Results 11 to 20 of about 103,451 (274)

Anticancer Applications and Pharmacological Properties of Piperidine and Piperine: A Comprehensive Review on Molecular Mechanisms and Therapeutic Perspectives

open access: yesFrontiers in Pharmacology, 2022
Piperine and piperidine are the two major alkaloids extracted from black pepper (Piper nigrum); piperidine is a heterocyclic moiety that has the molecular formula (CH2)5NH.
Sicon Mitra   +8 more
doaj   +2 more sources

Deprotection Reagents in Fmoc Solid Phase Peptide Synthesis: Moving Away from Piperidine?

open access: yesMolecules, 2016
The deprotection step is crucial in order to secure a good quality product in Fmoc solid phase peptide synthesis. 9-Fluorenylmethoxycarbonyl (Fmoc) removal is achieved by a two-step mechanism reaction favored by the use of cyclic secondary amines ...
Omar F. Luna   +5 more
doaj   +2 more sources

Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications

open access: yesInternational Journal of Molecular Sciences, 2023
Piperidines are among the most important synthetic fragments for designing drugs and play a significant role in the pharmaceutical industry. Their derivatives are present in more than twenty classes of pharmaceuticals, as well as alkaloids.
N. Frolov, A. Vereshchagin
semanticscholar   +1 more source

Functionalizing Polystyrene with N-Alicyclic Piperidine-Based Cations via Friedel–Crafts Alkylation for Highly Alkali-Stable Anion-Exchange Membranes

open access: yesMacromolecules, 2020
Different anion-exchange membranes (AEMs) based on polystyrene (PS)-carrying benzyltrimethyl ammonium cations are currently being developed for use in alkaline fuel cells and water electrolyzers.
J. Olsson, Thanh Huong Pham, P. Jannasch
semanticscholar   +1 more source

Synthesis and biological evaluation of novel quinoline-piperidine scaffolds as antiplasmodium agents

open access: yesEuropean journal of medicinal chemistry, 2020
The parasitic disease malaria places almost half of the world’s population at risk of infection and is responsible for more than 400,000 deaths each year.
Tim Van de Walle   +7 more
semanticscholar   +1 more source

Beyond the Simple Copper(II) Coordination Chemistry with Quinaldinate and Secondary Amines

open access: yesMolecules, 2020
Copper(II) acetate has reacted in methanol with quinaldinic acid (quinoline-2-carboxylic acid) to form [Cu(quin)2(CH3OH)]∙CH3OH (1) (quin− = an anionic form of the acid) with quinaldinates bound in a bidentate chelating manner.
Barbara Modec, Nina Podjed, Nina Lah
doaj   +1 more source

Overview of Piperidine and Morpholine Derivatives as Promising Sources of Biologically Active Compounds (Review)

open access: yesРазработка и регистрация лекарственных средств, 2023
Introduction. The search for new, effective and safe pharmacologically active substances remains an urgent task in the field of pharmacy. Many compounds of the piperidine and morpholine series are widely used in medical practice and belong to an ...
A. E. Khamitova, D. A. Berillo
doaj   +1 more source

The mechanism of pyridine hydrogenolysis on molybdenum-containing catalysts : IV. The conversion of piperidine [PDF]

open access: yes, 1973
The conversion of piperidine was investigated on a CoO-MoO3-Al2O3 catalysts as a function of the temperature, reaction time, initial piperidine partial pressure and the hydrogen pressure.\ud \ud At 60 atm of hydrogen and conversions below 50% piperidine ...
Mars, P., Neyens, W.J., Sonnemans, J.
core   +2 more sources

Pot, atom and step economic (PASE) synthesis of highly functionalized piperidines: a five-component condensation [PDF]

open access: yes, 2007
The diastereoselective pot, atom and step economic (PASE) synthesis of highly functionalized piperidines has been realized. The procedure simply involves mixing methyl acetoacetate, 2 equiv of aldehyde and 2 equiv of aniline together in the presence of ...
Clarke, Paul A.   +2 more
core   +1 more source

Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA [PDF]

open access: yes, 1987
Forms of the DNA double helix containing non-Watson-Crick base-pairing have been discovered recently based on x-ray diffraction analysis of quinoxaline antibiotic-oligonucleotide complexes.
Dervan, Peter B., Mendel, David
core   +2 more sources

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