Results 61 to 70 of about 5,030 (261)
Background Cholinergic systems regulate the synaptic transmission resulting in the contribution of the nociceptive behaviors. Anterior cingulate cortex is a key cortical area to play roles in nociception and chronic pain.
Kohei Koga +8 more
doaj +1 more source
Acetylcholine regulates ghrelin secretion in humans [PDF]
Ghrelin secretion has been reportedly increased by fasting and energy restriction but decreased by food intake, glucose, insulin, and somatostatin. However, its regulation is still far from clarified.
Aart Jan van der Lely +60 more
core +2 more sources
Powikłania ze strony przewodu pokarmowego w trakcie leczenia klozapiną
Klozapina jest ostateczną opcją terapeutyczną w przypadku pacjentów ze schizofrenią oporną na leczenie. Podczas terapii często występują działania niepożądane ze strony przewodu pokarmowego: ślinotok, zaparcia, niedrożność jelit, niewydolność wątroby ...
Adam Wysokiński
doaj +1 more source
Synthesis and late-stage functionalization of complex molecules through C-H fluorination and nucleophilic aromatic substitution. [PDF]
We report the late-stage functionalization of multisubstituted pyridines and diazines at the position α to nitrogen. By this process, a series of functional groups and substituents bound to the ring through nitrogen, oxygen, sulfur, or carbon are ...
Fier, Patrick S, Hartwig, John F
core +3 more sources
A molecular basis for selective antagonist destabilization of dopamine D3 receptor quaternary organization [PDF]
The dopamine D3 receptor (D3R) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that a ...
Caltabiano, Gianluigi +6 more
core +2 more sources
Dealing With Clozapine-Induced Sialorrhea
Introduction Clozapine is the first atypical antipsychotic. It is used in refractory schizophrenia. It has a heavy side effect burden, including weight gain, dizziness, blurred vision, and sialorrhea.
J. Sá Couto +4 more
doaj +1 more source
Abstract Introduction/Aims Multidisciplinary care for patients with amyotrophic lateral sclerosis (ALS) is recommended in international guidelines, but reaches its limits when immobility increases. This pilot project addresses this gap by delivering home‐based, specialized, multiprofessional support to ALS patients who are not able to attend outpatient
Sarah Kristina Bublitz +5 more
wiley +1 more source
Peripheral refraction in myopic patients after Orthokeratology [PDF]
Purpose: The purpose of this study was to characterize the central and peripheral refraction across the horizontal meridian of the visual field before and after myopic corneal refractive therapy (CRT) with contact lenses.
González-Méijome, José Manuel +4 more
core +1 more source
Neural control of tumor immunity
Cancers are innervated by sensory, sympathetic and/or parasympathetic nerves. Interactions between these nerves, cancer cells as well as immune cells regulate overall tumor progression. While this indicates that the peripheral nervous system could be a potential target for promoting anti‐tumor immune responses, the precise mechanisms underlying nerve ...
Burak Kizil +2 more
wiley +1 more source
In vitro release of two anti-muscarinic drugs from soft contact lenses
Alex Hui,1 Magdalena Bajgrowicz-Cieslak,2 Chau-Minh Phan,3 Lyndon Jones3 1School of Optometry and Vision Science, UNSW Sydney, Sydney, NSW, Australia; 2Department of Mechanics, Material Science and Engineering, Wroclaw University of Technology, Wroclaw,
Hui A +3 more
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