Results 111 to 120 of about 25,392 (338)

On the Planarity of Heterocyclic Bay‐Substituted Perylenediimides: Insight into the Fluorescent Photoinduced Electron Transfer Sensing Framework

European Journal of Organic Chemistry, EarlyView.
Near‐infrared fluorescent pH indicators based on perylenediimide were constructed in a modular receptor–spacer–fluorophore–spacer–receptor format with heterocyclic amino moieties at the bay positions. Counterintuitively, the dibrominated intermediate with two heavy atoms is more emissive than the heterocyclic compounds.
Luke Camenzuli, Davide Benedetto Tiz, Nicola’ Agius, Konrad Szaciłowski, David C. Magri   +4 more
wiley   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, EarlyView.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

Biocatalytic Preparation of Enantioenriched 3,4-Dihydroxypiperidines and Theoretical Study of Candida antarctica Lipase B Enantioselectivity [PDF]

, 2006
This work was supported by the Ministerio de Ciencia y Tecnología (PTR1995-0775-OP). L.F.S. thanks MEC for a predoctoral fellowship.
Brieva Collado, María del Rosario, Fernández Solares, Laura, Gotor Fernández, Vicente, Gotor Santamaría, Vicente Miguel, Lavandera García, Iván   +4 more
core   +2 more sources

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

Dearomatization with Axial‐to‐Central Chirality Conversion

European Journal of Organic Chemistry, EarlyView.
Atropisomers are exciting synthetic targets with unique properties, which find applications in many fields of chemistry. However, considering them as substrates is not very frequent, notably in the context of dearomatization reaction. We wish to discuss the different strategies for the dearomatization of aromatic atropisomers with axial‐to‐central ...
Morgane Mando, Clément Lemaitre, Thierry Constantieux, Xavier Bugaut   +3 more
wiley   +1 more source

[[alternative]]Designs and Syntheses of Glycosidase Inhibitors and Analogues from D-Quinic Acid [PDF]

計畫編號：NSC92-2113-M032-004研究期間：200308~200407研究經費：827,000[[sponsorship ...
施增廉
core  

A COLOR TEST FOR CERTAIN PIPERIDINE AND PYRROLIDINE ALKALOIDS [PDF]

, 1960
D. J. McCaldin
openalex   +1 more source

Hofmann Degradation of Asparagine and Glutamine as an Efficient Approach for the Synthesis of Derivatized Lysine Homologs

European Journal of Organic Chemistry, EarlyView.
A practical and scalable route to C1 and C2 lysine homologs has been developed using Hofmann degradation of N‐protected L‐asparagine and L‐glutamine as the key step. These short‐tether scaffolds enable efficient synthesis of diverse Fmoc‐protected noncanonical amino acids (ncAAs) bearing donor, acceptor, redox‐active, and fluorescent residues.
Adelaide R. Mashweu, François J. De Beer, Jolien Bertouille, Steven Ballet, Charlotte Martin, Ulrich Hennecke, Charlene Marais, Vladimir A. Azov   +7 more
wiley   +1 more source

MMP-13 Selective Isonipecotamide Alpha-sulfone Hydroxamates [PDF]

, 2010
A series of N-aryl isonipecotamide α-sulfone hydroxamate derivatives has been prepared utilizing a combination of solution-phase and resin-bound library technologies to afford compounds that are potent and highly selective for MMP ...
Becker, Daniel, DeCrescenzo, Gary A., Fletcher, Theresa R., Hockerman, Susan L., Kolodziej, Stephen A., McDonald, Joseph J., Munie, Grace E., Stehle, Nathan, Swearingen, Craig   +8 more
core  

Design and synthesis of a fragment set based on twisted bicyclic lactams

, 2018
Current fragment sets tend to be dominated by flatter molecules, and their shape diversity does not reflect that of the fragments that are theoretically possible.
Hassan, H, Marsden, S, Nelson, AS
core   +1 more source