Results 261 to 270 of about 24,641 (321)

Syntheses of N-(Chlorobenzoylaminoalkyl)piperidines and N-(Chlorothiobenzoylaminoalkyl)piperidines

Nippon kagaku zassi, 1969
Kakuzo Isagawa, Takuji Hirose, Yasaburo Fushizaki   +2 more
openaire   +2 more sources

Frame‐Shifted Synthesis of Oligoheterocycles as a Platform for Molecular Design

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Modern chemistry seeks to turn the simple raw materials into complex molecules that matter in health, agriculture, and technology. Among these, oligoheterocycles stand out for their versatility, yet they are most often built by cross‐coupling reactions that often rely on expensive metal catalysts.
Kane A. C. Bastick, Caleb E. Griesbach, Ben Zhen Huang, Morgan J. Cordell, Yang (Daniel) Ou, Alán Aspuru‐Guzik, Andrei K. Yudin   +6 more
wiley   +2 more sources

Emergence of PALB2 Reversion Mutations as a Mechanism of Resistance to Niraparib in Breast Cancer: A Case Report. [PDF]

Cancer Sci
Kawamura M, Tada H, Shirota H, Dobashi M, Takenaga N, Yasojima H, Harada-Shoji N, Komine K, Nakamura K, Miyashita M, Kawakami H.   +10 more
europepmc   +1 more source

Electrochemical Hydrogenation of Aza-Arenes Using H₂O as H Source. [PDF]

J Am Chem Soc
Dutta S, Narobe R, Waldvogel SR.
europepmc   +1 more source

Stereocontrolled synthesis of 3-hydroxy-2-piperidinone carboxamides by catalytic ring-opening aminolysis of bridged <i>δ</i>-lactam-γ-lactones. [PDF]

RSC Adv
Beng TK, Curry K, Gitonga A, Yu K, Edwards S.   +4 more
europepmc   +1 more source

The effect of fire ant (Hymenoptera: Formicidae) venom on ecologically relevant bacteria. [PDF]

J Econ Entomol
Morris A, Vander Meer RK, Pereira R, Baldwin R, Chinta S.   +4 more
europepmc   +1 more source

Novel Potent and Selective Dopamine D4 Receptor Piperidine Antagonists as Potential Alternatives for the Treatment of Glioblastoma. [PDF]

Pharmaceuticals (Basel)
Matteucci F, Pavletić P, Bonifazi A, Garland R, Yano H, Amantini C, Zeppa L, Sabato E, Vistoli G, Mammoli V, Cappellacci L, Del Bello F, Giorgioni G, Petrelli R, Piergentili A, Quaglia W, Piergentili A.   +16 more
europepmc   +1 more source

Efficacy and Safety of Tofacitinib in Palmoplantar Pustulosis: A Retrospective Study. [PDF]

Acta Derm Venereol
Lyu S, Xue X, Wang N, Liu H, Zhang F.
europepmc   +1 more source

Combining Aggregate Data and Individual Patient Data in Model-Based Meta-Analysis: An Illustrative Case Study of Tofacitinib in Rheumatoid Arthritis Patients. [PDF]

CPT Pharmacometrics Syst Pharmacol
Pham TN, Largajolli A, Sardu ML, Maringwa J, Zierhut ML, Cheung SYA.   +5 more
europepmc   +1 more source

Simultaneous Grafting of 3,4,5‐Trihydroxypiperidine Iminosugars Onto Multivalent Scaffolds via Double Reductive Amination Provides New GCase Inhibitors

Chemistry – A European Journal, Volume 32, Issue 2, 9 January 2026.
A small set of low‐valency multivalent 3,4,5‐trihydroxypiperidines was prepared through double reductive amination (DRA) of a sugar‐derived dialdehyde. Among them, trivalent derivative 37 emerged as a potent β‐glucocerebrosidase (GCase) inhibitor displaying an unexpected mixed‐type kinetic profile. The integration of kinetic analysis, NMR, docking, and
Maria Giulia Davighi, Francesca Clemente, Alessio Morano, Francesca Mangiavacchi, Francesca Cardona, Andrea Goti, Paolo Paoli, Amelia Morrone, Ferran Nieto‐Fabregat, Roberta Marchetti, Camilla Matassini   +10 more
wiley   +1 more source