ChemInform Abstract: Dihydro‐1,4‐benzodiazepinones and ‐thiones
ChemInform, 1991 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
R. I. FRYER, A. WALSER
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Piperazinobenzodiazepinones: New Encephalitic Alphavirus Inhibitors via Ring Expansion of 2-Dichloromethylquinazolinones. [PDF]
ACS Med Chem Lett, 2022 Venezuelan and eastern equine encephalitis viruses are disease-causing, neuropathic pathogens with no approved treatment options in humans. While expanding the pharmacophoric model of antialphaviral amidines prepared via a quinazolinone rearrangement, we
Ryan MC +9 more
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Variable temperature n.m.r behaviour of 1,5-benzodiazepinones and 1,5-benzodiazepinthiones
Organic Magnetic Resonance, 1976 The n.m.r. variable temperature behaviour of the 7-membered ring in 1,3-dihydro-2H-1,5-benzodiazepin-2-one derivatives and in the corresponding 2-thiones has been investigated. The results indicate that the ring inversion barrier is higher in the thiones
A. TAJANA +4 more
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Benzodiazepinone Derivatives as CRTH2 Antagonists. [PDF]
ACS Med Chem Lett, 2011 Multiple CRTH2 antagonists are currently evaluated in human clinical trials for asthma and chronic obstructive pulmonary disease (COPD). During our lead optimization for CRTH2 antagonists, an observation of an intramolecular hydrogen bond in ortho-phenylsulfonamido benzophenone derivatives led to the design and synthesis of conformationally constrained
Liu JJ, Cheng AC, Tang HL, Medina JC.
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Opioid analgesics/benzodiazepinones/tetrahydrocannabinol overdose
Reactions Weekly, 2018 core +2 more sources
Synthesis of Tetrazolo-Fused Benzodiazepines and Benzodiazepinones by a Two-Step Protocol Using an Ugi-Azide Reaction for Initial Diversity Generation. [PDF]
Tetrahedron, 2012 Gunawan S +7 more
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(4Z)-1-Propargyl(1,3-Dipropargyl)-4-(2-oxopropylidene)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
Molbank, 2006 n ...
Ould Mohamed Sidya Mohamed Said +6 more
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(4Z)-1-Benzyl (1,3-Dibenzyl)-4-(2-oxopropylidene)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
Molbank, 2006 n ...
Ould Mohamed Sidya Mohamed Said +6 more
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Advanced Science, Volume 7, Issue 22, November 18, 2020., 2020 A single‐stranded DNA‐encoded chemical library (DEL) of 366 600 compounds, based on a stereoisomeric scaffold and on a single‐stranded DNA format, allows the isolation of ligands against multiple protein targets. The library can also be hybridized to a complementary DNA strand equipped with a protein binder, in order to generate affinity‐matured ...
Gabriele Bassi +15 more
wiley +1 more source