Results 21 to 30 of about 38,755 (162)

Microwave-Assisted Synthesis, Structural Characterization and Assessment of the Antibacterial Activity of Some New Aminopyridine, Pyrrolidine, Piperidine and Morpholine Acetamides

Molecules, 2021
A series of new acetamide derivatives 22–28 of primary and secondary amines and para-toluene sulphinate sodium salt have been synthesized under microwave irradiation and assessed in vitro for their antibacterial activity against one Gram-positive and two
Abdulmajeed S. H. Alsamarrai, Saba S. Abdulghani   +1 more
doaj   +1 more source

PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines

Beilstein Journal of Organic Chemistry, 2011
PEG-embedded potassium tribromide ([K+PEG]Br3−) was found to be an efficient and recyclable catalyst for the synthesis of functionalized piperidines in high yields in a one step, three component coupling between aldehyde, amine and β-keto ester.
Sanny Verma, Suman L. Jain, Bir Sain
doaj   +1 more source

Crystal structure and Hirshfeld surface analysis of N-(4-nitrophenyl)-2-(piperidin-1-yl)acetamide (lidocaine analogue)

Acta Crystallographica Section E: Crystallographic Communications
In the title molecule, C13H17N3O3, the substituents on the phenyl ring are rotated slightly out of the mean plane of the ring but the piperidine moiety is nearly perpendicular to that plane. In the crystal, C—H...O hydrogen bonds form chains of molecules
Imane Maimoune, Benson M. Kariuki, Abderrazzak El Moutaouakil Ala Allah, Intissar Nchioua, Abdulsalam Alsubari, Joel T. Mague, Abdelkader Zarrouk, Youssef Ramli   +7 more
doaj   +1 more source

Crystal structure of 4-chloro-N-{[1-(4-chlorobenzoyl)piperidin-4-yl]methyl}benzamide monohydrate

Acta Crystallographica Section E, 2014
In the title compound, C20H20Cl2N2O2·H2O, the piperidine ring adopts a chair conformation with the two substituent benzene rings inclined to one another [dihedral angle 84.63 (9)°].
K. Prathebha, D. Reuben Jonathan, S. Sathya, J. Jovita, G. Usha   +4 more
doaj   +1 more source

Design and synthesis of various 1,3,4-oxadiazoles as AChE and LOX enzyme inhibitors

Heterocyclic Communications, 2023
N-Substituted-2-propanamide analogues of 1,3,4-oxadiazole have been synthesized using a multi-step synthetic protocol to explore new therapeutic anti-enzymatic agents.
Iqbal Javed, Mallhi Ali Imran, ur Rehman Aziz, Al-Mijalli Samiah H., un-Nisa Mehr, Zafar Fatiqa, Shahzad Sohail, Rasool Shahid, Iqbal Munawar, Shah Syed Adnan Ali   +9 more
doaj   +1 more source

Synthesis of a novel analogue of DPP-4 inhibitor Alogliptin: Introduction of a spirocyclic moiety on the piperidine ring

Beilstein Journal of Organic Chemistry, 2010
We report the synthesis of a novel analogue of Alogliptin via condensation of two key intermediates one of which is an aminopiperidine derivative bearing a spirocyclic ring on the piperidine moiety.
Arumugam Kodimuthali, Padala Lakshmi Prasunamba, Manojit Pal   +2 more
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The crystal structure and Hirshfeld surface analysis of 1-(2,5-dimethoxyphenyl)-2,2,6,6-tetramethylpiperidine

Acta Crystallographica Section E: Crystallographic Communications, 2020
In the title compound, C17H27NO2, the piperidine ring has a chair conformation and is positioned normal to the benzene ring. In the crystal, molecules are linked by C—H...O hydrogen bonds, forming chains propagating along the c-axis direction.
Mustapha Tiouabi, Raphaël Tabacchi, Helen Stoeckli-Evans   +2 more
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Synthesis and Antimalarial Activity of 1,4-Disubstituted Piperidine Derivatives

Molecules, 2020
In order to prepare, at low cost, new compounds active against Plasmodium falciparum, and with a less side-effects, we have designed and synthesized a library of 1,4-disubstituted piperidine derivatives from 4-aminopiperidine derivatives 6. The resulting
Rokhyatou Seck, Abdoulaye Gassama, Sandrine Cojean, Christian Cavé   +3 more
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r-2,c-6-Diphenylpiperidine

Acta Crystallographica Section E, 2013
In the title compound, C17H19N, the piperidine ring adopts a chair conformation. The phenyl rings substituted at the 2- and 6-positions of the piperidine ring subtend dihedral angles of 81.04 (7) and 81.10 (7)° with the best plane of the
V. Maheshwaran, S. Abdul Basheer, A. Akila, S. Ponnuswamy, M. N. Ponnuswamy   +4 more
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Crystal structures of five halido gold complexes involving piperidine or pyrrolidine as ligands or (protonated) as cations

Acta Crystallographica Section E: Crystallographic Communications, 2023
In bromido(pyrrolidine-κN)gold(I) bis(pyrrolidine-κN)gold(I) bromide, [AuBr(pyr)]·[Au(pyr)2]Br (pyr = pyrrolidine, C4H9N), 2, alternating [AuBr(pyr)] molecules and [Au(pyr)2]+ cations are connected by aurophilic contacts to form infinite chains of ...
Cindy Döring, Peter G. Jones
doaj   +1 more source