Results 101 to 110 of about 40,681 (241)
Enantiopure Piperidines as Versatile Tools in Natural Products Synthesis
, 2004 Enantiopure Piperidines as Versatile Tools in Natural Products ...
D. Passarella, Passarella Daniele
core
Synthesis of Enantiopure Substituted Piperidines via an Aziridinium Ring Expansion
, 2016 Herein we report a novel methodology for the asymmetric synthesis of 3-substituted piperidines from readily available chiral building blocks. This method, which features a novel irreversible dihydropyrole-tetrahydropyridine ring expansion, allows the ...
Andre B. Charette (2178452) +1 more
core +2 more sources
, 2021 This thesis describes the development of synthetic routes to investigate the relative and absolute stereochemistry of a number of piperidine alkaloids isolated from Microcos Paniculata. This thesis then goes on to explore an intramolecular Diels-Alder reaction, and explores its applicability to natural product synthesis.
openaire +2 more sources
, 2018 Piperidine alkaloids are predominant in ant venom glands of S. invicta and S. saevissima. These ants are broadly sympatric in Southeastern Brazil, and potentially diagnostic compounds could assist in ant identification.
Marcela A. Botelho (4868218) +3 more
core +1 more source
, 2016 A Cu(I)-catalyzed coupling of a ω-chloro ketone, a primary amine, and an alkyne is described. This protocol allows for the synthesis of α-quaternary carbons in 2-alkynyl-substituted N-heterocycles.
Joren Van Stappen (3115848) +7 more
core +1 more source
Research progress of donepezil for treating mild to moderate Alzheimer's disease
Chinese Journal of Contemporary Neurology and Neurosurgery, 2017 Donepezil is the second generation of cholinesterase inhibitors (ChEIs), which has a good effect on mild to moderate Alzheimer's disease (AD). In recent years, there were a lot of studies on the mechanism of donepezil. This paper mainly introduces the
Xin-xin LI, Yun-yun ZHANG, Bin WANG
doaj
Organocatalytic Approach to Polysubstituted Piperidines and Tetrahydropyrans
, 2016 Polysubstituted piperidines and tetrahydropyrans are synthesized from aldehydes and two classes of trisubstituted nitroolefins via an O-TMS protected diphenylprolinol catalyzed domino Michael addition/aminalization (or acetalization) process.
Dawei Ma (275249) +2 more
core +1 more source
Stereoselective synthesis of 2,4,5-trisubstituted piperidines by carbonylene and Prins cyclisations
, 2006 Cyclisation of aldehydes 3a - e catalysed by concentrated hydrochloric acid affords predominantly the all cis 2,4,5trisubstituted piperidines 4a - e when the 2- substituent is small, while catalysis by MeAlCl2 in refluxing chloroform gives the trans ...
Snaith, John, Cariou, Claire
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Development of a [3+3] Cycloaddition Strategy toward Functionalized Piperidines
This paper describes a novel route to functionalized piperidines via a formal [3+3] cycloaddition reaction of activated aziridines and palladium−trimethylenemethane (Pd-TMM) complexes.
Hedley, Simon J. +3 more
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One-Pot Asymmetric Synthesis of Substituted Piperidines by Exocyclic Chirality Induction
, 2016 A highly efficient one-pot synthesis of substituted piperidines was developed through nitroalkene, amine, and enone condensation. The transformation was suitable for a large group of substrates, giving excellent yields and diastereoselectivity. Reactions
Novruz G. Akhmedov (1262058) +4 more
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