Results 11 to 20 of about 520 (121)
Synthesis of tetrazolo-fused benzodiazepines and benzodiazepinones by a two-step protocol using an Ugi-azide reaction for initial diversity generation [PDF]
Tetrahedron, 2012 Muhammad Ayaz, , Brendan Frett
exaly +2 more sources
SYNTHESIS OF NEW FUSED BENZOPYRANO-BENZODIAZEPINONES
Heterocyclic Communications, 2002 Zine Mighri, Marie-Therese Martin
exaly +2 more sources
Challenging Atroposelective C–H Arylation
SynOpen, 2020 Atropisomeric molecules are privileged scaffolds, not only as ligands for asymmetric synthesis, but also as biologically active products and advanced materials.
Joanna Wencel-Delord +1 more
doaj +1 more source
(4Z)-1-Propargyl(1,3-Dipropargyl)-4-(2-oxopropylidene)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
Molbank, 2006 n ...
Ould Mohamed Sidya Mohamed Said +6 more
doaj +1 more source
(4Z)-1-Benzyl (1,3-Dibenzyl)-4-(2-oxopropylidene)-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
Molbank, 2006 n ...
Ould Mohamed Sidya Mohamed Said +6 more
doaj +1 more source
Advanced Science, Volume 7, Issue 22, November 18, 2020., 2020 A single‐stranded DNA‐encoded chemical library (DEL) of 366 600 compounds, based on a stereoisomeric scaffold and on a single‐stranded DNA format, allows the isolation of ligands against multiple protein targets. The library can also be hybridized to a complementary DNA strand equipped with a protein binder, in order to generate affinity‐matured ...
Gabriele Bassi +15 more
wiley +1 more source
Rottlerin: Structure Modifications and KCNQ1/KCNE1 Ion Channel Activity
ChemMedChem, Volume 15, Issue 12, Page 1078-1088, June 17, 2020., 2020 The polyphenolic natural product rottlerin, isolated from Kamala powder, has been used for centuries in traditional Indian medicine. Among other biological effects, rottlerin has been shown to activate KCNQ1 potassium channels. Rottlerin analogues were synthesized and evaluated electrophysiologically in X. laevis oocytes.
Marco Lübke +10 more
wiley +1 more source
Role of Endoplasmic Reticulum Stress in Atherosclerosis and Diabetic Macrovascular Complications
BioMed Research International, Volume 2014, Issue 1, 2014., 2014 Age‐related changes in endoplasmic reticulum (ER) are associated with stress of this cell organelle. Unfolded protein response (UPR) is a normal physiological reaction of a cell in order to prevent accumulation of unfolded and misfolded proteins in the ER and improve the normal ER function.
Dmitry A. Chistiakov +4 more
wiley +1 more source
International Journal of Photoenergy, Volume 3, Issue 4, Page 205-211, 2001., 2001 The photostability of selected drug molecules, including furosemide, prochlorperazine, diclofenac, piroxicam, midazolam and nifedipine was studied, the kinetics of photodegradation, identification of the photodegradants investigated and mechanisms of photodegradation proposed.
B. D. Glass +8 more
wiley +1 more source
Electrochemical Intramolecular Aminobromination of Alkenes
European Journal of Organic Chemistry, Volume 29, Issue 2, January 16, 2026.A versatile electrochemical method for the intramolecular aminobromination of alkenes has been developed. The method provides access to five‐, six‐, and seven‐membered heterocycles by exploiting tetrabutylammonium bromide as an electrolyte and bromine source.
Sara Colombo +9 more
wiley +1 more source