Results 61 to 70 of about 52,734 (205)

Pharmacological and biochemical characteristics of blood of different groups of animals during treatment piperidine 2-(5-furan-2-yl)-4-phenyl-1,2,4-triazol-3-iltioatsetat

Zaporožskij Medicinskij Žurnal, 2013
A study of blood biochemical parameters of different groups of animals on a background of piperidine 2 - (5-furan-2-yl)-4-phenyl-1,2,4-triazol-3-iltioatsetat.
V. V. Parchenko , L. I. Parhomenko, V. Y. Izdepsky   +2 more
doaj   +1 more source

Synthesis and Characterization of New Functionalized Pyrimidine (Hetero)Cyclic Molecular Hybrids as Chiral Heterocyclic Amino Acid Derivatives

Molecules
Heterocyclic unnatural amino acids and their biheterocyclic derivatives represent invaluable structural scaffolds in modern medicinal chemistry and peptidomimetics due to their ability to induce conformational constraints and modulate pharmacokinetic ...
Paulina Voznikaitė, Greta Račkauskienė, Miglė Dagilienė, Vilija Kederienė, Frank A. Sløk, Algirdas Šačkus   +5 more
doaj   +1 more source

(3-Hydroxypiperidin-1-yl)(4-methylphenyl)methanone

IUCrData, 2017
In the title molecule, C13H17NO2, the piperidine ring assumes a chair conformation. The dihedral angle between the mean plane of the piperidine ring and the benzene ring is 45.49 (1)°.
S. Gomathi, D. Reuben Jonathan, U. Mohamooda Sumaya, E. R. A. Dravida Thendral, G. Usha   +4 more
doaj   +1 more source

Asymmetric piperidine synthesis [PDF]

It has been demonstrated that bakers' yeast reduction of 1-tert-butyl-2-methyl 3-oxo-piperidine-1,2-dicarboxylate gives (2R, 3S), 1-tert-butyl-2-methyl 3-hydroxy-piperidine-1,2-dicarboxylate in 80% chemical yield with >99% d.e. and >97% e.e. Also bakers'
Lewis, Neil
core  

Levels Of Endogenous Piperidine Studied In Active And Dormant Hamsters [PDF]

, 1975
Methods for detection and micro-quantitation of endogenous piperidine were applied for the first time to brain tissue of sleeping and active hamsters. Piperidine levels in dormant hamsters were over three times that of active hamsters.
Frantela, Stephen
core  

Crystal structures of two chiral piperidine derivatives: 1-[(1R)-2-hydroxy-1-phenylethyl]piperidin-4-one and 8-[(1S)-1-phenylethyl]-1,4-dioxa-8-azaspiro[4.5]decane-7-thione

Acta Crystallographica Section E: Crystallographic Communications, 2015
The crystal structures of the two title piperidine derivatives show different conformations for the six-membered heterocycle. The N-substituted 4-piperidinone 1-[(1R)-2-hydroxy-1-phenylethyl]piperidin-4-one, C13H17NO2, (I), has a chair conformation ...
Nancy Romero, Sylvain Bernès, Luis F. Roa, Joel L. Terán, Dino Gnecco   +4 more
doaj   +1 more source

ANTIOXIDANT POTENTIAL OF PIPERIDINE CONTAINING COMPOUNDS-A SHORT REVIEW [PDF]

, 2018
Piperidine is a saturated heterocyclic ring, considered as a privileged scaffold in view of its role in wide range of biological activities. Piperidine is good candidate molecule for obtaining potent antioxidant agents.
K, Manjusha R, Begum, Arifa, Begum, Shaheen, K, Bharathi   +3 more
core   +1 more source

Tetrakis(μ-benzoato-κ2O:O′)bis[(piperidine-κN)rhodium]

IUCrData, 2017
The title compound, [Rh2(C7H5O2)4(C5H11N)2], an adduct of dimeric rhodium(II) benzoate with piperidine, was prepared. The complex lies across an inversion centre with the unique RhII ion in a slightly distorted octahedral coordination environment.
Detlef Selent, Hans-Joachim Drexler
doaj   +1 more source

Novel piperidine derivatives as colchicine binding site inhibitors induce apoptosis and inhibit epithelial-mesenchymal transition against prostate cancer PC3 cells

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Tubulin polymerisation inhibitors that target colchicine binding site were powerful anticancer agents. Although along the years many colchicine binding site inhibitors (CBSIs) have been reported, few piperidine derivatives were identified as CBSIs.
Dong-Jun Fu, Si-Meng Liu, Jia-Jia Yang, Jun Li   +3 more
doaj   +1 more source

PIPERIDINE OLIGOMERS AND COMBINATORIAL LIBRARIES THEREOF

, 1999
The present invention relates to piperidine oligomers, methods for the preparation of piperidine oligomers and compound libraries thereof, and the use of piperidine oligomers as drug substances.
Nielsen, John, Willert, Marianne, Carstensen, Elisabeth Vang, Bols, Michael   +3 more
core