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PIPERIDINE : A CORRECTION. [PDF]

open access: yesThe Lancet, 1898
n ...
Tunnicliffe, F. W., Rosenheim, Otto
openaire   +2 more sources

Beyond the Simple Copper(II) Coordination Chemistry with Quinaldinate and Secondary Amines

open access: yesMolecules, 2020
Copper(II) acetate has reacted in methanol with quinaldinic acid (quinoline-2-carboxylic acid) to form [Cu(quin)2(CH3OH)]∙CH3OH (1) (quin− = an anionic form of the acid) with quinaldinates bound in a bidentate chelating manner.
Barbara Modec, Nina Podjed, Nina Lah
doaj   +1 more source

Overview of Piperidine and Morpholine Derivatives as Promising Sources of Biologically Active Compounds (Review)

open access: yesРазработка и регистрация лекарственных средств, 2023
Introduction. The search for new, effective and safe pharmacologically active substances remains an urgent task in the field of pharmacy. Many compounds of the piperidine and morpholine series are widely used in medical practice and belong to an ...
A. E. Khamitova, D. A. Berillo
doaj   +1 more source

The Stereoselective Nitro-Mannich Reaction in the Synthesis of Active Pharmaceutical Ingredients and Other Biologically Active Compounds

open access: yesFrontiers in Chemistry, 2020
The nitro-Mannich (aza-Henry) reaction, in which a nitroalkane and an imine react to form a β-nitroamine, is a versatile tool for target-oriented synthesis. Although the first stereoselective reaction was developed only 20 years ago, and enantioselective
Ana Maria Faisca Phillips   +2 more
doaj   +1 more source

The crystal structures, Hirshfeld surface analyses and energy frameworks of 8-{1-[3-(cyclopent-1-en-1-yl)benzyl]piperidin-4-yl}-2-methoxyquinoline and 8-{4-[3-(cyclopent-1-en-1-yl)benzyl]piperazin-1-yl}-2-methoxyquinoline

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2021
The title compounds, 8-{1-[3-(cyclopent-1-en-1-yl)benzyl]piperidin-4-yl}-2-methoxyquinoline, C27H30N2O (I), and 8-{4-[3-(cyclopent-1-en-1-yl)benzyl]piperazin-1-yl}-2-methoxyquinoline, C26H29N3O (II), differ only in the nature of the central six-membered ...
Nisar Ullah, Helen Stoeckli-Evans
doaj   +1 more source

Biological evaluation of a series of benzothiazole derivatives as mosquitocidal agents

open access: yesOpen Chemistry, 2019
Aedes aegypti is associated with the transmission of numerous human and animal diseases, such as yellow fever, dengue fever, chikungunya, and more recently Zika virus. Emerging insecticide resistance has created a need to develop new mosquitocidal agents
Sever Belgin   +6 more
doaj   +1 more source

(7,8-Dimethyl-2-oxo-2H-chromen-4-yl)methyl piperidine-1-carbodithioate

open access: yesIUCrData, 2016
In the title compound, C18H21NO2S2, the 2H-chromene ring systems is nearly planar, with a maximum deviation of 0.023 (2) Å. The coumarin unit makes a dihedral angle of 60.54 (8)° with the piperidine ring, which adopts a chair conformation.
A. J. Ravi   +2 more
doaj   +1 more source

1-[(3-Nitrophenyl)(piperidin-1-yl)methyl]piperidine [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2012
In the crystal structure of the title compound, C17H25N3O2, one-dimensional chains are formed via intermolecular C—H...O hydrogen bonds along the a axis.
Zhe-Qin Wang, Yi Ma
openaire   +3 more sources

Ultrasound-Assisted Synthesis of Piperidinyl-Quinoline Acylhydrazones as New Anti-Alzheimer’s Agents: Assessment of Cholinesterase Inhibitory Profile, Molecular Docking Analysis, and Drug-like Properties

open access: yesMolecules, 2023
Alzheimer’s disease (AD) is one of the progressive neurological disorders and the main cause of dementia all over the world. The multifactorial nature of Alzheimer’s disease is a reason for the lack of effective drugs as well as a basis for the ...
Rubina Munir   +11 more
doaj   +1 more source

Cobalt-Catalyzed (Hetero)arylation of Saturated Cyclic Amines with Grignard Reagents

open access: yesMolecules, 2018
(Hetero)aryl substituted saturated cyclic amines are ubiquitous scaffolds in biologically active molecules. Metal-catalyzed cross-couplings between halogeno N-heterocycles and organometallic species are efficient and modular reactions to access these ...
Baptiste Barré   +3 more
doaj   +1 more source

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