Results 241 to 250 of about 40,506 (345)

Complex‐mediated nucleophilic aromatic substitution with aryl nitriles to realize intramolecular flapping‐restricted D‐A AIEgens for bioimaging

open access: yesSmart Molecules, EarlyView.
In this work, we developed a complex‐mediated nucleophilic aromatic substitution which can generate rich D‐A AIEgens under a facile condition. The AIE mechanism of such AIEgens was unveiled and their application towards fatty liver imaging was exhibited. Abstract Donor‐acceptor (D‐A) compounds are particularly important in optoelectronic and biological
Feng Liu   +12 more
wiley   +1 more source

Machine Learning‐Assisted Prediction and Generation of Antimicrobial Peptides

open access: yesSmall Science, EarlyView.
A machine learning‐based in silico predictive and generative model is developed to engineer highly effective antimicrobial peptides (AMPs) for combating multidrug‐resistant pathogens. An iterative algorithm involving peptide generation, scoring, and motif identification produces AMPs with high theoretical scores.
Sukhvir Kaur Bhangu   +6 more
wiley   +1 more source

Kartogenin‐Loaded Aminated Hollow Mesoporous Prussian Blue Nanozyme‐Reinforced Hydrogel Remodels the Senescent Microenvironment via Reactive Oxygen Species Scavenging and Stimulator of Interferon Genes Inhibition to Promote Cartilage Regeneration

open access: yesSmall Structures, EarlyView.
This study successfully develops an injectable, dual‐function nanocomposite hydrogel comprising kartogenin‐loaded aminated hollow mesoporous Prussian blue (NH2‐HMPB) nanozyme (termed NH@K nanozyme) and hyaluronic acid methacrylate (HAMA). NH@K nanozyme rejuvenates the senescent microenvironment by scavenging reactive oxygen species and inhibiting ...
Shu‐Hang He   +10 more
wiley   +1 more source

Perovskite‐Inspired Materials (PIMs): Exploring Their Potential for Photovoltaic Applications

open access: yesSusMat, EarlyView.
Perovskite‐inspired materials (PIMs) have gained significant attention as alternatives to traditional lead‐based perovskites, offering the ability to overcome challenges related to lead toxicity and instability while maintaining the favorable optoelectronic properties of perovskites.
Dong‐Am Park, Nam‐Gyu Park
wiley   +1 more source

Structural Screening of Short Peptide Amphiphiles with Autocatalytic Self‐Replication

open access: yesChemSystemsChem, EarlyView.
Two reactive precursors generate peptide amphiphile products that can self‐assemble into micelles. These micelles can catalyse precursor reactivity, triggering autocatalytic self‐replication, whereby the product of the reaction catalyses the formation of molecular copies of itself.
Ion Turcan, Ignacio Insua
wiley   +1 more source

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