Results 81 to 90 of about 2,163 (132)
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Inhibition of carbonic anhydrase by pirenzepine.
International journal of clinical pharmacology, therapy, and toxicology, 1981Previous work of the authors established a parallelism between gastric mucosa carbonic anhydrase (CA) activity and the values of acid secretion. It was shown that histamine (Ht) is a physiological activator of CA, and that there could be histaminic H2 receptors located on the molecule of CA. Pirenzepine (GZ) is a drug recently introduced in the therapy
I, Puşcaş +3 more
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Pirenzepine for clozapine-induced hypersalivation
The Lancet, 1995J, Fritze, T, Elliger
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The effect of pirenzepine on esophageal motility.
Scandinavian journal of gastroenterology. Supplement, 1982The effect of pirenzepine on esophageal motility was studied in ten healthy volunteers by manometry. Pirenzepine reduces lower esophageal sphincter pressure (LESP), amplitude, and duration of esophageal contractions, but it increases velocity of propagation of esophageal contractions.
E, Erckenbrecht +4 more
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Pirenzepine in the treatment of duodenal ulcer.
Scandinavian journal of gastroenterology. Supplement, 1980The effectiveness and safety of pirenzepine (PRZ) at 150 mg daily in the treatment of active duodenal ulcer was studied in an open pilot clinical trial followed by a double-blind trial against placebo. The open pilot study showed that pirenzepine was well tolerated and promoted ulcer healing in the 45% of patients within 2 weeks of treatment and in 90%
N, D'Imperio +4 more
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Acute effects of pirenzepin on bronchospasm.
International journal of clinical pharmacology, therapy, and toxicology, 1987The response to pirenzepin, a new acetylcholine receptor blocking agent, was assessed and compared to placebo in patients with reversible bronchoconstriction. A single intravenous injection of 20 mg of pirenzepin induced a significant reduction of airway resistance compared to placebo (p less than 0.05). The anticholinergic substance pirenzepin appears
K, Sertl +5 more
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The effect of pirenzepine on spatial learning in the Morris Water Maze
Pharmacology Biochemistry and Behavior, 1988A J Hunter, A J Hunter
exaly

