Results 81 to 90 of about 5,030 (261)

Influence of Overnight Orthokeratology on Axial Elongation in Childhood Myopia [PDF]

open access: yes, 2011
Purpose. This prospective study was conducted to assess the influence of overnight orthokeratology (OK) on axial elongation in children, with those wearing spectacles as controls.Methods.
Hiraoka Takahiro   +5 more
core   +1 more source

Poly (ADP-Ribose) Polymerase-1 (PARP1) Deficiency and Pharmacological Inhibition by Pirenzepine Protects From Cisplatin-Induced Ototoxicity Without Affecting Antitumor Efficacy

open access: yesFrontiers in Cellular Neuroscience, 2019
Cisplatin remains an indispensable drug for the systemic treatment of many solid tumors. However, a major dose-limiting side-effect is ototoxicity. In some scenarios, such as treatment of germ cell tumors or adjuvant therapy of non-small cell lung cancer,
Anke Tropitzsch   +7 more
doaj   +1 more source

The Impact of Removal of Ovarian Hormones on Cholinergic Muscarinic Receptors: Examining Prepulse Inhibition and Receptor Binding

open access: yesBrain Sciences, 2020
Ovarian hormones, such as estrogens and progesterone, are known to exert beneficial effects on cognition and some psychiatric disorders. The basis of these effects is not fully understood, but may involve altered cholinergic neurotransmission. This study
Sarah S. Ch’ng   +9 more
doaj   +1 more source

The novel protein kinase C epsilon isoform modulates acetylcholine release in the rat neuromuscular junction [PDF]

open access: yes, 2015
BACKGROUND: Various protein kinase C (PKC) isoforms contribute to the phosphorylating activity that modulates neurotransmitter release. In previous studies we showed that nPKCε is confined in the presynaptic site of the neuromuscular junction and its ...
Anna Simon   +9 more
core   +1 more source

Duration judgements in patients with schizophrenia [PDF]

open access: yes, 2003
Background. The ability to encode time cues underlies many cognitive processes. In the light of schizophrenic patients' compromised cognitive abilities in a variety of domains, it is noteworthy that there are numerous reports of these patients displaying
Brown, G. D. A. (Gordon D. A.)   +5 more
core   +1 more source

The Lower Urinary Tract Science Group Abstracts—ICI‐RS 2024

open access: yes
Neurourology and Urodynamics, Volume 44, Issue 3, Page 691-697, March 2025.
Christopher H. Fry   +10 more
wiley   +1 more source

Behavioral effects of Bj-PRO-7a, a proline-rich oligopeptide from Bothrops jararaca venom [PDF]

open access: yesBrazilian Journal of Medical and Biological Research
The heptapeptide Bj-PRO-7a, isolated and identified from Bothrops jararaca (Bj) venom, produces antihypertensive and other cardiovascular effects that are independent on angiotensin converting enzyme inhibition, possibly relying on cholinergic muscarinic
L.C. Turones   +11 more
doaj   +2 more sources

Identification of novel therapeutics for complex diseases from genome-wide association data [PDF]

open access: yes, 2014
Background: Human genome sequencing has enabled the association of phenotypes with genetic loci, but our ability to effectively translate this data to the clinic has not kept pace.
Ballouz, S.   +6 more
core   +1 more source

Effects of AF-DX116 and Other Muscarinic Receptor Antagonists on Orthostatic Hypotension in Autonomic Imbalanced (SART-Stressed) Rats

open access: yesJournal of Pharmacological Sciences, 2005
SART (specific alternation of rhythm in temperature)-stressed rats are an animal model of autonomic imbalance created by exposing animals to repeated cold stress. The SART-stressed rats have been shown to easily develop orthostatic hypotension (OH).
Taeko Hata   +2 more
doaj   +1 more source

Novel aspects of cholinergic regulation of colonic ion transport [PDF]

open access: yes, 2015
Nicotinic receptors are not only expressed by excitable tissues, but have been identified in various epithelia. One aim of this study was to investigate the expression of nicotinic receptors and their involvement in the regulation of ion transport across
Bader, Sandra, Diener, Martin
core   +1 more source

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