Results 91 to 100 of about 5,094 (194)
Synthesis and late-stage functionalization of complex molecules through C-H fluorination and nucleophilic aromatic substitution. [PDF]
, 2014 We report the late-stage functionalization of multisubstituted pyridines and diazines at the position α to nitrogen. By this process, a series of functional groups and substituents bound to the ring through nitrogen, oxygen, sulfur, or carbon are ...
Fier, Patrick S, Hartwig, John F
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Journal of Pharmacological Sciences, 2016 The present study investigated pharmacological characterizations of muscarinic acetylcholine receptor (AChR) subtypes involving ACh-induced endothelium-independent vasodilatation in rat mesenteric arteries.
Panot Tangsucharit +6 more
doaj +1 more source
, 1988 Updates on research conducted by the Boston University School of ...
Boston University School of Medicine
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Carbachol and bradykinin elevate cyclic AMP and rapidly deplete ATP in cultured rat sympathetic neurons [PDF]
, 1991 The agonists carbachol (CCh) and bradykinin (BK) and 54 mM KCl (high K+) were among the most potent stimulants of cyclic AMP (cAMP) production in cultured rat sympathetic neurons, measured with the use of a high-fidelity assay developed for small samples.
Murrell, R D +2 more
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International Journal of Endocrinology, 2017 Muscarinic receptors types 1 (m1AChR) and 2 (m2AChR) in the preoptic and anterior hypothalamus areas (POA-AHA) were counted, and the effects of blocking these receptors on spontaneous ovulation were analysed throughout the rat oestrous cycle.
Yadira L. López-Ramírez +8 more
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Journal of Pharmacological Sciences, 2007 The inotropic response to muscarinic receptor stimulation of isolated chick ventricular myocardium was examined at various developmental stages, and the receptor subtype involved was pharmacologically characterized.
Hideaki Nouchi +7 more
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Peripheral refraction in myopic patients after Orthokeratology [PDF]
, 2010 Purpose: The purpose of this study was to characterize the central and peripheral refraction across the horizontal meridian of the visual field before and after myopic corneal refractive therapy (CRT) with contact lenses.
González-Méijome, José Manuel +4 more
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Calcium Mobilization by Activation of M3/M5 Muscarinic Receptors in the Human Retinoblastoma
Journal of Pharmacological Sciences, 2007 Activation of muscarinic acetylcholine receptors (mAChR) is one of the most important signal transduction pathways in the human body. In this study, we investigated the role of mAChR activation in relation to its subtypes in human retinoblastoma cell ...
Dae-Ran Kim +8 more
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The Camerino symposium series (1978–2013): a privileged observatory of receptorology development [PDF]
, 2013 The organizers of the Camerino Receptor Symposia survey the development of receptorology. They trace the course from the first Symposium in 1978, which laid the foundation for Pirenzepine, the first selective muscarinic antagonist, to the 2010 Symposium,
Mario Giannella, Piero Angeli
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Identification of M1 muscarinic receptors in pulmonary sympathetic nerves in the guinea‐pig by use of pirenzepine [PDF]
, 1989 Jennifer Maclagan +2 more
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