Results 21 to 30 of about 13,079 (195)

Biological evaluation of a series of benzothiazole derivatives as mosquitocidal agents

Open Chemistry, 2019
Aedes aegypti is associated with the transmission of numerous human and animal diseases, such as yellow fever, dengue fever, chikungunya, and more recently Zika virus. Emerging insecticide resistance has created a need to develop new mosquitocidal agents
Sever Belgin, Altıntop Mehlika Dilek, Özdemir Ahmet, Tabanca Nurhayat, Estep Alden S., Becnel James J., Bloomquist Jeffrey R.   +6 more
doaj   +1 more source

1-(2,5-Dimethoxy-4-nitrophenyl)piperidine

, 2023
Treatment of the non-purified mixture of dinitro isomers obtained from the nitration of 1,4-dimethoxybenzene with piperidine led to the isolation of novel but minor adduct, 1-(2,5-dimethoxy-4-nitrophenyl)piperidine (2b) in 15% yield.
Basri, Ibtihal, AlDabbagh, Fawaz, Syeda, Tanjia M., Muadh R. Al-Shaidi, Ibtihal Basri, Tanjia M. Syeda, Mahboub Merzouk, Fawaz Aldabbagh, Al-Shaidi, Muadh R., Merzouk, Mahboub   +9 more
core   +1 more source

(7,8-Dimethyl-2-oxo-2H-chromen-4-yl)methyl piperidine-1-carbodithioate

IUCrData, 2016
In the title compound, C18H21NO2S2, the 2H-chromene ring systems is nearly planar, with a maximum deviation of 0.023 (2) Å. The coumarin unit makes a dihedral angle of 60.54 (8)° with the piperidine ring, which adopts a chair conformation.
A. J. Ravi, K. Mahesh Kumar, H. C. Devarajegowda   +2 more
doaj   +1 more source

Highly Enantiopure C₁-Symmetric cis-Piperidine-3,5-dimethanol Monoacetates by Enzymatic Asymmetrization¹

, 2016
Highly Enantiopure C1-Symmetric cis-Piperidine-3,5-dimethanol Monoacetates by Enzymatic ...
Alessandra Silvani (1493923), Daniele Passarella (129791), Bruno Danieli (2643796), Giordano Lesma (1493932)   +3 more
core   +1 more source

thrombin-Piperidine PDB file

, 2020
PDB file used for thrombin-piperidine ...
Stefan Doerr (748688)
core   +1 more source

Cobalt-Catalyzed (Hetero)arylation of Saturated Cyclic Amines with Grignard Reagents

Molecules, 2018
(Hetero)aryl substituted saturated cyclic amines are ubiquitous scaffolds in biologically active molecules. Metal-catalyzed cross-couplings between halogeno N-heterocycles and organometallic species are efficient and modular reactions to access these ...
Baptiste Barré, Laurine Gonnard, Amandine Guérinot, Janine Cossy   +3 more
doaj   +1 more source

Ultrasound-Assisted Synthesis of Piperidinyl-Quinoline Acylhydrazones as New Anti-Alzheimer’s Agents: Assessment of Cholinesterase Inhibitory Profile, Molecular Docking Analysis, and Drug-like Properties

Molecules, 2023
Alzheimer’s disease (AD) is one of the progressive neurological disorders and the main cause of dementia all over the world. The multifactorial nature of Alzheimer’s disease is a reason for the lack of effective drugs as well as a basis for the ...
Rubina Munir, Sumera Zaib, Muhammad Zia-ur-Rehman, Nadia Hussain, Faryal Chaudhry, Muhammad Tayyab Younas, Fatima Tuz Zahra, Zainab Tajammul, Noman Javid, Ayed A. Dera, Hanan A. Ogaly, Imtiaz Khan   +11 more
doaj   +1 more source

Synthesis and evaluation of α-fluoro analogues of capsaicin and 2-(aminomethyl)piperidine derivatives [PDF]

, 2011
Chapter 1 gives an overview of the fluorine chemistry field, from its early developments to recent applications in medicinal chemistry. The development of asymmetric electrophilic or nucleophilic installation of fluorine in organic molecules is ...
Moraux, Thomas
core   +2 more sources

When piperidine was a structural problem [PDF]

, 1998
The studies of methylation by August Hofmann and isolation of piperidine by Auguste Cahours in 1852 led to a direct synthesis of piperidine and discovery of its structure by Albert ...
Warnhoff, Edgar W.
core   +1 more source

Synthesis of Substituted α-Trifluoromethyl Piperidinic Derivatives

Molecules, 2017
A comprehensive survey of pathways leading to the generation of α-trifluoromethyl monocyclic piperidinic derivatives is provided (65 references).
Sarah Rioton, Domingo Gomez Pardo, Janine Cossy   +2 more
doaj   +1 more source