Results 61 to 70 of about 5,030 (261)

Activations of muscarinic M receptors in the anterior cingulate cortex contribute to the antinociceptive effect via GABAergic transmission

open access: yesMolecular Pain, 2017
Background Cholinergic systems regulate the synaptic transmission resulting in the contribution of the nociceptive behaviors. Anterior cingulate cortex is a key cortical area to play roles in nociception and chronic pain.
Kohei Koga   +8 more
doaj   +1 more source

Acetylcholine regulates ghrelin secretion in humans [PDF]

open access: yes, 2004
Ghrelin secretion has been reportedly increased by fasting and energy restriction but decreased by food intake, glucose, insulin, and somatostatin. However, its regulation is still far from clarified.
Aart Jan van der Lely   +60 more
core   +2 more sources

Powikłania ze strony przewodu pokarmowego w trakcie leczenia klozapiną

open access: yesPsychiatria i Psychologia Kliniczna, 2015
Klozapina jest ostateczną opcją terapeutyczną w przypadku pacjentów ze schizofrenią oporną na leczenie. Podczas terapii często występują działania niepożądane ze strony przewodu pokarmowego: ślinotok, zaparcia, niedrożność jelit, niewydolność wątroby ...
Adam Wysokiński
doaj   +1 more source

Synthesis and late-stage functionalization of complex molecules through C-H fluorination and nucleophilic aromatic substitution. [PDF]

open access: yes, 2014
We report the late-stage functionalization of multisubstituted pyridines and diazines at the position α to nitrogen. By this process, a series of functional groups and substituents bound to the ring through nitrogen, oxygen, sulfur, or carbon are ...
Fier, Patrick S, Hartwig, John F
core   +3 more sources

A molecular basis for selective antagonist destabilization of dopamine D3 receptor quaternary organization [PDF]

open access: yes, 2017
The dopamine D3 receptor (D3R) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that a ...
Caltabiano, Gianluigi   +6 more
core   +2 more sources

Dealing With Clozapine-Induced Sialorrhea

open access: yesEuropean Psychiatry, 2022
Introduction Clozapine is the first atypical antipsychotic. It is used in refractory schizophrenia. It has a heavy side effect burden, including weight gain, dizziness, blurred vision, and sialorrhea.
J. Sá Couto   +4 more
doaj   +1 more source

Homecare amyotrophic lateral sclerosis (ALS): A multidisciplinary, home‐based model of care for patients with ALS and their caregivers

open access: yesMuscle &Nerve, Volume 70, Issue 5, Page 937-943, November 2024.
Abstract Introduction/Aims Multidisciplinary care for patients with amyotrophic lateral sclerosis (ALS) is recommended in international guidelines, but reaches its limits when immobility increases. This pilot project addresses this gap by delivering home‐based, specialized, multiprofessional support to ALS patients who are not able to attend outpatient
Sarah Kristina Bublitz   +5 more
wiley   +1 more source

Peripheral refraction in myopic patients after Orthokeratology [PDF]

open access: yes, 2010
Purpose: The purpose of this study was to characterize the central and peripheral refraction across the horizontal meridian of the visual field before and after myopic corneal refractive therapy (CRT) with contact lenses.
González-Méijome, José Manuel   +4 more
core   +1 more source

Neural control of tumor immunity

open access: yesThe FEBS Journal, Volume 291, Issue 21, Page 4670-4679, November 2024.
Cancers are innervated by sensory, sympathetic and/or parasympathetic nerves. Interactions between these nerves, cancer cells as well as immune cells regulate overall tumor progression. While this indicates that the peripheral nervous system could be a potential target for promoting anti‐tumor immune responses, the precise mechanisms underlying nerve ...
Burak Kizil   +2 more
wiley   +1 more source

In vitro release of two anti-muscarinic drugs from soft contact lenses

open access: yesClinical Ophthalmology, 2017
Alex Hui,1 Magdalena Bajgrowicz-Cieslak,2 Chau-Minh Phan,3 Lyndon Jones3 1School of Optometry and Vision Science, UNSW Sydney, Sydney, NSW, Australia; 2Department of Mechanics, Material Science and Engineering, Wroclaw University of Technology, Wroclaw,
Hui A   +3 more
doaj  

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