Results 71 to 80 of about 13,079 (195)

Accelerators Derived from Piperidine

, 1934
Before the year 1913 piperidine was a compound of little more than academic interest and seldom to be found in considerable quantities outside the chemical laboratory.
M. W. Philpott
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The crystal structures of 6′-(4-chlorophenyl)- and 6′-(4-methoxyphenyl)-6a′-nitro-6a′,6b′,7′,9′,10′,12a′-hexahydro-2H,6′H,8′H-spiro[acenaphthylene-1,12′-chromeno[3,4-a]indolizin]-2-one

Acta Crystallographica Section E: Crystallographic Communications, 2019
In the title compounds, C32H25ClN2O4 (I) and C33H28N2O5 (II), the six-membered pyran and piperidine rings adopt envelope and chair conformations, respectively. The five-membered pyrrolidine rings adopt twist conformations. Compound (II) crystallizes with
S. Syed Abuthahir, M. NizamMohideen, V. Viswanathan, D. Velmurugan, J. Nagasivarao   +4 more
doaj   +1 more source

Crystal structure of (4-chlorophenyl)(4-methylpiperidin-1-yl)methanone

Acta Crystallographica Section E: Crystallographic Communications, 2020
The title compound, C13H16ClNO, contains a methylpiperidine ring in the stable chair conformation. The mean plane of the twisted piperidine ring subtends a dihedral angle of 39.89 (7)° with that of the benzene ring.
J. Srividya, D. Reuben Jonathan, B. K. Revathi, M. Divya Bharathi, G. Anbalagan   +4 more
doaj   +1 more source

Synthetic route towards potential bivalent ligands possessing opioid and D2/D3 pharmacophores [PDF]

Journal of the Serbian Chemical Society, 2019
A scalable, cost-efficient and simple synthetic pathway towards potential bivalent opioid/dopamine receptor ligands was developed and optimized. Three novel compounds that contain both opioid and dopamine pharmacophores linked by the four methylene group
Jevtić Ivana I., Penjišević Jelena Z., Ivanović Milovan D., Kostić-Rajačić Slađana V.   +3 more
doaj   +1 more source

Asymmetric piperidine synthesis [PDF]

It has been demonstrated that bakers' yeast reduction of 1-tert-butyl-2-methyl 3-oxo-piperidine-1,2-dicarboxylate gives (2R, 3S), 1-tert-butyl-2-methyl 3-hydroxy-piperidine-1,2-dicarboxylate in 80% chemical yield with >99% d.e. and >97% e.e. Also bakers'
Lewis, Neil
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Pharmacological and biochemical characteristics of blood of different groups of animals during treatment piperidine 2-(5-furan-2-yl)-4-phenyl-1,2,4-triazol-3-iltioatsetat

Zaporožskij Medicinskij Žurnal, 2013
A study of blood biochemical parameters of different groups of animals on a background of piperidine 2 - (5-furan-2-yl)-4-phenyl-1,2,4-triazol-3-iltioatsetat.
V. V. Parchenko , L. I. Parhomenko, V. Y. Izdepsky   +2 more
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Pharmacological screening of synthetic piperidine derivatives

, 2016
Submitted in complete fulfillment for the Degree of Master of Applied Sciences in Biotechnology, Durban University of Technology, Durban, South Africa, 2016.Piperidine derivatives are essential heterocyclic compounds that have beneficial roles in the ...
Naicker, Leeantha
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Synthesis and Characterization of New Functionalized Pyrimidine (Hetero)Cyclic Molecular Hybrids as Chiral Heterocyclic Amino Acid Derivatives

Molecules
Heterocyclic unnatural amino acids and their biheterocyclic derivatives represent invaluable structural scaffolds in modern medicinal chemistry and peptidomimetics due to their ability to induce conformational constraints and modulate pharmacokinetic ...
Paulina Voznikaitė, Greta Račkauskienė, Miglė Dagilienė, Vilija Kederienė, Frank A. Sløk, Algirdas Šačkus   +5 more
doaj   +1 more source

Synthesis of 2,3-(Diheterocyclyl)Propanoic Acid Esters as New Building Blocks via Complementary Meldrum’s Acid and Aza-Michael Strategies

Molecules
In this study, we developed two complementary synthetic routes to novel piperidine- and azetidine-containing 2,3-disubstituted propanoic acid derivatives as heterocyclic amino acid building blocks. The strategy employs ketone- and carboxylic acid-derived
Paulina Voznikaitė, Greta Račkauskienė, Miglė Dagilienė, Frank A. Sløk, Algirdas Šačkus   +4 more
doaj   +1 more source

Biocatalytic C–H Oxidation Meets Radical Cross-Coupling: Simplifying Complex Piperidine Synthesis [PDF]

Medicinal chemists in the modern era are targeting molecules with greater complexity to address increasingly challenging biological targets, a drive to enhance on-target specificity as well as physiochemical properties.
Hans, Renata, Benxiang, Zhang, Yu, Kawamata, phil, baran, Kenta, Yokoi, Jiayan, He, Breanna, Wixted   +6 more
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