Results 91 to 100 of about 2,988 (212)
, 1989 Both classical (atropine) and non-traditional (pirenzepine, metacine) antagonists of the muscarinic cholinoreceptors induce, rather than block, an intense and prolonged salivary response in chronically denervated human parotid glands and thus are capable
I M Kiselman, S L Levin
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Calcium Mobilization by Activation of M3/M5 Muscarinic Receptors in the Human Retinoblastoma
Journal of Pharmacological Sciences, 2007 Activation of muscarinic acetylcholine receptors (mAChR) is one of the most important signal transduction pathways in the human body. In this study, we investigated the role of mAChR activation in relation to its subtypes in human retinoblastoma cell ...
Dae-Ran Kim +8 more
doaj +1 more source
, 1985 A high-performance liquid chromatographic procedure for the determination of pirenzepine dihydrochloride as a bulk material and in its tablet dosage form (GastrozepinR) is presented.
Mohammad A. Abounassif +1 more
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Effect of centrally administered atropine and pirenzepine on radial arm maze performance in the rat
, 1991 The effect of two anticholinergic drugs administered intracerebroventricularly on acquisition of an 8-arm radial maze task was examined in the rat.
S. Gianola +6 more
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, 1989 The effects of pirenzepine on gastric and duodenal ulceration and barrier mucus levels, as well as on changes of superior mesenteric artery diameter caused by cysteamine, were investigated in rats and compared with those of atropine.
Chiavarini M. +11 more
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Design and Evaluation of Microspheres Loaded With Pirenzepine
, 2018 The current objective of the investigation was to fabricate Pirenzepine loaded microspheres for the treatment of gastritis delivered through oral route. The microspheres were prepared by ionotropic gelation technique using sodium as alginate polymer and ...
A. Aparna +2 more
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British Journal of Anaesthesia, 1998 We conducted a two-part controlled study to evaluate the efficacy of preoperative oral pirenzepine (muscarinic receptor antagonist known to inhibit gastric secretion), ranitidine, and the combination pirenzepine-ranitidine in controlling gastric fluid pH and volume in 210 ASA I children, aged 2-14 yr, undergoing elective surgery.
N, Maekawa +4 more
openaire +2 more sources
A 1H nmr study of the amide-bond conformational equilibrium in pirenzepine
, 1984 The hindered rotation about the exocyclic amide bond of pirenzepine has been studied using 1H nuclear magnetic resonance spectroscopy. The ratios of the two slowly interconverting conformations (1:1·76 at 2 °C and 1:2·37 at 30 °C) and the rate of ...
J Feeney, C Pascual
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Pirenzepine affects scleral metabolic changes in myopia through a non-toxic mechanism
, 2002 Whilst the precise mechanism regulating ocular growth is unknown, it has been shown that various pharmacological agents, including the muscarinic receptor antagonists, atropine and pirenzepine, are effective at preventing the development of myopia.
CL Cottriall (14542697) +3 more
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