Results 1 to 10 of about 607 (146)

Correction: Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones

Organic & Biomolecular Chemistry, 2017
Correction for ‘Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones’ by Hasan Mtiraoui, et al. , Org. Biomol. Chem. , 2017, 15 , 3060–3068.
Hasan, Mtiraoui, Kevin, Renault, Morgane, Sanselme, Moncef, Msaddek, Pierre-Yves, Renard, Cyrille, Sabot   +5 more
openaire   +4 more sources

Mannich-Type Condensation and Domino Quinazolinone-Amidine Rearrangement Affords Ring-Fused Mackinazolinones with Anti-Amoebic Activity. [PDF]

Adv Synth Catal, 2023
Abstract A three‐step synthesis of anti‐amoebic, ring‐fused mackinazolinones has been developed. A Mannich‐type reaction between quinazolin‐4‐ones and N‐Cbz propanal in the presence of AgOTf afforded quinazolinones (19–94% isolated yield) bearing a newly formed heterocycle with an alkylamine appendage that, upon N‐Cbz deprotection and basification ...
Lish MS, Milanes JE, Sanders KM, Guzei IA, Morris JC, Golden JE.   +5 more
europepmc   +2 more sources

Piperazinobenzodiazepinones: New Encephalitic Alphavirus Inhibitors via Ring Expansion of 2-Dichloromethylquinazolinones. [PDF]

ACS Med Chem Lett, 2022
Venezuelan and eastern equine encephalitis viruses are disease-causing, neuropathic pathogens with no approved treatment options in humans. While expanding the pharmacophoric model of antialphaviral amidines prepared via a quinazolinone rearrangement, we
Ryan MC, Kim E, Cao X, Reichard W, Ogorek TJ, Das P, Jonsson CB, Baudry J, Chung D, Golden JE.   +9 more
europepmc   +2 more sources

(4Z)-1-Benzyl (1,3-Dibenzyl)-4-(2-oxopropylidene)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one

Molbank, 2006
n ...
Ould Mohamed Sidya Mohamed Said, Bouhfid Rachid, Nicolas Joly, Vincent Lequart, Patrick Martin, M. Massoui, El Mokhtar Essassi   +6 more
doaj   +1 more source

Steric control of reactivity: formation of oximes, benzodiazepinone N-oxides and isoxazoloquinolinones [PDF]

Journal of the Chemical Society, Perkin Transactions 2, 1998
Reaction of the alkenyl carbonyl compounds 1 with hydroxylamine can lead to the formation of the oximes 2, the benzodiazepinone N-oxides 3 or the isoxazoloquinolinones 5. The product(s) of reaction are shown to depend on the electronic nature of the terminal olefinic substituent R-3 and the space filling capacity of the substituents R-1, R-2 and R-4 ...
Heaney, Frances, Bourke, Sharon, Cunningham, Desmond, McArdle, Patrick   +3 more
openaire   +3 more sources

Benzodiazepinones [PDF]

Reactions Weekly, 2022
openaire   +1 more source

Syntheses of the Novel Furo [3, 4-b] [1, 5] benzodiazepinone and Pyrrolo [3, 4-b] [1, 5] benzodiazepinone Systems

CHEMICAL & PHARMACEUTICAL BULLETIN, 1984
Synthese par action de l'o-phenylenediamine sur l'acide dimethyl-5,5 tetronique et l'acide dimethyl-5,5 ...
MATSUO, KEIZO, TANAKA, KUNIYOSHI
openaire   +2 more sources

A comprehensive evaluation between dexmedetomidine and midazolam for intraoperative sedation in the elderly: protocol for a systematic review and meta-analysis of randomized controlled trials. [PDF]

Syst Rev, 2022
Huang C, Li Z, Long Y, Li D, Huang M, Ding B, Zhu W.   +6 more
europepmc   +1 more source

New Class of Benzodiazepinone Derivatives as Pro-Death Agents Targeting BIR Domains in Cancer Cells. [PDF]

Molecules, 2023
Fiore M, Mosconi M, Bonì F, Parodi A, Salis A, Tasso B, Mastrangelo E, Millo E, Cossu F.   +8 more
europepmc   +1 more source

Structure-activity relationship of BMS906024 derivatives for Cryptosporidium parvum growth inhibition. [PDF]

Bioorg Med Chem Lett, 2023
Lee S, Love MS, Modukuri R, Chatterjee AK, Huerta L, Lawson AP, McNamara CW, Mead JR, Hedstrom L, Cuny GD.   +9 more
europepmc   +1 more source