Results 51 to 60 of about 52,734 (205)

Scope and Limitations of γ-Valerolactone (GVL) as a Green Solvent to be Used with Base for Fmoc Removal in Solid Phase Peptide Synthesis

Molecules, 2019
GVL is a green solvent used in Fmoc-based solid-phase peptide synthesis. It is susceptible to ring opening in the presence of bases such as piperidines, which are used to remove the Fmoc protecting group.
Ashish Kumar, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio   +3 more
doaj   +1 more source

An Experimental and Computational Investigation of the Enantioselective Deprotonation of Boc-piperidine

, 2016
The asymmetric deprotonation of N-Boc-piperidine (3) by the 1:1 complex of a sec-alkyllithium and (−)-sparteine has been investigated both experimentally and computationally.
Kenneth B. Wiberg (1510459), Sunghoon Ma (2074120), Peter Beak (2402176), William F. Bailey (1617169), Shawn T. Kerrick (2985984)   +4 more
core   +1 more source

A Novel Synthesis of the Efficient Anti-Coccidial Drug Halofuginone Hydrobromide

Molecules, 2017
Background: Halofuginone hydrobromide (1) is recognized as an effective drug against several species of Eimeria (E.) in poultry. In this paper, we describe a convenient and low cost preparation method for the compound, as well as primary validation of ...
Junren Zhang, Qizheng Yao, Zuliang Liu
doaj   +1 more source

N-(2-Hydroxyethyl)piperidine [PDF]

The German Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission) summarized and evaluated the data for N-(2-hydroxyethyl)piperidine [3040-44-6] to derive an occupational exposure limit value ...
Hartwig, Andrea; https://orcid.org/, Arand, Michael; https://orcid.org/, MAK Commission   +2 more
core   +1 more source

The crystal structures of 6′-(4-chlorophenyl)- and 6′-(4-methoxyphenyl)-6a′-nitro-6a′,6b′,7′,9′,10′,12a′-hexahydro-2H,6′H,8′H-spiro[acenaphthylene-1,12′-chromeno[3,4-a]indolizin]-2-one

Acta Crystallographica Section E: Crystallographic Communications, 2019
In the title compounds, C32H25ClN2O4 (I) and C33H28N2O5 (II), the six-membered pyran and piperidine rings adopt envelope and chair conformations, respectively. The five-membered pyrrolidine rings adopt twist conformations. Compound (II) crystallizes with
S. Syed Abuthahir, M. NizamMohideen, V. Viswanathan, D. Velmurugan, J. Nagasivarao   +4 more
doaj   +1 more source

A Ruthenium-Catalyzed Pyrrolidine and Piperidine Synthesis

, 2016
A Ruthenium-Catalyzed Pyrrolidine and Piperidine ...
Barry M. Trost (1309395), Anthony B. Pinkerton (1346583), Doris Kremzow (2983095)   +2 more
core   +1 more source

Crystal structure of (4-chlorophenyl)(4-methylpiperidin-1-yl)methanone

Acta Crystallographica Section E: Crystallographic Communications, 2020
The title compound, C13H16ClNO, contains a methylpiperidine ring in the stable chair conformation. The mean plane of the twisted piperidine ring subtends a dihedral angle of 39.89 (7)° with that of the benzene ring.
J. Srividya, D. Reuben Jonathan, B. K. Revathi, M. Divya Bharathi, G. Anbalagan   +4 more
doaj   +1 more source

Synthetic route towards potential bivalent ligands possessing opioid and D2/D3 pharmacophores [PDF]

Journal of the Serbian Chemical Society, 2019
A scalable, cost-efficient and simple synthetic pathway towards potential bivalent opioid/dopamine receptor ligands was developed and optimized. Three novel compounds that contain both opioid and dopamine pharmacophores linked by the four methylene group
Jevtić Ivana I., Penjišević Jelena Z., Ivanović Milovan D., Kostić-Rajačić Slađana V.   +3 more
doaj   +1 more source

tropane, piperidine & pyridine alkaloid biosynthesis-png

, 2014
unigenes associated with tropane, piperidine & pyridine alkaloid ...
Karen Fugate (480954)
core   +1 more source

tropane, piperidine & pyridine alkaloid biosynthesis-html

, 2014
unigenes associated with tropane, piperidine & pyridine alkaloid ...
Karen Fugate (480954)
core   +1 more source