Results 31 to 40 of about 103,451 (274)

Novel chalcone-based fluorescent human histamine H 3 receptor ligands as pharmacological tools [PDF]

open access: yes, 2012
Novel fluorescent chalcone-based ligands at human histamine H(3) receptors (hH(3)R) have been designed, synthesized, and characterized. Compounds described are non-imidazole analogs of ciproxifan with a tetralone motif.
Tomasch, Miriam   +3 more
core   +1 more source

Ammonium piperidine-1-carbodithioate [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2011
The title compound, NH(4) (+)·C(6)H(10)NS(2) (-), is composed of an ammonium cation and a piperidine-1-carbodithio-ate anion which exhibits positional disorder. The atoms of the ring have a structural disorder and they are divided into two sites, with occupancy factors of 0.584 and 0.426..
Ana C. Mafud, Maria T. P. Gambardella
openaire   +3 more sources

Synthesis of hetero-bifunctional, end-capped oligo-EDOT derivatives [PDF]

open access: yes, 2016
Conjugated oligomers of 3,4-ethylenedioxythiophene (EDOT) are attractive materials for tissue engineering applications, and as model systems for studying the properties of the widely used polymer PEDOT.
Armgarth, A   +5 more
core   +4 more sources

Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element

open access: yesEuropean journal of medicinal chemistry, 2018
There are currently no approved vaccines or small molecule therapeutics available for the prophylaxis or treatment of Middle East Respiratory Syndrome coronavirus (MERS-CoV) infections.
Anushka C Galasiti Kankanamalage   +11 more
semanticscholar   +1 more source

Synthesis and biological evaluation of novel PDMP analogues [PDF]

open access: yes, 2006
A new series of hybrid PDMP analogues, based both on PDMP and styryl analogues of natural ceramide, has been synthesized from D-serine. The synthetic route was developed such that future introduction of different aryl groups is straightforward ...
Boldin-Adamsky, Swetlana   +5 more
core   +1 more source

Biological evaluation of a series of benzothiazole derivatives as mosquitocidal agents

open access: yesOpen Chemistry, 2019
Aedes aegypti is associated with the transmission of numerous human and animal diseases, such as yellow fever, dengue fever, chikungunya, and more recently Zika virus. Emerging insecticide resistance has created a need to develop new mosquitocidal agents
Sever Belgin   +6 more
doaj   +1 more source

Sonogashira/N-acyliminium ion aromatic π-cyclisation processes: access to tetra- and pentacyclic lactams [PDF]

open access: yes, 2008
Application of the Sonogashira reaction of N-alkynylimides with 2-iodophenol or 2-iodo-N-tosylaniline affords 2-(N-alkylimino)-benzofurans and indoles in good yield.
Grigg, R., Sridharan, V., Sykes, D.A.
core   +1 more source

Ammonium Salts of 5-(3-Chromenyl)-5H-chromeno[2,3-b]pyridines

open access: yesMolbank, 2021
The ammonium salts of many drugs have significantly improved the solubility and, accordingly, the bioavailability of medicinal substances in the human body.
Yuliya E. Ryzhkova   +2 more
doaj   +1 more source

Functionalization of Piperidine Derivatives for the Site‐Selective and Stereoselective Synthesis of Positional Analogues of Methylphenidate

open access: yesChemistry, 2019
Rhodium‐catalyzed C−H insertions and cyclopropanations of donor/acceptor carbenes have been used for the synthesis of positional analogues of methylphenidate. The site selectivity is controlled by the catalyst and the amine protecting group.

semanticscholar   +1 more source

(7,8-Dimethyl-2-oxo-2H-chromen-4-yl)methyl piperidine-1-carbodithioate

open access: yesIUCrData, 2016
In the title compound, C18H21NO2S2, the 2H-chromene ring systems is nearly planar, with a maximum deviation of 0.023 (2) Å. The coumarin unit makes a dihedral angle of 60.54 (8)° with the piperidine ring, which adopts a chair conformation.
A. J. Ravi   +2 more
doaj   +1 more source

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