Results 31 to 40 of about 38,755 (162)

3-Nitroso-2,4,6,8-tetraphenyl-3,7-diazabicyclo[3.3.1]nonan-9-one

Acta Crystallographica Section E, 2011
In the title compound, C31H27N3O2, the two piperidine rings fused to each other each adopt a slightly distorted chair conformation. The phenyl rings on the N-unsubstituted piperidine ring occupy an equatorial position, while those on the N-nitroso ...
Sampath Natarajan, Rita Mathews
doaj   +1 more source

Biological Activities and Ecological Significance of Fire Ant Venom Alkaloids

Toxins, 2023
Venoms produced by arthropods act as chemical weapons to paralyze prey or deter competitors. The utilization of venom is an essential feature in the biology and ecology of venomous arthropods.
Guangxin Xu, Li Chen
doaj   +1 more source

1-Dichloroacetyl-t-3-isopropyl-r-2,c-6-diphenylpiperidin-4-one

Acta Crystallographica Section E, 2013
In the title compound, C22H23Cl2NO2, the piperidine ring adopts a twist-boat conformation. The phenyl rings substituted at the 2- and 6-positions of the piperidine ring subtend dihedral angles of 60.6 (2) and 84.2 (1)°, respectively ...
M. N. Ponnuswamy, S. Ponnuswamy, R. Mini, R. Kayalvizhi, P. Sugumar   +4 more
doaj   +1 more source

1-Formyl-c-3,t-3-dimethyl-r-2,c-6-diphenylpiperidin-4-one

Acta Crystallographica Section E, 2012
In the title compound, C20H21NO2, the piperidine ring adopts a distorted boat conformation. The phenyl rings substituted at the 2- and 6-positions of the piperidine ring subtend angles of 86.0 (1) and 67.3 (1)° with the mean ...
S. Ponnuswamy, P. Ramesh, P. Sakthivel, K. Ravichandran, M. N. Ponnuswamy   +4 more
doaj   +1 more source

2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity

Pharmaceuticals, 2021
The pharmacological inhibition of soluble epoxide hydrolase (sEH) has been suggested as a potential therapy for the treatment of pain and inflammatory diseases through the stabilization of endogenous epoxyeicosatrienoic acids.
Juan Martín-López, Sandra Codony, Clara Bartra, Christophe Morisseau, María Isabel Loza, Coral Sanfeliu, Bruce D. Hammock, José Brea, Santiago Vázquez   +8 more
doaj   +1 more source

Scope and Limitations of γ-Valerolactone (GVL) as a Green Solvent to be Used with Base for Fmoc Removal in Solid Phase Peptide Synthesis

Molecules, 2019
GVL is a green solvent used in Fmoc-based solid-phase peptide synthesis. It is susceptible to ring opening in the presence of bases such as piperidines, which are used to remove the Fmoc protecting group.
Ashish Kumar, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio   +3 more
doaj   +1 more source

A Novel Synthesis of the Efficient Anti-Coccidial Drug Halofuginone Hydrobromide

Molecules, 2017
Background: Halofuginone hydrobromide (1) is recognized as an effective drug against several species of Eimeria (E.) in poultry. In this paper, we describe a convenient and low cost preparation method for the compound, as well as primary validation of ...
Junren Zhang, Qizheng Yao, Zuliang Liu
doaj   +1 more source

The crystal structures of 6′-(4-chlorophenyl)- and 6′-(4-methoxyphenyl)-6a′-nitro-6a′,6b′,7′,9′,10′,12a′-hexahydro-2H,6′H,8′H-spiro[acenaphthylene-1,12′-chromeno[3,4-a]indolizin]-2-one

Acta Crystallographica Section E: Crystallographic Communications, 2019
In the title compounds, C32H25ClN2O4 (I) and C33H28N2O5 (II), the six-membered pyran and piperidine rings adopt envelope and chair conformations, respectively. The five-membered pyrrolidine rings adopt twist conformations. Compound (II) crystallizes with
S. Syed Abuthahir, M. NizamMohideen, V. Viswanathan, D. Velmurugan, J. Nagasivarao   +4 more
doaj   +1 more source

Anticancer Applications and Pharmacological Properties of Piperidine and Piperine: A Comprehensive Review on Molecular Mechanisms and Therapeutic Perspectives

Frontiers in Pharmacology, 2022
Piperine and piperidine are the two major alkaloids extracted from black pepper (Piper nigrum); piperidine is a heterocyclic moiety that has the molecular formula (CH2)5NH.
Sicon Mitra, Uttpal Anand, Niraj Kumar Jha, Mahipal S. Shekhawat, Suchismita Chatterjee Saha, Potshangbam Nongdam, Kannan R. R. Rengasamy, Jarosław Proćków, Abhijit Dey   +8 more
doaj   +1 more source

Crystal structure of (4-chlorophenyl)(4-methylpiperidin-1-yl)methanone

Acta Crystallographica Section E: Crystallographic Communications, 2020
The title compound, C13H16ClNO, contains a methylpiperidine ring in the stable chair conformation. The mean plane of the twisted piperidine ring subtends a dihedral angle of 39.89 (7)° with that of the benzene ring.
J. Srividya, D. Reuben Jonathan, B. K. Revathi, M. Divya Bharathi, G. Anbalagan   +4 more
doaj   +1 more source