Results 91 to 100 of about 40,681 (241)
Future Journal of Pharmaceutical Sciences, 2018 Design, synthesis and evaluation of new acetylcholinesterase inhibitors by combining carbamoylpiperidine analogs containing nipecotic acid scaffold were described.
Khairia M. Youssef +2 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2020 The tandem gold(I)-catalyzed rearrangement/Nazarov reaction of enynyl acetates in which the double bond is embedded in a piperidine ring was computationally and experimentally studied.
Giovanna Zanella +4 more
doaj +1 more source
Stereoselective synthesis of piperidines
, 2008 EDITED ABSTRACT. This thesis is divided into two parts. The first part describes the production of a small stereodiverse library of 2-substituted piperidines.
Adriaenssens, Louis
core
Opportunities and challenges for direct C–H functionalization of piperazines
Beilstein Journal of Organic Chemistry, 2016 Piperazine ranks within the top three most utilized N-heterocyclic moieties in FDA-approved small-molecule pharmaceuticals. Herein we summarize the current synthetic methods available to perform C–H functionalization on piperazines in order to lend ...
Zhishi Ye, Kristen E. Gettys, Mingji Dai
doaj +1 more source
New One-Pot Methodologies for the Modification or Synthesis of Alkaloid Scaffolds
Marine Drugs, 2010 There are several avenues by which promising bioactive natural products can be produced in sufficient quantities to enable lead optimization and medicinal chemistry studies. The total synthesis of natural products is an important, but sometimes difficult,
Amir E. Wahba, Mark T. Hamann
doaj +1 more source
Journal of the American Chemical Society, 2015 The catalytic kinetic resolution of cyclic amines with achiral N-heterocyclic carbenes (NHC) and chiral hydroxamic acids has emerged as a promising method to obtain enantioenriched amines with high selectivity factors.
Benedikt M Wanner +4 more
semanticscholar +1 more source
Diastereoselective synthesis of some novel benzopyranopyridine derivatives
Beilstein Journal of Organic Chemistry, 2006 BackgroundThe formation of novel N-substituted-1,2,3,4-tetrahydro[1,3]-dioxolo-[6,7]-5H-[1]benzopyrano [3,4-c]pyridines were observed unexpectedly during the acid-mediated ketal removal of ethylenedioxy ketal protected 4-piperidones.
Pradeep K. Mohakhud +6 more
doaj +1 more source
Synthesis of substituted indano[2,1-c]piperidines
, 2020 Substituted indano[2,1-c]piperidines were obtained by selective hydrogenation over Re2S7 and also by reduction with sodium in alcohol of 3-methyl-2-azafluorene and its derivatives. The geometrical isomers of the products were isolated and characterized. ©
Urbina G.A. +3 more
core +1 more source
The Synthesis and Biological Activity of 1-Alkyl-4-(3-azacyclobenzoyl)-5-hydroxypyrazole Herbicides
CHIMIA, 2003 The benzoylpyrazoles belong to a class of herbicides that inhibit the enzyme 4-hydroxy-phenylpyruvate dioxygenase (HPPD). This mode of action is characterized by bleaching due to the disruption of plastoquinone and ?-tocopherol biosynthesis ...
Zoltan Benko +8 more
doaj +1 more source
A Single Step Approach to Piperidines via Ni-Catalyzed β-Carbon Elimination
, 2016 An easy and expeditious route to substituted piperidines is described. A Ni-phosphine complex was used as catalyst for [4 + 2] cycloaddition of 3-azetidinone and alkynes.
Janis Louie (1348188) +1 more
core +2 more sources