omar, Ahmed M. Naglah   +2 more
doaj   +1 more source

Synthesis and Pharmacology of Ester Modified (+/-)-threo-Methylphenidate Analogs [PDF]

arXiv, 2014
As part of a program to develop compounds with potential to treat cocaine abuse, eleven (+/-)-threo-methylphenidate (TMP; Ritalin) derivatives were synthesized and tested in rat striatal tissue preparations for inhibitory potency against [3H]WIN 35,428 binding (WIN) to the dopamine (DA) transporter, [3H]citalopram binding (CIT) to the serotonin ...
arxiv  

High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics

Advanced Science, EarlyView.
The systematic tiling of essential genes’ mRNA here presented, proposes a valuable tool for the identification of novel PNA sequences with antibiotic potential. The high‐throughput synthetic set up opens the door to investigating thousands of sequences in an economic way and ultimately identifies potent antisense oligonucleotides while also giving room
Giorgia Danti, Linda Popella, Jörg Vogel, Hans M. Maric   +3 more
wiley   +1 more source

Chemical Bonds Containing Hydrogen: Choices for Hydrogen Carriers and Catalysts

Angewandte Chemie, EarlyView.
Hydrogen carriers utilizing B─H, C─H, N─H, and O─H bonds are evaluated for their potential in hydrogen storage and release. Key candidates such as methanol, ammonia, and formic acid are examined with a focus on critical factors influencing performance, including the nature of chemical bonds, reaction pathways, and catalytic processes.
James Cashel, Dai Yan, Rui Han, Hyangsoo Jeong, Chang Won Yoon, John Arnold Ambay, Yongfeng Liu, Alison T. Ung, Limei Yang, Zhenguo Huang   +9 more
wiley   +2 more sources

Phenylpropionamides, Piperidine, and Phenolic Derivatives from the Fruit of Ailanthus altissima

Molecules, 2017
Four novel compounds—two phenylpropionamides, one piperidine, and one phenolic derivatives—were isolated and identified from the fruit of a medicinal plant, Ailanthus altissima (Mill.) Swingle (Simaroubaceae), together with one known phenylpropionamide ...
Jian-Cheng Ni, Jian-Ting Shi, Qing-Wei Tan, Qi-Jian Chen   +3 more
doaj   +1 more source

Synthetic route towards potential bivalent ligands possessing opioid and D2/D3 pharmacophores [PDF]

Journal of the Serbian Chemical Society, 2019
A scalable, cost-efficient and simple synthetic pathway towards potential bivalent opioid/dopamine receptor ligands was developed and optimized. Three novel compounds that contain both opioid and dopamine pharmacophores linked by the four methylene group
Jevtić Ivana I., Penjišević Jelena Z., Ivanović Milovan D., Kostić-Rajačić Slađana V.   +3 more
doaj   +1 more source